Doctor insights on:
Hereditary Nonpolyposis Colon Cancer
Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more
Several.: The types of colorectal cancers you refer to include hnpcc (hereditary nonpolyposis colorectal cancer) and fap (familial adenomatous polyposis). However, each of these can also arise form a new mutation with no family history. Garden variety colorectal cancer also has some heritability, though far less than those noted above. ...Read moreSee 1 more doctor answer
Family risk: You will want to get colonoscopy from time to time starting soon. Your family members may also be checked for genetic problems such as HPNCC and familial polyposis; if they are affected, you may be checked as well. Getting 'scoped frequently greatly diminishes your risk of dying of this illness. ...Read more
If theres hereditary predisposition of colon cancer how often should a person do colonoscopy and wha are the risk factors? And What is polyposis test?
Colon CA/screening: ACS screening for families that have a strong history. There are families that have predisposition to develop color and rectal CA. They say screening should start 10 yrs prior to the family members Dx. Say mom Dx at 40, screening would start at 30 in her family. Once you've had the first scope re can be made on the frequency, every 3 to 5 yrs depending on number of members Dx. ...Read more
Can be: Most colon cancers relate more to lifestyle than inheritance but some patients do have an inherited predisposition, be it in the setting of multiple polyps (like fap or myh) or not (lynch syndrome). Families with this have early onset colon cancer and other cancers as well. Talk to your doc about this to see if you need to visit a specialist in inherited malignancies. Remember to live healthy. ...Read more
Not in 400 character: Many genes are linked with an increased risk of colon cancer (and others), so those with a family history of colon, uterine and other cancers are at increased risk as they may inherit these genes from their parents. Genetic testing can pinpoint some of these genes and thus indicate whether you are at increased risk, thus allowing earlier detection/prevention/treatment so get checked if this appies. ...Read moreSee 1 more doctor answer
If a person in their mid 30's were to get colon cancer would it almost always be due to a hereditary form of cancer compared to sporadic?
Maybe: Some hereditary factors increase colon cancer risks such as some types of colitis (ulcerative colitis, crohn's disease), familial polyposis, hnpcc, lynch syndrome, etc. But younger people can get spontaneous colon cancers too. Get a referral to a gastroenterologist as indicated. Most colon cancer occurs after age 50, and reported 8-10 people per 100, 000 get colon cancer under age 50. ...Read moreSee 1 more doctor answer
Genes: Most colon cancers are not inherited. However, there is a subset which is associated with inherited genetic abnormalities such as hereditary polyposis a this hereditary non polyposis gene (hnpp). There are also syndromes that make you susceptible to a variety of different cancers including colon cancer such as lynch syndrome. ...Read moreSee 2 more doctor answers
Final few yards of your intestine, between the terminal ileum (small bowell) and rectum. It squeezes water and solidifies waste to stool. It is subject to outpouching (divertics) polyps, and these can become cancers. The cells are abnormal, invade into the muscle and travel ...Read more
- Talk to a doctor live online for free
- Nonpolyposis colon cancer
- Familial nonpolyposis colon cancer
- Hereditary colon cancer syndromes
- Ask a doctor a question free online
- Hereditary colon cancer
- Are colon polyps hereditary?
- Is a twisty loopy colon hereditary?
- Prostate cancer hereditary
- Talk to a oncologist online for free