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Doctor insights on: Hep C Viral Rna Qual Pcr

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Hep c antibody rest reactive, qualitative RNA PCR says no RNA material found. Do i need further tests or i can relax that I have cleared. ?

Hep c antibody rest reactive, qualitative RNA PCR says no RNA material found. Do i need further tests or i can relax that I have cleared. ?

Mostly likely yes: This is wonderful news. Very rarely people can have fluctuately virus levels, so some people get checked one more time in around 4 months to definitively establish that they spontaneously cleared their hcv infection. ...Read more

Polymerase Chain Reaction (Definition)

Polymerase chain reaction is a method of finding a specific piece of dna and copying it over and over again until there is enough to study. The technique allows a scientist to detect very small amounts of dna in a swab sample then reproduce enough of it to study it. It is very sensisitive for detecting the presence of certain bacteria and is also used in doing other ...Read more


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I Had a blood test & everything negative except the hep c ab w/refl to hcv rna, qn, pcr signal to cutoff the result is <1.00 what does that mean?

I Had a blood test & everything negative except the hep c ab w/refl to hcv rna, qn, pcr signal to cutoff the result is <1.00 what does that mean?

This is a very: convoluted way of saying "this is a negative test." First the antibody that fights off hep C was checked. Because it may take up to 3 months for the antibody to show up, a second test, the HCV RNA, was checked automatically (i.e., reflexively or w/refl). The cut off value of <1.00 means that the virus itself could be NOT be detected either. Hope this helps! Dr. Anne ...Read more

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Hep c anti body 14 with cutoff of 1, but qualitative HCV RNA PCR says no RNA material detected. In notes says single test not enough . My alt, cbc, ok

Hep c anti body 14 with cutoff of 1, but qualitative HCV RNA PCR says no RNA material detected. In notes says single test not enough . My alt, cbc, ok

Probably cleared: The hcv viral load tests are not fda approved to confirm active infection, although this is how most doctors use it. If a repeat viral load in around 4 months is also negative, people are considered to have spontaneously cleared infection. ...Read more

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Is it safe to stay on Suboxone after being diagnosed with hep c? So far no lft abnormalities, but HCV antibody positive. Pending PCR and viral load

Is it safe to stay on Suboxone after being diagnosed with hep c?  So far no lft  abnormalities, but HCV antibody positive.  Pending PCR and viral load

Yes!: It is very safe--in fact, i would insist one of my patients stay on the suboxone especially if they were going to go through the interfuron therapy. It is bad enough trying to go off suboxone without having hepatitis or being on the interfuron! just make sure your doctor keeps up with your lft's. Good luck! ...Read more

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Hep c +, no viral load, RNA performed.Was told i cleared the virus 11years ago. In a new relationship. How do I explain this to my partner? Confused.

Hep c +, no viral load, RNA performed.Was told i cleared the virus 11years ago. In a new relationship. How do I explain this to my partner? Confused.

Hepatitis C Cleared: This means you were infected. But, you did not get the chronic or active infection. Clearing this infection means you are no longer contagious. ...Read more

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Hep C indeterminate result before 6+ months, 2 negative result within 6 months, 1 indeterminate last week. Doc will not do pcr test. Do I Have hep c?

Hep C indeterminate result before 6+ months, 2 negative result within 6 months, 1 indeterminate last week. Doc will not do pcr test. Do I Have hep c?

I say no: I'm sorry you can't get a definitive test. The old antibody assays gave many tests like this, and folks like you usually proved not to have the bug on board. Why not relax? You're not a significant danger to your friends, even possible romantic partners. I trust you're not sharing needles. I think Hep C will be easy to cure for almost anyone soon enough if you DO prove to have it. Best wishes. ...Read more

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If a person has hep c antibodies but a undetectable PCR is it gone or can it be in the body dormant? Can it reactivate?

If a person has hep c antibodies but a undetectable PCR is it gone or can it be  in the body dormant? Can it reactivate?

Either is possible: Positive anibody test for Hepatitis C indicates only oast exposure. Negative PCR means the virus is undetectable which means it is inactive for the time being but with no guarantee that it had completely disappeared ...Read more

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Hep c ab positive. Pcr non reactive. Am i contagious?

