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Doctor insights on: Herceptin And Breast Cancer Progression

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Dr. Barry Rosen
1,337 doctors shared insights

Breast Cancer (Definition)

Breast cancer results when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. The growth occurs initially inside the ducts but eventually breaks outside into the breast tissue and ultimately spreads both to the lymph nodes in the armpit and via the bloodstream to other parts of the body. Because of the promoting affect of estrogen almost all breast cancer occurs in women and is a rarity in men. The unregulated growth is due to both inherited and acquired genetic defects. It is the most common malignancy in women but it often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


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What does herceptin (trastuzumab) do for breast cancer patients?

What does herceptin (trastuzumab) do for breast cancer patients?

Herceptin (trastuzumab) : Herceptin (trastuzumab) is one of targetted therapy that we can use to treat a her2 positive breast cancer. There are other her 2 receptor inhibitors out there- such as lapatinib, Pertuzumab and hopefully tdm1. It is able to stop the cancer from growing and ultimately cause death to cancer cells that have the her2 receptors. ...Read more

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Why is herceptin (trastuzumab) licensed for use of advanced but not early breast cancer?

Why is herceptin (trastuzumab) licensed for use of advanced but not early breast cancer?

Used in both setting: For your information, Herceptin (trastuzumab) is used and indicated for both settings- for early breast cancer- at least is given for 1 year - as well as for advanced metastatic breast cancer. ...Read more

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Is herceptin (trastuzumab) just can heal breast cancer?

Herceptin (trastuzumab): Herceptin (trastuzumab) is approved for the treatment of early-stage breast cancer that is human epidermal growth factor receptor 2-positive (her2+) and has spread into the lymph nodes, or is her2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (er/pr)-negative or have one high risk feature. ...Read more

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What do I need to know about herceptin (trastuzumab) after breast cancer?

What do I need to know about  herceptin (trastuzumab) after breast cancer?

Herceptin (trastuzumab): Herceptin (trastuzumab) is a targetted therapy that inhibits her2-neu receptor . Herceptin (trastuzumab) has been given to patient with her2neu receptor positive breast cancer with improvement of response and survival. Herceptin (trastuzumab) has been also one of treatment options for her2 reeptor positive stomach cancer. Read. Mire about Herceptin (trastuzumab) at www.Cancer.Net, www.Cancer.Org, www.Nccn.Com. ...Read more

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Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Why do they treat some woman with breast cancer with herceptin (trastuzumab)?

Herceptin (trastuzumab) breast ca: About 1/4 cases of breast cancer express a protein on the surface of the cancer cells called her2neu which is a member of the epidermal growth factor family of receptors important for growth signaling into the cell nucleus. Herceptin (trastuzumab) is an antibody developed to target her2neu and antagonize this growth signaling and kill the cancer cell. Chemo is synergistic with Herceptin (trastuzumab) when given together. ...Read more

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Does being on herceptin (trastuzumab) for breast cancer cause you to gain weight?

Does being on herceptin (trastuzumab) for breast cancer cause you to gain weight?

No: Herceptin (trastuzumab) is not associated with weight gain. However sometimes weight gain can happen during or following chemotherapy due to the use of steroids prior to chemotherapy. However not related to Herceptin (trastuzumab) use. ...Read more

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Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read more

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Is there any oral maintenance medicine fot her2 breast cancer after finishing the herceptin (trastuzumab)?

Is there any oral maintenance medicine fot her2  breast cancer after finishing the herceptin (trastuzumab)?

Hormonal treatment: If the cancer is er positive then tamoxifen or an aromatase inhibitor would be beneficial to reduce the risk of recurrence. ...Read more

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Dr. Barry Rosen
4,223 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Mark Hoepfner
1,029 doctors shared insights

Breast Carcinoma (Definition)

Breast carcinoma is a type of cancer where this uncontrolled growth of breast cells. Symptoms can include breast lumps, pain, and weight ...Read more