Heparin bladder instillation - Doctor answers
Do the bladder instillation treatments of heparin, bicarbinate of soda, and lidocane help bladder inflamation?
The bladder is a muscular organ in the pelvis that accepts urine from the kidneys, stores the urine at low pressure, & expels the urine during voluntary voiding. Though seemingly a simple reservoir, the bladder is a complex organ intricately connected with the brain and spinal cord with sensory, motor, and autonomic circuits. The muscular layer that contracts during voids ...Read more
Is it safe to use heparin that is two years old in an interstitial cystitis bladder cocktail? The heparin is in unopened sealed vials.
So i'll be receiving a heparin and lidocaine instillation next week and I'm concerned about possible side effects, should I be concerned?
Low molecular weith: Heparin is used as an anticoagulant. In low doses the intent is to prevent clotting. In full dose it is used to treat an established clot. If is given as a subcutaneous (under the skin) injection, which is more convenient than a continuous IV infusion of standard heparin. ...Read more
This is a myth: There is a lot of misinformation about Heparin and Lovenox (enoxaparin) out there. These are injectable blood thinners that can be helpful for women with recurrent miscarriage due to anti phospholipid syndrome - a type of lupus. It is currently not recommended for infertility or for recurrent miscarriage unless you have anti phospholipid syndrome. This is a new acog recommendation just this year. ...Read moreSee 1 more doctor answer
Restate question: The question does not make any sense. ...Read more
Two pathway measures:
The PT can be with VERY HIGH doses of heparin but generally remember our coagulation system has two primary enzymatic pathways measured differently in the lab
1. Intrinsic system :measured by aPTT (activatted partial thromboplastin time) and prolonged by heparin and
2. Extrinsic system: measured by PT (prothrombin time) and prolonged by coumadin (warfarin).They then converge at the final common pathway. ...Read more
HIT: HIT is known as heparin-induced thrombocytopenia. There are two forms. Only type II is clinical significant and can be life threatening if not recognized and treated appropriately. It is mediated by an immune mechanism through formation of antibodies against platelet. It occurs in 1-5% of patients exposed to heparin, regardless of the dose or route of administration. ...Read more