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Doctor insights on: Her2 Mutation Breast Cancer

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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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Dr. Barry Rosen
4,404 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is breast cancer inherited?

Is breast cancer inherited?

Sometimes.: It is estimated that approximately 10-15% of all breast cancers in the US are of the hereditary type. These genes can be inherited from either your father or your mother. If a woman inherits this gene, they have a 50-75% chance of developing breast cancer in their lifetime. These cancers tend to occur at any earlier age and may occur in both breasts. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Is breast cancer hereditary?

Is breast cancer hereditary?

Sometimes.: It is estimated that 10-15% of all breast cancer cases in the us occur due to hereditary factors. This risk may be identified by doing a simple blood test to check for brca mutations. We generally advise testing family members with known breast cancers first before checking unaffected family. ...Read more

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Abdominal carcinamatosis from breast cancer metastasis?

Abdominal carcinamatosis from breast cancer metastasis?

Could Be: You have a known breast ca? Any other mets? Typically, one would expect mets to bone before abdomen. If pathology on both sites is the same then probably mets. If not, possible second primary (like ovary). Good luck. ...Read more

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Dr. Liawaty Ho Dr. Ho
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My mom has metastatic breast cancer ?

Dr. Liawaty Ho Dr. Ho
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My mom has metastatic breast cancer ?

Stage IV: I hope your mom is okay. Metastatic breast cancer is condition when the cancer has spread beyond the breast. It commonly spreads to the liver, lung, bones, brain. It is unfortunately an incurable disease-although it is treatable. Therapy will depend on the biology of the cancer and your mother's overall health condition and her preference. We do have chemo, targetted therapy, hormonal therapy ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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Could breast cancer usually metastasize?

Could breast cancer usually metastasize?

Possible: Breast cancer can metastasize. The risk is really dependent on the stage. For a stage i, the risk is. ...Read more

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Can ovarian cancer and breast cancer be hereditary?

Can ovarian cancer and breast cancer be hereditary?

Yes, of course: This is one of the classic hereditary cancer syndromes. Sorry, i don't have enough characters to be allowed to give you a full asnwer here, but quoting wikipedia: http://en.Wikipedia.Org/wiki/hereditary_breast%e2%80%93ovarian_cancer_syndrome. ...Read more

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What is ductal incarcinoma (breast cancer )?

What is ductal incarcinoma (breast cancer )?

Breast Cancer: Learn more about intraductal carcinoma of the breast at: http://www.Intraductalcarcinoma.Net/. ...Read more

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Is breast cancer autosomal dominant?

Is breast cancer autosomal dominant?

Well...: ...most breast cancers (80-90%) are not related to inherited traits so in those cases your question does not apply. However, the majority of high risk genes that cause breast and other cancers (like BRCA) are indeed transmitted as autosomal dominant traits. ...Read more

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What distinguishes inflammatory breast cancer from invasive breast cancer?

What distinguishes inflammatory breast cancer from invasive breast cancer?

Inflammatory breast: Cancer is a subtype of invasive breast cancer that involves the skin. It causes the skin to appear inflamed. ...Read more

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Is ovarian cancer genetic?

Is ovarian cancer genetic?

Sometimes: Certain genotypes such as the brca mutations have a higher incidence of ovarian cancer. ...Read more

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Can I inherit breast cancer?

Can I inherit breast cancer?

Not directly: Breast cancer is not directly passed from parent to child. However, an increased risk of developing breast cancer can be inherited. Mutations in the genes brca1 and brca2 increase your chance of developing breast cancer. You are not 100% guaranteed to get breast cancer if you inherit these genes, but the risk can be as high as 85%. ...Read more

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Does male breast cancer have different symptoms from female breast cancer?

Does male breast cancer have different symptoms from female breast cancer?

Not really: Most breast cancers are without symptoms. That is why many are missed. Males having such little breast tissue may notice a lump earlier but not always so many go undetected because few realize that men are also susceptible to breast cancer. ...Read more

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Anyone have stage 1 breast cancer with her2/neu positive er/pr negative?

Yes: Breast cancers can be highly variable from one person to the next. Cell types and dna evaluations can be performed now that can help direct the best treatments for each person. Her-2 breast cancers may be best treated with specialized chemotherapy agent heceptin. ...Read more

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Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

Dr. Liawaty Ho Dr. Ho
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Chemotherapy hormone receptor positive node breast cancer?

D/W oncologist: Treatment will depend not only the stage but also the biology of the cancer- whether it is estrogen positive, her2neu positive, whether it is lymph node positive or not. Also depends on your preference and overall health condition. Different test like oncotype dx, mammaprint can give you more info-re- recurrence risk of cancer and will be helpful in choosing the right therapy for you.D/w your md. ...Read more

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Does breast cancer increase colon cancer risk?

Does breast cancer increase colon cancer risk?

Rarely.: Some hereditary mutations may increase the risk of both breast and colon cancer. Nevertheless, the majority of all breast and colon cancers are not hereditary. ...Read more

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Breast cancer symptoms?

Breast cancer symptoms?

Many or none: Proper screening with self breast exams looking for new lumps, breast exams by your physician looking for skin or nipple chanes as well as masses or lymph nodes, and mammogram and ultrasound if needed are the best ways to pick up early stage breast cancer before it causes any symptoms. Once advanced it can cause many different symptoms throughout the body. ...Read more

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Could breast cancer be inherited?

Could breast cancer be inherited?

Yes/no: Cancer is not inherited but you can inherit certain genetic changes that make it more likely to get breast cancer (and others as well). About 1 in 10 breast cancers have an inherited component, most due to brca 1 or 2. Other genes can also be at play, like p53, pten, stk11, atm and others. Discuss this with your doc and see if you would benefit of a visit with a cancer geneticist. ...Read more

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Mutation (Definition)

In genetics, a mutation is a change in the nucleotide sequence of the genome of an organism, virus, or extrachromosomal genetic element. Mutations result from unrepaired damage to dna or to RNA genomes (typically caused by radiation or chemical mutagens), from errors in the process of replication, or from the insertion or deletion of segments of dna ...Read more


Dr. Mark Hoepfner
1,068 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more