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Doctor insights on: Herceptin Allergy In Children

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I have a light white spot on my arms and legs and its a little bit itchy. I'm a breast cancer patient and presently taking up herceptin (trastuzumab). Is this an allergy pr fungal?

I have a light white spot on my arms and legs and its a little bit itchy. I'm a breast cancer patient and presently taking up herceptin (trastuzumab). Is this an allergy pr fungal?

Doctor can evaluate: Rashes are hard to describe in words, so a primary care doctor or a dermatologist can look at it and evaluate. A light colored spot that is a bit itchy could be just eczema (a dry spot of sensitive skin that gets a bit itchy, a bit flaky, a bit crackly, etc...). It could be fungal, such as tinea versicolor (but that usually is a bunch of spots). Other rashes are possible, so an exam will help. ...Read more

Dr. John Chiu
2,628 Doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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How does herceptin (trastuzumab) work?

How does herceptin (trastuzumab) work?

Binds to tumor: Herceptin (trastuzumab) is a man-made antibody that binds to cancer cells if they express the her2 receptor. It acts like "seasoning" for the immune system, attracting immune cells which kill the tumor cells. That's a simplistic explanation, because no one really understands what happens when Herceptin (trastuzumab) binds to tumor cells. There are many theories, but we know immune cells are necessary for it to work. ...Read more

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How exactly does herceptin (trastuzumab) work?

How exactly does herceptin (trastuzumab) work?

Blocks cell growth: Herceptin (trastuzumab) is a "monoclonal antibody". It is a protein that binds to receptors on breast cancer cells called her-2. Her-2 causes breast cancer cells to grow uncontrollably. When Herceptin (trastuzumab) binds to these cells, it slows their growth. However, not all breast cancer cells contain the her-2 receptors. Patients must be tested for the presence of her-2 receptors before they are started on herceptin (trastuzumab). ...Read more

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Who should avoid taking herceptin (trastuzumab)?

Who should avoid taking herceptin (trastuzumab)?

History heart failur: There are many considerations, but you should not take Herceptin (trastuzumab) if you have a history of congestive heart failure. Visit with your doctor to see if Herceptin (trastuzumab) is right for you. ...Read more

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Can you tell me what are contraindications of herceptin (trastuzumab)?

None except...: There are no contraindications to this medication but it should not be used in pregnant women because of possible harm to the baby. ...Read more

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Side effects of herceptin (trastuzumab)?

Side effects of herceptin (trastuzumab)?

Heart failure: About 4% of women treated with Herceptin (trastuzumab) develop some weakness in their heart as measured by a muga test. This decrease in heart function is reversible when the drug is stopped. Other side effects of Herceptin (trastuzumab) can include allergic reaction, fatigue, headache and diarrhea. Most of my patients have no side effects! ...Read more

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Unpleasant side effects of herceptin (trastuzumab)?

Unpleasant side effects of herceptin (trastuzumab)?

Heart failure: About 4% of women treated with Herceptin (trastuzumab) develop some weakness in their heart. This decrease in heart function is almost always reversible when the drug is stopped. Other side effects of Herceptin (trastuzumab) can include allergic reaction, fatigue, headache and diarrhea. Most of my patients have no side effects! ...Read more

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What is the effect of herceptin (trastuzumab) on tumor?

What is the effect of herceptin (trastuzumab) on tumor?

To kill cancer cells: Herceptin (trastuzumab)-or traztuzumab is an humanized antibody againsts her2neu receptor. This biological therapy is given to treat certain cancers that are positive for her2neu receptors on their cancer cells. Once the Herceptin (trastuzumab) binds the her2neu receptors on the cancer cells, it will supress cancer cells proliferation/growth that lead to cancer cells stasis and eventually will apoptosis/die. ...Read more

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How can herceptin (trastuzumab) affect the heart?

How can herceptin (trastuzumab) affect the heart?

Herceptin (trastuzumab): It can cause weakening of the heart muscle and heart failure.
Read this for details about herceptin.

http://en. Wikipedia. Org/wiki/trastuzumab. ...Read more

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What are the risks with herceptin (trastuzumab) therapy?

