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Doctor insights on: Hepatitis C And Pegylated Interferon

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Interferon (Definition)

Interferons are a diverse group of proteins that belong to a class of glycoproteins known as cytokines. Interferons were first discovered for their ability to block viral replication within host cells. They also have been found to activate immune cells for many disease processes. There are several classes of interferons, types i, ii and iii, depending on ...Read more


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What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

What are interferon alpha-2a and pegylated interferon alfa-2a (pegasys)?

2 versions 1 drug: They are the same drug except that the pegylation makes that drug longer acting, so it can be given less often. ...Read more

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Can sovaldi and Ribavirin cure hep c???

Can sovaldi and Ribavirin cure hep c???

Yes: It can...but better still Harvoni has a 96% cure rate with 8-12 weeks of treatment with minimal side effects. ...Read more

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What treatments for hepatitis C and hepatitis b?

What treatments for hepatitis C and hepatitis b?

Complicated: New and more effective treatments available. Oral meds for hep b; currently oral meds plus interferon injection for hep c. Complicated details depending on genotype, viral load, level of liver tests, markers, liver biopsy findings. Talk with your doc. ...Read more

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Can pegintron and ribavirin tx for hep c cause neurological tics?

Yes: Interferon can cause neurotoxicity. If you have new neurological symptoms, you should notify you doctor immediately for evaluation. ...Read more

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What is the difference between hepatitis C viral load and hepetitis c genotype?

Numbers and type: Viral load refers to how many viral molecules can be detected in the blood. It gives an idea about how active the virus is and can be used to monitor response to therapy. Genotype refers to a test that can identify subtypes of hep c. Certain genotypes are more likely to respond to a given therapy, so this information can be useful in deciding in what treatment, if any, would be best. ...Read more

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Is hep c curable?

Yes: There are multiple newer medications available to treat C. now, which can cure the disease. They are generally oral medications, taken for 8 to 24 weeks, and have greater than 90% success rate in curing the disease. They have very few side effects, although they are very expensive. If you have risk factors, be sure to get tested. Good luck! ...Read more

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Acute hep vs hep c positive: which one is worse?

Dead friend is worse: Death is generally considered worse than no death. There are effective therapies for chronic hep c available today. ...Read more

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Currently on victrelis (boceprevir) for hep c tx. How often are blood labs recommended?

Currently on victrelis (boceprevir) for hep c tx. How often are blood labs recommended?

Ask your Hepatologis: First of all, you should not be on victrelis (boceprevir) alone. It is given for only 12 weeks in addition to standard therapy with Ribavirin and interferon. Your hepatologist should discuss treatment duration, frequency of office visits as well as frequency of blood testing before you begin therapy. I suggest you contact your prescribing physician as soon as possible. ...Read more

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Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Hepatitis c injection" peg intron (peginterferon alfa 2b) a" has many side effects. How can they be decreased.?

Tylenol (acetaminophen) / Benadryl: You can try premedicating with tylenol (acetaminophen) and benadryl. Alternate injection sites. Get plenty of rest. ...Read more

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Hepatitis b and c with low platlet count?

Hepatitis b and c with low platlet count?

Cirrhosis ...: You need to contact your doctor pronto. When your platelets start dropping your liver may be decompensating meaning not functioning as well as it could. You could develop bleeding complications. ...Read more

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Is taleprevir better than boceprevir in the treatment of hepatitis C genotype 1?

Is taleprevir better than boceprevir in the treatment of hepatitis C genotype 1?

Hard to say: There are no head to head studies; an look at relative ratios suggests that telapravir may be somewhat more efficacious, but it did not meet statistical significance. Both are vastly better than interferon alone for genotype 1 hcv treatment. ...Read more

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HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative.  Need any medication or vaccine?

Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more

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Chronic hepatitis C do solvadi and ribavirin cause liver pain?

Chronic hepatitis C do solvadi and ribavirin cause liver pain?

No: Liver pain is generally not a frequently cited side effect of either of these medications. The sustained response rate for Sovaldi with or without ribavirin is 90+ percent for most of the common types of hepatitis C. You should discuss this with your gastroenterologist. Good luck. ...Read more

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Is there a treatment for hep virus c cirrhosis?

Is there a treatment for hep virus c cirrhosis?

Yes: The full answer is yes and no. The treatment depends on multifactos including type of hepatitis c, stage of cirrhosis. Treatment option varies. It could be from medication alone or transplant in selected cases. ...Read more

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Are interferon and peg-interferon different?

PEG interferone: Peg (pegylated) interferon is a long acting interferon, used to treat hepatitis b and c. Interferons are proteins released in the body in response to viral infections. Interferons are important for fighting viruses in the body, for regulating reproduction of cells, and for regulating the immune system. ...Read more

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So, which hepatitis C genotype is the worse?

So, which hepatitis C genotype is the worse?

Genotypes 1: Genotypes 1a and 1b are the most common in america, and have proven to be the more resistant to treatment. New treatments are on the way. ...Read more

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Dr. Robert Rahimi
581 doctors shared insights

Hep C (Definition)

A viral infection that effects the liver that can result in chronic disease, liver failure, and ...Read more


Dr. Camilla Graham
769 doctors shared insights

Hepatitis C (Definition)

An infection caused by a virus that attacks the liver ...Read more