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Doctor insights on: Her 2

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Her 2 (Overview)

Her 2 is an acronym for human epidermal growth factor receptor. This protein may be present on the surface of about 1 out of 5 breast cancer cells as a result of a unique gene mutation. When present, we call this her2-positive breast ca & indicates that it may be more aggressive and less responsive to hormone therapy. However there are special chemotherapy agents that may be more effective & used.


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What is her 2?

What is her 2?

Gene, marker : Her2 refers to a gene present in many normal cells that codes for a cell surface protein. In 10-15% of breast cancers it is amplified (multiple copies producing a lot of the protein) which is associated with a more aggressive tumor. Herceptin (trastuzumab) (an antibody to the protein) reduces this aggressive nature. It's usually given with chemo for synergy. ...Read more

Her 2 (Overview)

Her 2 is an acronym for human epidermal growth factor receptor. This protein may be present on the surface of about 1 out of 5 breast cancer cells as a result of a unique gene mutation. When present, we call this her2-positive breast ca & indicates that it may be more aggressive and less responsive to hormone therapy. However there are special chemotherapy agents that may be more effective & used.


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What does "her 2 neu" mean?

Breast cancer gene: Her2 (human epidermal growth factor receptor 2) also known as neu, erbb-2, cd340 (cluster of differentiation 340) or p185 is a protein that in humans is encoded by the erbb2 gene. Her2 is a member of the epidermal growth factor receptor (egfr/erbb) family. Amplification or over-expression of this gene has been shown to play an important role in the pathogenesis and progression of certain aggressiv. ...Read more

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What is the definition or description of: her 2?

What is the definition or description of: her 2?

Breast CA Receptor: Her 2 is an acronym for human epidermal growth factor receptor. This protein may be present on the surface of about 1 out of 5 breast cancer cells as a result of a unique gene mutation. When present, we call this her2-positive breast ca & indicates that it may be more aggressive and less responsive to hormone therapy. However there are special chemotherapy agents that may be more effective & used. ...Read more

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Is it better to be her 2 positive or her2 negative?

Is it better to be her 2 positive or her2 negative?

Her2 positive: Breast cancer is broken into 4 types - each involves the presence or absence of estrogen, progesterone, and her 2 receptors: luminal a (er/pr positive, her 2 negative), luminal b (er/pr positive, her 2 positive), her 2 (er/pr negative, her 2 positive), triple-negative (er/pr negative, her 2 negative). Patients who are her 2 positive herceptin, (trastuzumab) a powerful drug that greatly improves survival. ...Read more

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Is it possible for a women to start menopause as early as 26? My friend said that's when her grandma started it after she had her 2 kids.. Possible?

Is it possible for a women to start menopause as early as 26? My friend said that's when her grandma started it after she had her 2 kids.. Possible?

Yes: It's possible to start menopause at age 26. However, this is not normal and it's called premature ovarian insufficiency (failure) ie the cessation of ovarian function prior to age 40. Tests should be done to search for a reason and to evaluate for autoimmune adrenal insufficiency which can be fatal. ...Read more

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If a 38 yr old female take ibuprufen everyday 4 over 6 months could they get addicte 2 it n will it cause her 2 go into withdraws after she stoped taking it

If a 38 yr old female take ibuprufen everyday 4 over 6 months could they get addicte 2 it n will it cause her 2 go into withdraws after she stoped taking it

No: Ibuprofen is not an addicting drug. There is no physical dependence so you can just stop taking it. However, there is concern with why she was taking so much for so long, the cause of the pain. And it can cause stomach bleeding, liver and/or kidney problems when taken for long periods of time. ...Read more

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What's the normal amount of feeding of formula for a 2week 4day old newborn? I feed her 2.5 of formula. Am I feeding her too much?

What's the normal amount of feeding of formula for a 2week 4day old newborn? I feed her 2.5 of formula. Am I feeding her too much?

Feeding Amounts: Feeding amounts will vary some based on the weight of your baby. Generally feeding amounts range from 3-4 oz every 3-4 hours. Visit the site healthychildren.org to help with guidelines. Frequent check ups with growth measurements help to determine good nutrition and growth at this age. Assessing wet diapers also helps. All the best. ...Read more

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Gave 4yo Benedryl 6hrs ago now just gave her 2.5 delsum for cough. This ok?

Gave 4yo Benedryl 6hrs ago now just gave her 2.5 delsum for cough. This ok?