No: If you have a positive hcv antibody but a negative pcr, you most likely had hepatitis c at one time but cleared the infection, in which case you no longer have hepatitis and are not contagious. Talk to your doctor. ...Read more

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False positive hep c antibody tests? I have had 2 positive tests 1.04, 1.15 and one negative test. Also 2 negative PCR tests, 18 wks after needle stic

Hep C unlikely: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, give than Hep C pcr test was negative at 18 weeks after exposure, it is unlikely that you have Hep C infection. ...Read more

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Help, m, 57 in suspense, qualitative HCV PCR result after three days, hep c antibody at 14 (cut off of 1). Alt, serum albumin, protein, CBC all normal.

Result?: Your scenario reminds us that even if an hcv antibody test is positive, it is mandatory to check hcv RNA (viral load) to see if someone actually has active infection. About 25% of people will have spontaneously cleared infection soon after being exposed (and many people were exposed and cleared 20 - 30 years ago). ...Read more

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If u have hep c with no RNA (viral load) how come you're not infectious & no treatment needed? Thanks

Hep C testing: If you have no detectable hepatitis C virus -then you don't have the infection! The human body is capable of clearing out the infection in about 15% of people -by itself without any medicine. You probably have the Hepatitis C antibody showing in your blood. That is evidence your body 'saw' the virus and 'killed it' before any real damage was done. So this is GREAT NEWS! Congratulations! ...Read more

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Results: Hep C quant. : 2,802,680 HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Hepatitis C virus: Sometimes it's not possible to determine the genotype of this virus, which thus makes the expected response to treatment more uncertain. This is a 'slippery virus' -there are 11 major genotypes (designated 1-11), and many subtypes (a, b, c, etc.) A hepatologist (GI subspecialist) or an ID doctor who works with Hep C patients can help you. You'll need an established relationship for treatment... ...Read more

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If nurse made mistake(exposed to air or heat) taking blood, will that effect a HIV PCR RNA/VIRAL LOAD test?Negative result but worried. Pls help.

If nurse made mistake(exposed to air or heat) taking blood, will that effect a HIV PCR RNA/VIRAL LOAD test?Negative result but worried. Pls help.

No: Occasionally on the broadcast news, somebody will find human remains that have been in the jungle or in the desert for months or years... and the crime lab will identify who died, by using DNA analysis. Testing for RNA or DNA will reliably detect the RNA or DNA that is being looked for, if it is there. ...Read more

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Advia hep.C antibody +, HCV RNA -. 3 months later Architect hep C Ab -, HCV RNA -. 2 Hep C Ab Verification tests -.Is Advia hepC Ab test false positiv

Without more info: and only the data you submitted in your question, I would put it together the way you did: the first Advia hepC Ab test was a false positive. I presume other experts who arranged your follow-up testing have suggested the same interpretation. Stay well:) ...Read more

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Hep B Virus (HBV) DNA Qualitative (Detection) - COBAS TaqMan , Hep C RNA Detection by Taqman detection will be conclusive on 47 days? Any retest need?

Hep B Virus (HBV) DNA Qualitative (Detection) - COBAS TaqMan , Hep C RNA Detection by Taqman detection will be conclusive on 47 days? Any retest need?

No: Both Hepatitis B and C viruses may be detected 30 to 60 days after infection by antigen detection or 60-120 days with antibody testing. Direct HBV DNA and HCV RNA testing can potentially detect infection earlier, within 2-4 weeks after infection, so being tested at 47 days post-exposure with a negative nucleic acid test for both is very likely to be a true negative ...Read more

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Advia hep. C antibody +,HCV RNA -. 3 months later Architect hep. C antibody -, HCV RNA -. 2 hep C Ab Verification tests-.Can above person donate blood?

Advia hep. C antibody +,HCV RNA -. 3 months later Architect hep. C antibody -, HCV RNA -. 2 hep C Ab Verification tests-.Can above person donate blood?

May be: You ought to disclose these results to the blood bank so that they may make a determination on your eligibility to donate along with other health factors. I commend you for considering doing your civic duty. ...Read more

Pcr (Definition)

Polymerase chain reaction is used in molecular biology to amplify copies of dna. It is used in dna cloning for sequencing, functional analysis of genes, identification of genetic finger prints, diagnosis of hereditary ...Read more


Dr. Robert Rahimi
571 doctors shared insights

Hep C (Definition)

A viral infection that effects the liver that can result in chronic disease, liver failure, and ...Read more