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Doctor insights on: Her2 Breast Cancer

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Treatment for her2 breast cancer?

Treatment for her2 breast cancer?

Herceptin (trastuzumab): The local treatment option (breast conservation versus mastectomy) are the same. The diff comes with systemic therapy. Her2+ cancers are more aggressive but this is counteracted by the biological (antibody) herceptin (trastuzumab). This is generally given with chemo. Since this is the case, it may often given before surgery (neoadj) to gain additional prognostic info and shrink the primary. ...Read more

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Dr. Barry Rosen
4,342 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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Is dcis breast cancer genetic?

Is dcis breast cancer genetic?

It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info: http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full. ...Read more

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What is inflammatory breast cancer?

What is inflammatory breast cancer?

Type of cancer: Inflammatory breast cancer is a rare and very aggressive disease in which cancer cells block lymph vessels in the skin of the breast. This type of breast cancer is called “inflammatory” because the breast often looks swollen and red, or “inflamed.” inflammatory breast cancer accounts for 1 to 5 percent of all breast cancers diagnosed in the United States. ...Read more

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Breast cancer symptoms?

Breast cancer symptoms?

Many or none: Proper screening with self breast exams looking for new lumps, breast exams by your physician looking for skin or nipple chanes as well as masses or lymph nodes, and mammogram and ultrasound if needed are the best ways to pick up early stage breast cancer before it causes any symptoms. Once advanced it can cause many different symptoms throughout the body. ...Read more

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Could breast cancer usually metastasize?

Could breast cancer usually metastasize?

Possible: Breast cancer can metastasize. The risk is really dependent on the stage. For a stage i, the risk is. ...Read more

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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

My mom had lobular breast cancer at 52. Brca negative. Is lobular breast cancer more genetic based than ductal?

No its medullary: a quote from Lancethttp://www.ncbi.nlm.nih.gov/pubmed/9167459: "The occurrence of invasive lobular carcinoma and invasive ductal carcinoma was not significantly different between carriers of BRCA1 or BRCA2 mutations and controls. Medullary or atypical medullary carcinoma was, however, found more often in BRCA1 (13%, p ...Read more

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Abdominal carcinamatosis from breast cancer metastasis?

Abdominal carcinamatosis from breast cancer metastasis?

Could Be: You have a known breast ca? Any other mets? Typically, one would expect mets to bone before abdomen. If pathology on both sites is the same then probably mets. If not, possible second primary (like ovary). Good luck. ...Read more

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My mom has metastatic breast cancer ?

My mom has metastatic breast cancer ?

Stage IV: I hope your mom is okay. Metastatic breast cancer is condition when the cancer has spread beyond the breast. It commonly spreads to the liver, lung, bones, brain. It is unfortunately an incurable disease-although it is treatable. Therapy will depend on the biology of the cancer and your mother's overall health condition and her preference. We do have chemo, targetted therapy, hormonal therapy ...Read more

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Does breast pain signal breast cancer?

Does breast pain signal breast cancer?

Not common: Breast pain although can be part of presentation of breast cancer- however, it is not a common sign of breast cancer. Many things can give breast pain including- cyclical changes ( hormonal changes related to period), hormonal imbalance, fibrocystic disease of the breast, inflammation, infection/abscess, caffeine, trauma, large breast size with a poor bra support etc, all can give you breast pain. ...Read more

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What distinguishes inflammatory breast cancer from invasive breast cancer?

What distinguishes inflammatory breast cancer from invasive breast cancer?

Inflammatory breast: Cancer is a subtype of invasive breast cancer that involves the skin. It causes the skin to appear inflamed. ...Read more

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Do breast cancer tumor hurts?

Do breast cancer tumor hurts?

Not usually...: But there are always exceptions to any rule. Breast cancers can present as a mass, or with nipple discharge, or skin dimpling etc. The only way to know for sure and get some peace of mind is to see your doctor for an evaluation. May need mammogram, ultrasound, MRI and/or a biopsy for a definite determination. Unless you have a strong family history, odds are low you're dealing with a cancer. ...Read more

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Does breast cancer increase colon cancer risk?

Does breast cancer increase colon cancer risk?

Rarely.: Some hereditary mutations may increase the risk of both breast and colon cancer. Nevertheless, the majority of all breast and colon cancers are not hereditary. ...Read more

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Does male breast cancer have different symptoms from female breast cancer?

Does male breast cancer have different symptoms from female breast cancer?

Not really: Most breast cancers are without symptoms. That is why many are missed. Males having such little breast tissue may notice a lump earlier but not always so many go undetected because few realize that men are also susceptible to breast cancer. ...Read more

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What is ductal incarcinoma (breast cancer )?

What is ductal incarcinoma (breast cancer )?

Breast Cancer: Learn more about intraductal carcinoma of the breast at: http://www.Intraductalcarcinoma.Net/. ...Read more

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Silicone breast implants can couse breast cancer?

Silicone breast implants can couse breast cancer?

No but.....: There is no direct link but there are concerns with the potential for implants to interfere with the detection of cancer. Particularly using mammograms. Special views (eklund) must be obtained. Alhtough there may be a delay in diagnosis, there has not been shown to be any effect on survival. With mri, surveillance is improved and may supplant mammography. As stated, alcl may be increased but rare. ...Read more

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Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Do the breast enhancement pills "breast actives" cause breast cancer or uterus cancer?

Unknown: Breast enhancement pills are not regulated and therefore may have various unknown substances in them. Some of those substances, especially if they include estrogen, may increase risk of cancers. ...Read more

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Does fibrocystic breast diesease increase cancer risk?

Does fibrocystic breast diesease increase cancer risk?

No.: Fibrocystic changes, in the truest sense, can only be diagnosed under the microscope after breast biopsy; the only changes associated with increased cancer risk are those with atypia. "fibrocystic disease" has become a catch-all term to describe "lumpy-bumpy" breast tissue, and is an almost-universal phenomenon in any woman who has been seen by a doctor for breast evaluation. ...Read more

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Correlation between breast cancer and ovarian cancer?

Correlation between breast cancer and ovarian cancer?

SMALL: In 90% of cases there is no correlation. In 10% of cases it may be associated with the hereditary breast ovarian syndrome in which brca 1 & brca 2 mutations are responsable for the increase risk and development of these cancers. ...Read more

Dr. Barry Rosen
1,378 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Dr. Mark Hoepfner
1,061 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more