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Doctor insights on: Hepatitis B Antigen Vs Antibody

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Antigen (Definition)

Antigens are chemicals which upon exposure to the surface or inside of the body, will cause a reaction term allergic. Many substances will do this and allergic response is the basis for immunological protection for ...Read more


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I have hepatitis b antigen positive, I am worried about getting married?

I have hepatitis b antigen positive, I am worried about getting married?

Ask Partner: If 1 partner, they vaccinated against hepatitis b? In this high risk situation have they considered having their immunity checked via blood work? Have you ruled out other sexually transmitted diseases such as hiv, hepatitis c, & other possibilities in yourself?
Use barrier methods--condoms independent of whatever birth control your partner may be using to protect both of you from transmission of std. ...Read more

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Might it be possible that a person having hepatitis b antigen negative donate blood?

Need more info: Which hep b antigen are you talking about? If it is hep b e antigen negative and you have positive viral load, then absolutely not. If it is hep b surface antigen negative, you have no viral load and have never been exposed to hep b, then yes. However, if you have had a w/u for abnormal liver enzymes despite negative hep b, you will likely be rejected as that is 1 of the screening questions. ...Read more

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Hepatitis b antigen negative HBV load is 13160iu/ml. Taking tenofo b for three months now HBV load is >20. Please suggest me what can I do?

Hepatitis b antigen negative HBV load is 13160iu/ml. Taking tenofo b for three months now HBV load is >20. Please suggest me what can I do?

Continue to take: You are a hepatitis B virus carrier. With the use of the antiviral agent, tenofovir, you have successfully suppressed viral replication, which will help reduce the risk of hepatitis progression. This does not mean that you are cured however, and you will need to take this medication, as prescribed, otherwise you are at risk for viral reactivation and developing a drug resistant mutation. ...Read more

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What's a hepatitis b antigen?

What's a hepatitis b antigen?

Coat protein: There are a number of antigens associated with hbv, notably surface, core, e, and x. The surface antigen, hbsag, is the surface coat of the virus and the most commonly tested for. ...Read more

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What to do about hepatitis b antigen, hep b core IgM - acute or chronic?

What to do about hepatitis b antigen, hep b core IgM - acute or chronic?

Hep B: Hep B core IgM antibody is only present in acute infection. The IgM will then be lost, and you develop Heb B core antibody total (IgG) that persists for life. After acute infection, one hopefully loses the surface antigen and develops surface antibody, which indicates lifelong immunity. The surface antibody also persists for life. If persisting surface antigen, this indicates chronic infection. ...Read more

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Medical reports of my father having alfafetoprotein (afp) is 11727.28 ng/ml, hepatitis b antigen 78.05 & HBsAG is >250iu/ml what is meant by report?

Medical reports of my father having alfafetoprotein (afp) is 11727.28 ng/ml, hepatitis b antigen 78.05 & HBsAG is >250iu/ml what is meant by report?

Elevated AFP: Given your father's history of chronic hbv infection and now with the marked elevation of afp, this is almost conclusive of possible hepatocellular carcinoma. Need to follow up with your primary care doctor, gi, and oncologist for further work up and definitive treatment. ...Read more

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My father (age : 61) is tested reactive on hepatitis b antigen. Is there any side-effect for him to take salmon oil & lecithin to lower cholesterol?

My father (age : 61) is tested reactive on hepatitis b antigen. Is there any side-effect for him to take salmon oil & lecithin to lower cholesterol?

Lower cholesterol: Unless there is an allergy or sensitivity, salmon oil and lecithin should be perfectly safe to ingest in moderate amounts. ...Read more

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Test result was "Hepatitis Surface Antibody - Nonreactive" and "Hepatitis B Surface Antigen - Reactive", "HBS AG Confirmation - Nonconfirm".

Test result was "Hepatitis Surface Antibody - Nonreactive" and "Hepatitis B Surface Antigen - Reactive", "HBS AG Confirmation - Nonconfirm".

Hmmmm: Got me beat. A reactive Hep B antigen indicates that you have Hepatitis B. However, It looks like the test was NOT confirmed. My experience with labs is that their report format could use some improvement and you may be misreading this. Talk to the doc who ordered the test. ...Read more

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What does it mean if "HEPATITIS B SURFACE ANTIBODY QL" is "borderline" but "HEPATITIS B SURFACE ANTIGEN" is "non-reactive"?

What does it mean if "HEPATITIS B SURFACE ANTIBODY QL" is "borderline" but "HEPATITIS B SURFACE ANTIGEN" is "non-reactive"?

Uncertain.: Without the rest of your lab values, it is difficult to know for sure. These value suggest that you may have been exposed or vaccinated for hepatitis B in the past, but again we're working with incomplete information. You may speak with your physician who ordered the tests or call us at HealthTap Prime if you have the rest of the results. Good luck. ...Read more

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I had blood tests done and my hepatitis b surface antibody QL reactive, hepatitis b surface antigen non-reactive, what does it mean?

