Top
30
Doctor insights on: Hereditary Ovarian Cancer

Share
Dr. John Geisler
17 doctors shared insights

Hereditary Ovarian Cancer (Overview)

Hereditary Ovarian cancer(often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives(parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test which can be don


1

1
What are the symptoms of hereditary ovarian cancer?

What are the symptoms of hereditary ovarian cancer?

Same as regular: Ovarian cancer. Unfortunately, there are no specific symptoms in early ovarian cancer. Most women have vague abdominal symptoms and at later stages, abdominal swelling, mass, symptoms from mets, weakness etc. ...Read more

Dr. John Geisler
17 doctors shared insights

Hereditary Ovarian Cancer (Overview)

Hereditary Ovarian cancer(often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives(parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test which can be don


2

2
What are the tests for hereditary ovarian cancer?

What are the tests for hereditary ovarian cancer?

Ultrasound: Pelvic/transvaginal ultrasound is the best test after a good physical exam for a suspected ovarian cancer of any kind. ...Read more

3

3
Living with Polycystic Ovarian Syndrome (Checklist)

Eliminate low-fat, high-carb foods from your diet
once
Monitor your weight and review your diet daily
daily
Blend exercises that make sense into your daily routine
daily
4

4
What genes cause hereditary ovarian cancer?

BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research. ...Read more

5

5
What is the treatment for hereditary ovarian cancer?

What is the treatment for hereditary ovarian cancer?

Prevention.: Most hereditary ovarian cancer is caused by BRCA genes. The key is prevention. US, blood work and a physical exam every six moths. Oral contraceptives can decrease risk of ovarian cancer. If BRCA positive then removal of tubes and ovaries at about 35 or after childbearing. Need to make a cancer prevention plan with doctor. Also need close relatives to be aware of risk. Hope this helps. ...Read more

6

6
Living with Skin Cancer (Checklist)

Avoid sun exposure between 10 am and 2 pm
daily
Apply sunscreen
2x day
Wear a hat outdoors on sunny days
daily
See a dermatologist for checkups
2x year
7

7
What are the tests for hereditary ovarian cancer?

Ultrasound: Pelvic/transvaginal ultrasound is the best test after a good physical exam for a suspected ovarian cancer of any kind. ...Read more

8

8
What are the symptoms of hereditary ovarian cancer?

Same as regular: Ovarian cancer. Unfortunately, there are no specific symptoms in early ovarian cancer. Most women have vague abdominal symptoms and at later stages, abdominal swelling, mass, symptoms from mets, weakness etc. ...Read more

9

9
Managing Pain from Cancer (Checklist)

Ask an oncologist to refer you to a cancer pain specialist
Once
Ask a pain specialist about both interventional and medication options
Once
If you have pancreatic cancer, ask about a celiac plexus block
Once
If you have neuropathy, request a trial of ketamine-based topical creams
Once
10

10
What is the definition or description of: Hereditary ovarian cancer?

What is the definition or description of: Hereditary ovarian cancer?

More than one member: Hereditary Ovarian cancer(often in combination with Breast Cancer) runs in 10 of Ovarian cancers. It should be considered and confirm by genetic testing if there is high suspicion based on 2 or more first degree relatives(parents, sisters or maternal aunts) suffering from Ovarian or Breast Cancer. The diagnosis is confirmed if you are a carrier for BRCA gene mutation (genetic test which can be don ...Read more

11

11
What genes cause hereditary ovarian cancer?

BRCA 1 and 2: The breast-ovarian cancer (brca 1 and 2) genes are the only ones so far proven to cause susceptibility to ovarian cancer (as high as 50% lifetime risk for ovarian, 85% for breast cancer if you have a mutation. Other ovarian cancer susceptibility genes may be identified by ongoing research. ...Read more

12

12
I need a straight answer. What is hereditary ovarian cancer?

I need a straight answer. What is hereditary ovarian cancer?

Genetic Syndrome: Basically this is a familial cancer syndrome. This is due to a genetic defect which is passed down from paretn to child. (can actually come from a man). In the case of ovarian cancer it is usually associated with the brca gene when someone speaks of hereditary ovarain cancer. ...Read more

13

13
What is the treatment for hereditary ovarian cancer?

Prevention.: Most hereditary ovarian cancer is caused by BRCA genes. The key is prevention. US, blood work and a physical exam every six moths. Oral contraceptives can decrease risk of ovarian cancer. If BRCA positive then removal of tubes and ovaries at about 35 or after childbearing. Need to make a cancer prevention plan with doctor. Also need close relatives to be aware of risk. Hope this helps. ...Read more

14

14
My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?

My grandmother may have very advanced ovarian cancer, tests are coming back today. Is ovarian cancer hereditary?

There incresed risk: There is genetic predisposition but most ovarian cancers are not heriditary.If she has brac1;brac2also hnpcc gene.There is increased risk of ovarian cancer if you a menber of your immediate family has ovarian cancer. ...Read more

15

15
Have been diagnosed with ovarian cancer, what are the chances that this was hereditary?

Have been diagnosed with ovarian cancer, what are the chances that this was hereditary?

