Doctor insights on:
Hereditary Ovarian Cancer In Children
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
More than one member: Hereditary Ovarian cancer (often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives (parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test which can be don ...Read more
BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research. ...Read more
Prevention.: Most hereditary ovarian cancer is caused by BRCA genes. The key is prevention. US, blood work and a physical exam every six moths. Oral contraceptives can decrease risk of ovarian cancer. If BRCA positive then removal of tubes and ovaries at about 35 or after childbearing. Need to make a cancer prevention plan with doctor. Also need close relatives to be aware of risk. Hope this helps. ...Read more
Genetic Syndrome: Basically this is a familial cancer syndrome. This is due to a genetic defect which is passed down from paretn to child. (can actually come from a man). In the case of ovarian cancer it is usually associated with the brca gene when someone speaks of hereditary ovarain cancer. ...Read more
Be honest.: It's important to be honest with them. Cancer is understandably a shocking and emotionally taxing thing for everyone involved, so keeping everyone on the same page will allow you and your loved ones to support each other through difficult times. Keep them, as well as yourself, informed of all the amazing resources out there to help patients and their families cope with their situation. ...Read more
That's a lot: Six is a lot of abortions, but sometimes we have to abort and destroy a baby fetus in order to prevent giving birth to a baby with genetic mutations. One's body does not get a higher chance of ovarian or breast cancer from abortions. A woman has a lower chance of these cancers if she spends more of her life being pregnant and breastfeeding afterwards... so having six kids can be a good thing. ...Read more
My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?
About 8.5%: Less then 10% of ovarian cancers are currently known to arise from inherited mutations. ...Read more
Often it is not gene: Only 10-20% cases are genetic or hereditary in origin, rest are sporadic or not related to previous family history...Just come out of the blue in more than 80% of cases. ...Read more
Should I screen my children for ovarian cancer genes since it seems to be so deadly? There is no history in my family.
I had testicular cancer and his sister died of ovarian cancer. Is this just a terrible coincidence or could it be hereditary?
My aunt (dad's sis) and grt-grandma (pat grandma's mom) both died of ovarian cancer. How likely is it hereditary? Would genetic testing be good idea?
Possibly: Two family members with ovarian cancer is not that common. There are a few inherited conditions that increase ovarian cancer risk. I would suggest that you gather all family info you can get hold of (all family with or without cancer) and visit with your gyn or family doc. They will decide of you need to be seen by a specialist in hereditary cancer. ...Read more
There is a gene you can have that makes you more likely to get breast and ovarian cancer that is hereditary. What gene is that?
Am 32 - no children yet. Best way to determine 1.Ovarian cancer-pap smear or ca 125 & 2.Breast cancer-mammography or ca 15-3 granny died of ovarian ca?
Pelvis & abomen: Commonly when advaced spreads in the abdomen affecting the peritoneum producing increased intra pelvic and abdominal fluid. As most cancers may spread to liver, lung, brain, bone. Most ovarian cancer produce symptoms only in advanced stages with nonspecific sensations of increased belly or intraabdominally discomfort. Ca 125 is not a screening test because of so many false positives and negatives. ...Read more
In some cases: In some cases of ovarian cancer, a mass (or masses) can be felt in the pelvis with a manual vaginal examination. In advanced cases, a swollen abdomen from ascites can be seen on exam (but this is not specific for ovarian cancer). In most cases of ovarian cancer, the findings on exam are quite nonspecific. ...Read more
Depends.: It is notoriously hard to detect early. Pelvic ultrasound and family history along with serum ca-125 are some approaches to early detection that have not been particularly effective. Current research is aiming at identifying a serum proteomic signature of early ovarian cancer that can be clinically useful. ...Read more
Non specific: Symptoms of ovarian cancer are not specific. They often mimic other common conditions. These may include: abdominal pressure, fullness, swelling or bloating, pelvic discomfort or pain, persistent indigestion, gas or nausea, changes in bowel habits, such as constipation, changes in bladder habits, including a frequent need to urinate, loss of appetite or quickly feeling full, and low back pain. ...Read more
Not very likely: The actual answer to this depends on whether there is a family history of ovarian cancer. If a close family member of the 25 year old has had ovarian cancer then the family could carry the brca gene which would increase the possibility of ovarian cancer. Symptoms of ovarian cancer are generally bloating and possibly abdominal pain. An ultrasound of the ovaries will find cancer. ...Read more
Hereditary Ovarian cancer (often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives (parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test ...Read more
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