Doctor insights on:
Hepatitis B Immune Globulin Medication
How small is the so called "small" risk of acquiring something bad from hepatitis b immune globulin (hbig) used as HBV pep (blood-derived product)?
Very very small: Modern treatment of Immune Globulin products has pretty much eliminated fear for hepatitis or hiv. However one is always concerned over prion which is a particle not degraded by alcohol or heat and can cause a severe neurologic condition. However I have not heard of a single case of this condition induced by immune globulin. Thus there is a risk which is as remote as being struck by lightning. ...Read more
Depends on dose: Immunoglobulin preparations are not checked if they have protective level antibodies anti-hepatitis a. Assuming that most blood donors have enough antibodies anti-hepatitis a, the immunoglobulin preparations should also have enough to neutralize a potential infection. However, this is especulation and it is possible that there could be enough viruses to overcome the neutralzing antibodies received. ...Read more
Every donor screened: Every time.Get a more detailed answer ›
All donors screened : Regardless of who they serve.Get a more detailed answer ›
If a person gets vaccine/immunoglobulin for Hepatitis B without first being tested for if they had it in the past, can any future tests show whether they had Hep B in the past? Can they find out if they had it in the past even if it didn't become chronic?
When is the latest, post exposure, that the Hepatitis B vaccine and immunoglobulin can be given to prevent infection? Is 13-18 days too late?
Worth a try: if you have never had hep B vaccine and susceptible . this is still a option if exposed, sooner rather than later, You should have blood test to check you hep B status before the two shots ...Read more
When is the latest, after exposure, that the Hepatitis B vaccine and immunoglobulin can be given to prevent infection? Is 13-18 days too late? Will getting the vaccine prevent you from being able to accurately test whether an infection occurred?
Are there any serious risks or possible side effects from getting Hepatitis B immunoglobulin? Can anything bad be transmitted through the blood from it?
HBIG: Most serious side effect with the injection of any medicine or biologic product would be anaphylaxis. Rare but possible. Since HBIG is derived from donor serum there could be potential for transmission of infectious disease, but such products are rigorously screened for all reasonable pathogens. Risk of Hep B is far far far greater than either of these. ...Read more
IVIg, SCIg: Immunoglobulins are proteins that aour body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
Yes: About 95% of otherwise healthy adults who are exposed to hepatitis b will control the infection with their own immune systems. The hepatitis b (hbv) is hiding in their liver cells, but usually stays dormant. These people will not have problems with hbv unless their immune system is severely compromised (like with cancer chemotherapy). ...Read more
Uncomfortable: Not sure what you mean or whether it is related in any way to your liver. Discuss with your doctor. If you have UC there are numerous potential complications. ...Read more
Complicated : Hep b serologies must be interpreted with caution Some doctors can misinterpret. An immune individual that received a vaccine has (HBV sAb+ , HBV sAg-, HBV core IgG Ab-). Resolved infection (HBV sAb+, ag-, core IgG+). Active infections / chronic infections are always surface antigen positive. If you need help consult me on my prime account ...Read moreSee 1 more doctor answer
Theoretically: It should. But as always it is wise to take measures to minimize risk for blood borne diseases regardless of vaccination status. ...Read more
Doctor said that i'm immune to hepatitis b, which is good. This is obviously from being vaccinated? (twinrix 3 injections). Am i 100% safe from hep b?
Likely: You are nearly 100% immune but there is always a possiblity of losing the immunity. If the doctor thinks that you are immune to hepatitis b is because you were tested for the hb surface antibody and it was present indicating that you are still immune. Precautions should still be taken as necessary and necessitated. ...Read moreSee 1 more doctor answer
Yes, but: prophylactically, meaning that you get the vaccine prior to getting infected. If infected, you will need the treated, taking chances isn't an option, wish you well ...Read more
How long does the Hepatitis B vaccine last & if you get the vaccine does that make you 100% immune from getting Hep B?
If a father has a hepatitis b, and the mother is immune to the virus, does the baby get any more hepb shots than a baby with normal parents?
The course is: Three doses over six months. As long as one develops the protective antibody (anti-hbs), one is immune. It is known that the antibody levels wane over time but it appears that immunity lasts longer than detectable antibody. But unclear if it is lifelong. ...Read moreSee 1 more doctor answer
How many times must one get vaccinated in their lifetime to be successfully immune hepatitis b virus?
Usually Once: The hbv vaccine is a series of 3-4 shots over a 6 months time period. At least 90% of people will develop immunity following that series. A portion of remaining people will respond to a second series. There is a very small group who do not develop immunity from vaccination. Booster shots are no longer recommended for people with normal immune status who have been fully vaccinated. ...Read more
No difference: No difference.Get a more detailed answer ›
What happens if I'm Rh negative and my b/fs Rh negative do I still need the micrhogam (rho immune globulin) shot?
No: No if you are both Rh- then the baby will be negative as well. If however, you had a child previously with a different partner who was Rh+ and the baby was also Rh+ then you might need one just to be safe. You should discuss this with your OB. ...Read more
Blood tested and I am not immune to Hepatitis B. Does that also mean that I don't have Hepatitis B or is that a different test?
IVIg, SCIg: Immunoglobulins are proteins that our body produce with the major function of neutralizing microbes. They are also called antibodies. Some people are congenitally deficient and receive a concentrate of immunoglobulins prepared from blood donors. When given intravenously is called ivig, given subcutaneously is scig. Another function is anti-inflammation, and is used in autoimmune conditions. ...Read more
Tetanus immune: globulin is used for treatment of tetanus, whereas a "tetanus shot" generally refers to the vaccine or immunization given preventatively ahead of time to children and adults. The immunoglobulin can also be given to try to prevent tetanus by giving it at the time of a wound with risk for tetanus. The vaccine is also given at that time, if the person does not have an up-to-date vaccine. ...Read more
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