About 8.5%: Less then 10% of ovarian cancers are currently known to arise from inherited mutations. ...Read more

16

16
Is ovarian cancer more or less likely to be "genetic/hereditary"?

Is ovarian cancer more or less likely to be "genetic/hereditary"?

Often it is not gene: Only 10-20% cases are genetic or hereditary in origin, rest are sporadic or not related to previous family history...Just come out of the blue in more than 80% of cases. ...Read more

17

17
I had testicular cancer and his sister died of ovarian cancer. Is this just a terrible coincidence or could it be hereditary?

I had testicular cancer and his sister died of ovarian cancer. Is this just a terrible coincidence or could it be hereditary?

While these are both: Can be germ cell tumors, there is neither familial or molecular links to cancers of either kid, or the oddity of siblings of opposite sex acquiring them. Most ovarian tumors are not germ cell, but epithelial, the opposite is true of testicular cancer. ...Read more

18

18
Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes.

Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but
quoting wikipedia:

http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

19

19
My aunt (dad's sis) and grt-grandma (pat grandma's mom) both died of ovarian cancer. How likely is it hereditary? Would genetic testing be good idea?

My aunt (dad's sis) and grt-grandma (pat grandma's mom) both died of ovarian cancer.  How likely is it hereditary? Would genetic testing be good idea?

Possibly: Two family members with ovarian cancer is not that common. There are a few inherited conditions that increase ovarian cancer risk. I would suggest that you gather all family info you can get hold of (all family with or without cancer) and visit with your gyn or family doc. They will decide of you need to be seen by a specialist in hereditary cancer. ...Read more

20

20
There is a gene you can have that makes you more likely to get breast and ovarian cancer that is hereditary. What gene is that?

There is a gene you can have that makes you more likely to get breast and ovarian cancer that is hereditary. What gene is that?

BRCA mutation: The gene is called brca, and mutations in this gene are associated with an increased risk of breast and ovarian cancer. Check out this link for more info:
www.Cancer.Gov/cancertopics/.../brca. ...Read more

21

21
Fluid with ovarian cancer?

Fluid with ovarian cancer?

Depends: If you are asking if there is fluid seen with ovarian cancer, then yes some ovarian cancers can cause excess abdominal fluid called ascites. ...Read more

22

22
How common is ovarian cancer?

How common is ovarian cancer?

About 20K per year: In the United States there are about 20, 000 new cases of ovarian cancer per year. ...Read more

23

23
How can I treat ovarian cancer?

How can I treat ovarian cancer?

Depends: It will depend on the stage. Curative surgery in early stage of disease plus minus chemotherapy. Debulking surgery is needed and is done by a gynecology-oncologist if the tumor burden is high - then followed by chemotherapy. The treatment will depend on the stage. ...Read more

24

24
Can ovarian cancer ever be cured?

Can ovarian cancer ever be cured?

Yes: Ovarian cancer can be cured especially when it is discovered early. One of the challenges with ovarian cancer is that it is often discovered when it is more advanced because there are no effective screening tools and the disease can often be asymptomatic until it is more advanced. ...Read more

25

25
Who is at risk for ovarian cancer?

Who is at risk for ovarian cancer?

Increased risk...: ...is associated with increased age, women with a family history of ovarian or breast cancer, women with the genetic BRCA modifications, and certain ethnicities. These groups have a higher risk than the overall lifetime risk for women in the US of 1.6%. ...Read more

26

26
What age does ovarian cancer strike?

Depend: It really depend on your genes if you have strong family history of ovarian or breast cancer it might strike earlier you doctor can run test on your gene to make sure you do not have the one that can cause cancer ...Read more

27

27
What type of ovarian cancer do I have?

What type of ovarian cancer do I have?

Depends on your path: You should discuss your pathology with your doctor. There are different types of ovarian cancer including: borderline tumors (tumors of low malignany potential) and epithelial tumors (papillary serous, mucinous and endometrioid, clear cell, transitional cell, undifferentiated), for example. ...Read more

28

28
When should ovarian cancer be detected?

As early as possible: Unfortunately, ovarian cancer is often missed during its early stages, as it either causes no symptoms at all, or only very general symptoms, until it becomes quite advanced. Like all cancers, though, ovarian cancer has a much higher cure rate when detected at an early stage, . ...Read more

29

29
How do I know if I have ovarian cancer?

Not easy: There are no specific symptoms of ovarian cancer, especially early ovarian cancer. The symptoms are usually vague fullness, gas, pelvic discomfort or pain, urinary symptoms etc. See this site for more info.
http://www.mayoclinic.com/health/ovarian-cancer/ds00293. ...Read more

30

30
What are some symptoms of ovarian cancer?

Or none: One of the reasons that ovarian cancer has such a poor prognosis overall is that it usually does not cause symptoms and thus is not found until it has become fairly advanced and more difficult to treat. While it can cause vague spyoma as described most cases are asymptomatic until its had a chance to progress. If you have a concern or are at high risk genetically, talk to your md about screening. ...Read more

Dr. Barry Rosen
4,344 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Gurmukh Singh
501 doctors shared insights

Ovarian Cancer (Definition)

A typically silend cancer which ...Read more