What are the risks with herceptin (trastuzumab) therapy?

Heart failure: About 4% of women treated with Herceptin (trastuzumab) develop some weakness in their heart as measured by a muga test. This decrease in heart function is reversible when the drug is stopped. Other side effects of Herceptin (trastuzumab) can include allergic reaction, fatigue, headache and diarrhea. Most of my patients have no side effects! ...Read more

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What are common adverse reactions of herceptin (trastuzumab)?

What are common adverse reactions of herceptin (trastuzumab)?

Various: There are many common adverse reactions to herceptin (trastuzumab). These include pain fevers, chills, nausea, vomiting, diarrhea, headache, fatigue, cough, trouble breathing, rash, infections, lack of appetite, swelling, and changes in your blood counts. Additionally, Herceptin (trastuzumab) is sometimes combined with other medications which can cause a different set of adverse reactions. ...Read more

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Can you tell me how herceptin (trastuzumab) affect the heart?

Can you tell me how herceptin (trastuzumab) affect the heart?

Heart failure: Most commonly (though still very uncommon) it can cause heart failure - most often reversible upon holding the drug. It has been demonstrated to be safely readministered in many patients. ...Read more

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How is herceptin (trastuzumab) therapy administered to a patient?

Intravenously.: Herceptin (trastuzumab) is given through an iv, typically in your cancer doctor's office. ...Read more

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How long must I wait before I can get pregnant after using herceptin (trastuzumab)?

How long must I wait before I can get pregnant after using herceptin (trastuzumab)?

See: It seems that getting pregnant more than 6 months after last Herceptin (trastuzumab) exposure is safe. I suggest contacting:

http://herceptinpregnancyregistry. Com/contact. Htm

for more information. ...Read more

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Want to stay on herceptin (trastuzumab) and switch from Taxol to gemzar. What is the difference?

Want to stay on herceptin (trastuzumab) and switch from Taxol to gemzar. What is the difference?

Less neuropathy: Unlike taxol, (paclitaxel) gemcitabine does not cause neuropathy. It can cause low platelets. It can also cause fluid retention. Also it is usually given 2 weeks on and 1 week off. Unlike Taxol (paclitaxel) which typically is given weekly. That is about it in regards to the difference. Hope this helps. ...Read more

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Where can I buy herceptin (trastuzumab)?

Where can I buy herceptin (trastuzumab)?

Herceptin (trastuzumab) is: A medication that is typically given by an oncologist. Consult your doctor. ...Read more

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Where can you get herceptin (trastuzumab)?

Herceptin (trastuzumab): Herceptin (trastuzumab) is a prescription medication that prescribed by a medical oncologist for breast cancers that are HER2/neu positive or HER2/neu amplified. It is administered intravenously and is not available over the counter. ...Read more

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What is the cost of herceptin (trastuzumab)?

What is the cost of herceptin (trastuzumab)?

Thousands!: In the us, the cost of Herceptin (trastuzumab) depends on who gives it to you and what kind of insurance you have. Patient's bills are in the range of $2000 to over &7000 per treatment. Why the difference? Medicare limits how much the cost can be "marked up" from the purchase price, but other insurance companies aren't as strict. So... The cost is what the market will bear, sadly. ...Read more

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How long could herceptin (trastuzumab) stay in the body?

About a week: Half life of 2 days. That means that half the blood level is gone in two days. Then, another 50% is gone in another two days, etc. ...Read more

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Which company offers the best quality of herceptin (trastuzumab)?

Genentech: The US patent on trastuzumab ("Herceptin") expires in June of 2019, so only Genentech is allowed to produce it. In Europe, the patent expired in June of 2014, but I don't know if the European Medicines Agency has yet approved any biosimilars ("generics"). ...Read more

Dr. Jan Lei Iwata
60 Doctors shared insights

Trastuzumab (Definition)

Trastuzumab is an antibody based agent which is a kind of ...Read more


Dr. Cornelius O'leary jr
66 Doctors shared insights

Herceptin (Definition)

Herceptin ...Read more