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Doctor insights on: Her2 Neu Breast Cancer

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Dr. Barry Rosen
4,357 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
4 doctors agreed:
Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Treatment for her2 breast cancer?

Treatment for her2 breast cancer?

Herceptin (trastuzumab): The local treatment option (breast conservation versus mastectomy) are the same. The diff comes with systemic therapy. Her2+ cancers are more aggressive but this is counteracted by the biological (antibody) herceptin (trastuzumab). This is generally given with chemo. Since this is the case, it may often given before surgery (neoadj) to gain additional prognostic info and shrink the primary. ...Read more

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What is inflammatory breast cancer?

What is inflammatory breast cancer?

Type of cancer: Inflammatory breast cancer is a rare and very aggressive disease in which cancer cells block lymph vessels in the skin of the breast. This type of breast cancer is called “inflammatory” because the breast often looks swollen and red, or “inflamed.” inflammatory breast cancer accounts for 1 to 5 percent of all breast cancers diagnosed in the United States. ...Read more

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Anyone have stage 1 breast cancer with her2/neu positive er/pr negative?

Anyone have stage 1 breast cancer with her2/neu positive er/pr negative?

Yes: Breast cancers can be highly variable from one person to the next. Cell types and dna evaluations can be performed now that can help direct the best treatments for each person. Her-2 breast cancers may be best treated with specialized chemotherapy agent heceptin. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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Dr. Liawaty Ho Dr. Ho
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My mom has metastatic breast cancer ?

Dr. Liawaty Ho Dr. Ho
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My mom has metastatic breast cancer ?

Stage IV: I hope your mom is okay. Metastatic breast cancer is condition when the cancer has spread beyond the breast. It commonly spreads to the liver, lung, bones, brain. It is unfortunately an incurable disease-although it is treatable. Therapy will depend on the biology of the cancer and your mother's overall health condition and her preference. We do have chemo, targetted therapy, hormonal therapy ...Read more

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Could breast cancer usually metastasize?

Could breast cancer usually metastasize?

Possible: Breast cancer can metastasize. The risk is really dependent on the stage. For a stage i, the risk is. ...Read more

Dr. Liawaty Ho Dr. Ho
6 doctors agreed:
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Does breast pain signal breast cancer?

Dr. Liawaty Ho Dr. Ho
6 doctors agreed:
Does breast pain signal breast cancer?

Not common: Breast pain although can be part of presentation of breast cancer- however, it is not a common sign of breast cancer. Many things can give breast pain including- cyclical changes ( hormonal changes related to period), hormonal imbalance, fibrocystic disease of the breast, inflammation, infection/abscess, caffeine, trauma, large breast size with a poor bra support etc, all can give you breast pain. ...Read more

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What is estrogen receptor positive breast cancer?

What is estrogen receptor positive breast cancer?

One with receptors.: These are tumors with estrogen receptors on them. This makes them susceptable to some chemotherapeutic agents, like tamoxifen. ...Read more

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Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Stage 3 breast cancer her2 positive how many herceptin (trastuzumab) cycle she must undergo?

Up to 1 year's worth: Herceptin (trastuzumab) can be given together with initial chemotherapy for the first 4-6 months then subsequently by itself for a total of 1 year. If chemotherapy was given first without Herceptin (trastuzumab) then Herceptin (trastuzumab) can be given for a full year by itself. The usual cycle runs every 3 weeks (17-18 cycles in one full year). ...Read more

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Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Is chemotherapy required for stage 1A IDC breast cancer, tumor size 1.1 cm, ER & PR positive, HER2 negative, nuclear grade 1. Patient is 42 years old.

Borderline call!: Your breast tumor is quite small, so it has >90% odds that it can be safely treated with surgery, without any chemotherapy required. You may ask your doctor for treating you with tamoxifen which is a antihormone type of medication, commonly used as the treatment for tumors that are ER positive. Good luck ...Read more

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Breast cancer symptoms?

Breast cancer symptoms?

Many or none: Proper screening with self breast exams looking for new lumps, breast exams by your physician looking for skin or nipple chanes as well as masses or lymph nodes, and mammogram and ultrasound if needed are the best ways to pick up early stage breast cancer before it causes any symptoms. Once advanced it can cause many different symptoms throughout the body. ...Read more

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What is breast cancer sentinel node micro metastases?

What is breast cancer sentinel node micro metastases?

Spread of cells: Micrometastasis means that a few tumor cells have left the breast tumor and traveled to the lymph nodes under the arm. In most cases, this is treated as a negative lymph node. I encourage you to review your pathology report with your surgeon and oncologists (ideally they are communicating with each other through a meeting called a tumor board). ...Read more

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O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.

O had surgery for positive breast cancer. Is sentinel lymph node biopsy accurate for breast cancer surgery. Node was negative.

Yes they are: by now sentinel lymph node are the standard of care for breast cancer surgery and staging, and yes they are very accurate. node is negative is a very good news that will make the cancer early stage and hopefully cureable ...Read more

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What is ductal incarcinoma (breast cancer )?

What is ductal incarcinoma (breast cancer )?

Breast Cancer: Learn more about intraductal carcinoma of the breast at: http://www.Intraductalcarcinoma.Net/. ...Read more

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32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy. What is survival rate?

32 YO, triple positive, grade 3, stage 1B breast cancer. TCH chemotherphy, had dbl mastectomy.  What is survival rate?

Need Clarification!: Are you sure your breast cancer was triple positive(or was it triple Negative)??? TCH is commonly used chemotherapy for triple negative, so please double check and let us know. Then we can give you survival figures. In general, small tumors(Stage 1 and stage 2) have very good survival rate and high cure rates. ...Read more

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What is metastatic breast cancer?

What is metastatic breast cancer?

Spread : This means that the cancer has spread to other areas outside of the breast. This is known as stage 4. With the use of modern chemotherapy, this disease can be controlled. I recommend you meet with your medical oncologist to determine options available for treatment. ...Read more

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Dr. Mark Hoepfner
1,063 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more


Dr. Barry Rosen
1,381 doctors shared insights

Breast Cancer (Definition)

A condition in which cells lining the inside of the breast grow ...Read more