Need entire panel.: You're best off using HealthTap Prime to answer your question. You can upload the entire lab report & discuss with a doctor. So far, test shows you have antibodies but no antigen: means either you're in the "window period" after exposure when the virus goes "underground" or you were given a vaccine which made you immune to hepatitis B. We need the pre-core "e" test. Use HealthTap Prime to disucss. ...Read more

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hepatitis b surface antigen reactive and hepatitis b surface antibody nonreactive and core antibody total reactive and HBV DNA detected sir plz reply?

hepatitis b surface antigen reactive and hepatitis b surface antibody nonreactive and core antibody total reactive and HBV DNA detected sir plz reply?

You carry hep B: I am assuming you feel well and this was a surprise finding. There are millions of people like yourself. You will require lifelong health care for it unless / until a means of eradicating it is found. You pose no danger to a partner who is immunized. ...Read more

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IMy HBV test results (red cross): Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Do I have HBV?

IMy HBV test results (red cross): Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Do I have HBV?

Cured, but...: If a person's Hep B surface antigen is nonreactive, that means the lab does not find pieces of the surface of the virus. If her Hep B virus PCR is negative, that means the lab does not find the virus's DNA (genes). If the core antibody is reactive that means her immune system REMEMBERS being infected with Hep B. She is cured, but some viral DNA might be attached to her own human DNA in her liver. ...Read more

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HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

Excellent question: And your story stumps many a doctor, often! :)
a lot of the recommendations depend on - are you someone with risk factors for HBV? Is this the first time that it has been checked? Are your liver enzymes normal? Are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more

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What is hepatitis b surface antigen in general?

What is hepatitis b surface antigen in general?

Infection is active: If you are surface antigen postive = protein on the surface of the virus is in its active form which is still floating in your blood and indicates active/on going infectious state. This protein triggers body to produce antibody which can help rid off the infection or preventing it as in case of hepb vaccines. In your case, no antibody or not enough to rid of the antigen. Consult doc. Good luck. ...Read more

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Help please? What is the hepatitis b surface antigen?

Hepatitis B: If you have a positive hepatitis B surface antigen, then you have active hepatitis B infection. You can see a hepatologist (liver doctor) to check some other labs in order to determine if you need to be on treatment with oral medications or if a liver biopsy should be considered based on other laboratory results. Having hepatitis B can be controlled with medications. ...Read more

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Wondering if hepatitis b e antigen reactive can be cured?

Wondering if hepatitis b e antigen reactive can be cured?

Yes and no: It's possible to convert from e antigen (hbeag) to e antibody (hbeab) with treatment of hepatitis b. This is a good thing, as it means your hepatitis is less active and you are less infectious to others. However, hepatitis b itself is not considered to be 'curable, ' and conversions from surface antigen (hbsag) to surface antibody (hbsab) rarely happen. ...Read more

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What if the hepatitis b surface ab antibody is positive?

Protection against..: Detection of antibody against hepatitis b surface antigen means the host is successfully immunized or recovered from hep b infection and therefore, is protected from getting infected with hepatitis b. ...Read more

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If you don't have hepatitis b and you are given the hepatitis b antibody vaccination, what could happen?

If you don't have hepatitis b and you are given the hepatitis b antibody vaccination, what could happen?

It's a start.: If you finish out the series by getting another dose in a month and a third dose at 6 months, then you will be immune to hepatitis B for life. Go for it. ...Read more

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Hepatitis b surface antigen non-reactive means what?

No active infection: When people have reactive hepatitis b surface antigen, they have proteins from hepatitis b in their blood. These people have active infection and may need treatment. If there is no reactive hbsag, then most likely there is no active infection. Rarely, people who have hepatitis b core antibody detected, but no hepatitis b surface antibody, can have chronic active infection. ...Read more

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What is hepatitis b surface antibody telling you?

Depends: ...If you have anti-hbs alone without anti-hbc, it means immunization. If with anti-core, it means previous infection. ...Read more

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Hepatitis b core antibody, positive, . Am I safe from hepatitis?

Hepatitis b core antibody, positive, . Am I safe from hepatitis?

Exposed in the past: If the hepatitis b core antibody (igg) is positive it means you have been exposed to the virus. It does not give information regarding if the virus is active or not. Other blood tests give us this information. ...Read more

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Is it possible for the hepatitis b surface antibody to go from reactive to nonreactive?

Is it possible for the hepatitis b surface antibody to go from reactive to nonreactive?

Yes: It is possible though the clinical consequences of the change is not entirely clear. One may still harbor immunity. ...Read more

Antibody (Definition)

An antibody is a protein the body's immune system makes to identify potentially harmful substances in the body. Antibodies attach to the substance on a molecular level and mark it so the immune ...Read more


Dr. Anne Larson
1,058 Doctors shared insights

Hepatitis B (Definition)

A serious liver infection caused by the hepatitis B virus that's easily ...Read more