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Doctor insights on: Hepatitis B Titer Non Reactive

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What does the titer result for hepatitis b surface ab test mean?

What does the titer result for hepatitis b surface ab test mean?

Marker of immunity: Surface ab is either a response to hep b infection or to injection of hep b vaccine. The titer indicates how much antibody is present in the blood. This level varies with time during the course of infection or following an injection. ...Read more

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Dr. William Forsythe
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Dr. Jay Park
1,077 doctors shared insights

Hepatitis (Definition)

Hepatitis is an inflammatory condition of the liver. Almost all cases are caused by viruses, including most commonly hepatitis a, hepatitis b, and hepatitis c, or by toxins (eg alcohol). The liver swells, it doesn't work properly leading to a failure to detoxify some biochemical substances, and a failure to excrete bilirubin, leading to jaundice. Some cases are fatal, ...Read more


Dr. William Forsythe
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If someone gets all three hepatitis b vaccines and a titer still indicates no immunity, what does this mean?

If someone gets all three hepatitis b vaccines and a titer still indicates no immunity, what does this mean?

Hep B non-responders: 5-15% of people do not develop the appropriate antibodies following the 3 vaccine series for Hepatitis B. If the series is repeated and there is again no response (30-50% of people WILL respond after a second series), the person is considered a 'nonresponder'. Nonresponders should be counseled about Hep B transmission and offered HBIG if exposed. ...Read more

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What happens if someone gets all three hepatitis b vaccines but a titer still indicates no immunity. what does that mean?

What happens if someone gets all three hepatitis b vaccines but a titer still indicates no immunity. what does that mean?

Boost It: Usually that means you need an additional dose of vaccine. Give the vaccine then check titers 6-8 weeks later and see if they are present. ...Read more

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Can you tell me if someone gets all three hepatitis b vaccines but a titer still indicates no immunity. What does that mean?

Can you tell me if someone gets all three hepatitis b vaccines but a titer still indicates no immunity. What does that mean?

Vaccine : Vaccine failure. I had similar response. 5 to 15 % do not respond (vaccine non responders). Your doctor can test you for hepatitis and if negative start another series of vaccines ...Read more

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I checked my hepatitis b titer , it is 800 so do I need to take still hepatitis vaccine?

I checked my hepatitis b titer , it is 800 so do I need to take still hepatitis vaccine?

More info needed: If you have not had any HBV vaccine and your anti-hbs antibody is positive, you've had the infection (and the anti-hbc antibody is positive too). No vaccine needed. If you are in the midst of a 3 dose HBV vaccine series and your anti-hbs is now positive, finish the series. It will provide better protection. ...Read more

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Dr. William Forsythe
Board Certified
21 years in practice
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Please explain what does it mean when you get hepatitis b (all 3 series) vaccine but titer still shows no immunity?

Please explain what does it mean when you get hepatitis b (all 3 series) vaccine but titer still shows no immunity?

Not immune: Some people don't get immune after getting the vaccine. You may need to get repeat vaccination, but some people just don't build the antibodies for protection. ...Read more

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What does it mean when you get the hepatitis b vaccine (all 3 series) but titer still shows no immunity?

Nonresponder?: People who do not mount immune response following a primary 3 dose series should have the entire series repeated. Inappropriate dose /admininistration, chronic disease and habits can can cause this. ...Read more

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I have to get a hepatitis b titer because the time frame of my hep b series. What does the titer procedure consist of? Also, should my results be okay

I have to get a hepatitis b titer because the time frame of my hep b series. What does the titer procedure consist of? Also, should my results be okay

Lots of people...: Lots of people get their hep b titers done. It is a simple blood test (just like getting a cholesterol test). The advantage of getting the titer done is that the titer will indicate whether or not booster vaccinations are needed now. If the titer is too low, booster shots are usually needed, regardless of the timing of the shots in the past. ...Read more

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The length of time between my hepatitis b series was greater than when each were supposed to be taken (now need titer).Were all shots still effective?

The length of time between my hepatitis b series was greater than when each were supposed to be taken (now need titer).Were all shots still effective?

Probably effective: If one is doing a blood titer test, the result will decide if she is immune or not immune. The shot schedule in the past won't matter anymore. Everybody with close or frequent contact with a hep b carrier (especially healthcare workers) should have their titers tested. Some people who get the shots at exactly the recommended time can still have very low titers, and need additional booster shots. ...Read more

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Dr. Anne Larson
963 doctors shared insights

Hepatitis B (Definition)

Hepatitis b is a viral liver disease. Until vaccines were developed this was a very common cause of hepatitis, and still is in some countries. Hep b is a progressive chronic disease which can lead to cirrhosis and also to cancer of the liver. It is also implicated in the causation ...Read more


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Dr. William Forsythe
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