Top
20
Doctor insights on: Hepatic Fibrosis In Children

Share
1

1
What's it mean to have hepatic fibrosis?

What's it mean to have hepatic fibrosis?

Fibrosis = scarring: Inflammation of the liver, as almost anywhere else in the body, often heals with scarring. Lose enough functioning liver cells to scarring & you get cirrhosis. A fibrosis score is typically calculated during liver biopsy (& some fancier liver imagings) to calculate how much damage a chronically inflammed liver has sustained, & its risk of failing /decompensating. Then you need a liver transplant. ...Read more

Hepatic (Definition)

Hepatic refers to something that is ...Read more


2

2
What are the tests for hepatic fibrosis?

HepaScore: If not liver biopsy, alpha2 macro globulin increase; a lipoprotein a1 decrease, ggt, bilirubin, hyaluronic enzyme immunoassay; sex and age factor in as well. ...Read more

3

3
What are the symptoms of hepatic fibrosis?

What are the symptoms of hepatic fibrosis?

None: Fibrosis is scarring as a result of inflammation and tissue damage. Eventually the scarring isolates pockets of hepatocytes (liver cells) so that they can no longer function appropriately. This is cirrhosis, and that creates problems resulting in symptoms. ...Read more

6

6
Liver biopsy = hepatic parenchyma showing moderate to severe chronic hepatitis w/bridging fibrosis &focal changes of early micronodular cirrhosis. Grade 3-4 stage 3-4. Can thyroid cause this? Or what?

Liver biopsy = hepatic parenchyma showing moderate to severe chronic hepatitis w/bridging fibrosis &focal changes of early micronodular cirrhosis. Grade 3-4 stage 3-4. Can thyroid cause this? Or what?

No: Thyroid problems do not cause cirrhosis. You may have an autoimmune hepatitis leading to cirrhosis, which could be associated with thyroid disease.
There are many causes of cirrhosis, ask your doctor to test you, as most can be checked with a blood test. ...Read more

7

7
What is cystic fibrosis in children from?

What is cystic fibrosis in children from?

Recessive gene: A mutation is carried in the dna of both unaffected parents & that matching or similar mutation is paired up at conception when the sperm & egg form completed chromasomes with the defective info. Late in pregnancy and after delivery, the effect of the CF gene abnormality begins to reveal itself. In carriers, the good gene compensates for the bad & no problems occur. ...Read more

8

8
Can people with cystic fibrosis have children?

Can people with cystic fibrosis have children?

Women can: Men are infertile, but woman can have children, at a serious risk to their health. ...Read more

9

9
How to treat fibrosis post surgical in children?

How to treat fibrosis post surgical in children?

Can try...: Topical verapamil cream to help reduce fibrosis after surgery. Ask your doctor for a prescription - a good combination is verapamil 10% with diclofenac 5% in transdermal cream. ...Read more

10

10
Is it possible for men with cystic fibrosis to still have children?

Is it possible for men with cystic fibrosis to still have children?

Yes but note:: 1. Cystic fibrosis may affect male fertility through a. Thick viscid semen b. Association with absence of the vas, the tubes that conduct sperm from testes to outside. Thick sperm can be easily handled with iui. Obstruction can be addressed through harvesting sperm from the testes and using it for ivf. 2. Genetic consideration: there is a risk of transmission of CF to children-genetic counseling. ...Read more

11

11
How much time to people with cystic fibrosis live and can it be passed to children?

How much time to people with cystic fibrosis live and can it be passed to children?

Start with this link: The short answer is that CF is genetically passed on to children through inheriting a CF gene from both the mother and the father.
Start with information here:
http://www. Cff. Org/aboutcf/ ...Read more

12

12
Can men with atypical cystic fibrosis have children? I have 2 children, I have no symptoms of CF and I am 32 years old. Never tested for CF.

Can men with atypical cystic fibrosis have children? I have 2 children, I have no symptoms of CF and I am 32 years old. Never tested for CF.

Sometimes: Actually, there are several different reasons that men with classic cystic fibrosis tend to be infertile; CFTR is part of the molecular machinery of spermatogenesis. It depends on your mutation. I'm wondering what you're worried about. Best wishes. ...Read more

13

13
Can pulmonary fibrosis affect young children?

Can pulmonary fibrosis affect young children?

Unusual: Rarely in presence of connective tissue disorders, after certain medications, after chest radiation. ...Read more

14

14
If you mother is a carrier of cystic fibrosis is it posibble for one of her children to get it in there audlt years.?

If you mother is a carrier of cystic fibrosis is it posibble for one of her children to get it in there audlt years.?

Not going to happen: The predominant forms of CF (70%) come from inheriting a delta f508 mutation from both parents. If the biological dad does not carry a CF gene, delta f508 or any of the dozens of similar minor mutations, the kid cannot suddenly develop CF. Carrier detection is available to test any potential parent, and many suggest people know the status of both if one is a known carrier. ...Read more

15

15
My partner has cystic fibrosis (male) and I have children 3 boys to a previous relationship. I'm desperate to know if it possible to have iui?

My partner has cystic fibrosis (male) and I have children 3 boys to a previous relationship. I'm desperate to know if it possible to have iui?

Yes: Of course. Question is whether you are looking for a donor. If so california cryobank takes great care in helping people like you. I'm not sure that IUI with your husbands sperm is a good idea. Check me on this but if you do not carry the gene (1:26 for caucasion, carrier rate) your children may be carriers without the actual disease. Look it up and see geneticist, I'm going off top of head. ...Read more

16

16
How can cystic fibrosis affect p.I.E.S development?

How can cystic fibrosis affect p.I.E.S development?

Certainly: Cystic Fibrosis (CF) most common life-limiting genetic disorder of Caucasians, affecting approximately 30K people in the US. A, impacting mainly respiratory function. In recent years patients symptoms better controlled by genetic findings and better medications. Emotional & phys. Development depend on severity, time in hospital, complications. Morb. & mort. Factors afect emotional, cognitive behavior. ...Read more

17

17
Can someone be diagnose with cystic fibrosis in their 40's?

Can someone be diagnose with cystic fibrosis in their 40's?

As a carrier: Genetic carrier testing:
more than 10 million americans are symptomless carriers of the defective CF gene. This blood test can help detect carriers, who could pass CF onto their children. To have cystic fibrosis, a child must inherit one copy of the defective CF gene from each parent. ...Read more

18

18
I have symptoms of cystic fibrosis. Is it possible to start show the symptoms in my 30's?

Yes: Yes it is possible. Presentation of cystic fibrosis varies greatly, and it is possible, depending on your specific mutation (and other factors) to present at a later age. In order to prevent late diagnoses, all states now have a newborn screen in place for cystic fibrosis. ...Read more

19

19
I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

I have family members with cystic fibrosis. Is it possible to start show the symptoms in my 20's?

Yes: However, usually an adult who is diagnosed so late has usually had chronic problems with cough and "pneumonias". That said I've diagnosed a new case in a 38 year old woman. ...Read more

20

20
What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

What are the chances of a child getting cystic fibrosis among the different racial groups in the u.S.?

Overall 1/3700: Acording to the CF foundation: the overall birth prevalence is 1/3700. It can occur in any race, however the greatest incidence is in caucasians of northern european descent, being 1/2500. The other major groups affected are hispanics 1/13500, african americans 1/15000.
More than 10 million of us carry one part of the defective gene, but to have the disease you must have a copy from both parents. ...Read more

Dr. Ira Friedlander
8 Doctors shared insights

Hepatic Fibrosis (Definition)

There is excessive connective ...Read more