Fine: Most of the effects of the Benadryl (diphenhydramine) are worn off by now. What dose was it?We generally do not give cough or cold preparations until age 6. I assume you mean 1/2 tsp del sum? This would be unlikely to harm her but just not usually given. All the best ...Read more

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Gave 4yo Benedryl 5ml 6hrs ago now just gave her 2.5ml delsum for cough. This ok? Weight 38lbs

Gave 4yo Benedryl 5ml 6hrs ago now just gave her 2.5ml delsum for cough. This ok? Weight 38lbs

Yes: This is ok. You could use warm apple juice with honey for cough. Just let her sip it. She is also old enough to let her suck on pieces of cough drops. ...Read more

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My baby just turned 1. Which is better 4 her, stick to baby formula or switch her 2 cow's milk? Which one is healthier? Thank you ☺

My baby just turned 1. Which is better 4 her, stick to baby formula or switch her 2 cow's milk? Which one is healthier? Thank you ☺

Depends: By the time a kid turns one, most have incorporated a variety of semisolid foods. These can easily make up for some of the special features of breast milk or formula. Regular milk, rather than low fat/skim is needed because baby uses the added fat to support brain growth which slows after 2. The extra in formula if not used end up in her pee. ...Read more

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My 17 mth old keeps getting out of her "big girl" bed is it 2 soon 4 her? If not how do I get her 2 stay n bed? Shld i put her bk in2 a crib?

My 17 mth old keeps getting out of her "big girl" bed is it 2 soon 4 her? If not how do I get her 2 stay n bed? Shld i put her bk in2 a crib?

Big Girl Bed: Many toddlers get out of their bed for numerous reasons but continued redirection back to her bed will decrease these night time escapes. Letting her sleep with a favorite blanket or doll may help with the nighttime awakenings. Putting her back in the crib at this time may be more dangerous. But you may want to look into bed rails for toddler beds. ...Read more

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Newborn is 1mth old and weighs 9lb 12oz. I'm feeding her 2.5oz of formula. Is this enough for her current weight? Or shud she be drinking more?

Newborn is 1mth old and weighs 9lb 12oz.  I'm feeding her 2.5oz of formula. Is this enough for her current weight? Or shud she be drinking more?

Volume counts: Babies have a stomach capacity of about half their pound weight in ounces.A 10 lb baby should be able to accommodate 5 oz and pushing the volume up gradually can help increase the time between feedings. As long as baby empties every bottle they can probably handle a little more. ...Read more

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My 23 year old sister has social problems, we cant stay with her 2 min without having a fight. She hates everyone and she enjoy staying alone all time?

My 23 year old sister has social problems, we cant stay with her 2 min without having a fight. She hates everyone and she enjoy staying alone all time?

Needs to seek help: It sounds like she is affected by a condition that is very damaging to family, social and potentially coworker interaction. She should see someone to be accurately diagnosed and discuss treatment options ...Read more

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What vaccines should my baby at for her 2 month check-up?

What vaccines should my baby at for her 2 month check-up?

2 month vaccines: vaccines given at 2 months old are:titis DTaP (diphtheria, tetanus, acelluar pertussis) PCV13 - pneumococcal conjugate Polio Hib - haemophilus influenzae type b Rotavirus hepatitis B Rotavirus is a oral vaccination. The others are given as shots. There are combination vaccines available as well. Discuss with your pediatrician what vaccines will be given at your child's check-up ...Read more

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Can a woman still be pregnant after her 2 week pregnancy test was false?

Can a woman still be pregnant after her 2 week pregnancy test was false?

Time and technique: Two weeks after what? It is better to wait 4-5 days after the missed period to do home pregnancy test; use first morning urine and follow the instructions carefully. ...Read more

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Can you tell me about estrogen and progesterone positive, her 2 positive - chance of being brca?

Can you tell me about estrogen and progesterone positive, her 2 positive - chance of being brca?

Breast cancer: HER2 positive means a protein in breast cancer cells promote cancer in breast and non breast tissues. you could inherit the bad cancer gene. this is an aggressive breast cancer. the standard chemo are not effective. new drugs are effective. estrogen & Progesterone are female hormones, but estrogen is more involved. chances are strong for HER2+ females to get cancer. ...Read more

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My niece is 3 months preg...Goin to a beach, but ? Is..Is it safe 4 her 2 go "tubing" if boat goes slower 4 her?

My niece is 3 months preg...Goin to a beach, but ? Is..Is it safe 4 her 2 go "tubing" if boat goes slower 4 her?

Stop her: I've seen too many "tubing" mishaps to recommend this. Sure it's safe at low speeds...And if you don't flip...And if you don't ram into anything...And if you don't accidentally run over something....(the list goes on & on). No one - no one goes slow while tubing, even if granny's turn is next.Trust me, pass on the tubing & i can guarantee no regrets should something happen. Stay safe my friends... ...Read more

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My daughter is prescribed Zantac (ranitidine) 2.5 ml bid. She only needs its at night. Do i give her 2.5 ml or 5 ml?

My daughter is prescribed Zantac (ranitidine) 2.5 ml bid. She only needs its at night. Do i give her 2.5 ml or 5 ml?

Ask your doctor.: Zantac (ranitidine) is most typically prescribed 2-4 times daily. For children, the doses are both age and weight dependent--and also depending on the diagnosis that triggered the use of this prescription. There are too many variables to accurately answer your question in this healthtap format. Please call your doctor and pose the question as you have done here. Great question! but ask your doctor.... ...Read more

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