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Doctor insights on: Hemosiderin

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Dr. K. Mujib Haque Dr. Haque
Internal Medicine
20 years in practice
St. George's University School of Medicine
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Hemosiderin stains from bruises, what do they mean? Is there something a little off?

Hemosiderin stains from bruises, what do they mean? Is there something a little off?

Excessive Bruising?: You know bruises change color after a few days? Hemosiderin is iron product in our blood. After a few days it becomes darker in color. What is more imprtant is if you are egtting lots of bruises with minor impact or injury. Check Platelets count, Prothrombin and Partial Prothromin Time. You you have any abnormal bleeding from gums or other sites? . Excessive bruising must be checked.

Dr. Landi Halloran Dr. Halloran
Internal Medicine
18 years in practice
Michigan State University College of Human Medicine
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What is meant by abundant benign appearing epithelial cells hemosiderin-laden macrophages and colloid present. Also scattered micro follicles noted?

What is meant by abundant benign appearing epithelial cells hemosiderin-laden macrophages and colloid present. Also scattered micro follicles noted?

It's good news: Sounds like you had a biopsy. I'm guessing thyroid. Epithelial cells, colloid, micro follicles all belong there and confirm an adequate sample was taken. No cancer cells are reported (good news!) hemosiderin laden macrophages can mean local bleeding, inflammation, or (rarely) that you store too much iron. Please ask your doctor about whether you should have your iron storage levels checked.

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Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
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Abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages and colloid present, favor adenomatoid nodule.?

Glad to hear it: Your thyroid nodule is benign. You may have several and they are probably benign as well. Nobody knows what causes these little adenomatous nodules, but they have very little tendency to turn bad.

Dr. Norman Chideckel Dr. Chideckel
Surgery - Vascular
38 years in practice
State University of New York Downstate Medical Center College of Medicine
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I have patchy brown/yellow discoloration on my lower leg, most likely hemosiderin deposits due to venous insufficiency. I'm 40; what can remove this?

I have patchy brown/yellow discoloration on my lower leg, most likely hemosiderin deposits due to venous insufficiency. I'm 40; what can remove this?

Stasis changes: You need an evaluation to determine the source of the varicose veins accomplishe dby venous doppler sonogram and then tratment to prevent worsening of the discoloration use support stocking until then

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Dr. Coyle Connolly Dr. Connolly
Dermatology
25 years in practice
Philadelphia College of Osteopathic Medicine
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Is there laser or bleach treatment for hemosiderin deposits under skin? Injection area is red. It can be up to several months but I need it gone sooner.

Is there laser or bleach treatment for hemosiderin deposits under skin? Injection area is red. It can be up to several months but I need it gone sooner.

Deposits: Hemosiderin is usually not responsive to bleaching creams or laser. The circulation abnormalities associated with this condition should be evaluated by a physician.

Dr. Ed Friedlander Dr. Friedlander
Pathology
40 years in practice
Northwestern University Feinberg School of Medicine
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Please interpret pericardium tissue mononuclear infiltrates with rare polymorphnuclear leukocytes & eosinophiles. Hemosiderin-laden macrophages.

Please interpret pericardium tissue mononuclear infiltrates with rare polymorphnuclear leukocytes & eosinophiles. Hemosiderin-laden macrophages.

Not tumor: This is the site of an old bleed and probably infection or physical injury. The key is that there's not tumor found. Any interpretation beyond this without a history would be meaningless.

Dr. Clarence Grim Dr. Grim
Internal Medicine - Endocrinology
53 years in practice
University of Missouri-Columbia School of Medicine
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Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy results Showing minute fragment of thyroid tissue w/ hemosiderin-laden macrophages & blood elements most consistent w/follicular lesion?

Thyroid biopsy: What is your question? Sounds to me like you have a lesion of the thyroid follicle. But they may have missed something else. Why was biopsy being done? Take to the Dr who did it as they know you best.

Dr. Sewa Legha Dr. Legha
Internal Medicine - Oncology
46 years in practice
Punjab University, Christian Medical College
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Fna, 2 nodules left lobe. Abundant benign appearing epithelial cells, hemosiderin-laden macrophages& colloid present. Scattered microfollicles noted. Path says can't entirely rule out fillocular lesio?

Fna, 2 nodules left lobe. Abundant benign appearing epithelial cells, hemosiderin-laden macrophages& colloid present. Scattered microfollicles noted. Path says can't entirely rule out fillocular lesio?

Is this Thyroid biop: It looks like thyroid nodules. This may be a fna biopsy report which is indeterminate. You need to follow your endocrinologists advice which will likely require excisional surgery for these lesions.

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Dr. Myron Arlen Dr. Arlen
Surgery - Oncology
60 years in practice
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What does this diagnosis mean, Left thyroid: cystic lesion with hemosiderin-laden macrophages. Its my cytology report from a thyroid nodule.

What does this diagnosis mean, Left thyroid: cystic lesion with hemosiderin-laden macrophages. Its my cytology report from a thyroid nodule.

Probable benign: Most cystic lesions and not pure cysts usually respresent breakdown and hemmorhage into a benign neoplsm. The presence of macrophages and hemosiderin suggest some form of inflammatory condition such as Hashimoto's thryoiditis. Unless there are changes on physical and thyroid scan suggesting further growth, conservtive management is suggested.

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Dr. Austin Yeargan III Dr. Yeargan III
Orthopedic Surgery
20 years in practice
Brody School of Medicine at East Carolina University
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Dr. Douglas Lake Dr. Lake
Radiology
15 years in practice
University of Kansas School of Medicine
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Two nodules, 1.9 and 1.8 CM on left thyroid lobe. 1st nodule is benign follicular. 2nd is abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages & colloid noted. Cancer?

Two nodules, 1.9 and 1.8 CM on left thyroid lobe. 1st nodule is benign follicular. 2nd is abundant benign appearing follicular epithelial cells, hemosiderin-laden macrophages & colloid noted. Cancer?

Not cancer: Both nodules sound perfectly benign by their histologic description. Sonographic (ultrasound) follow-up is recommended in 12 months to ensure stability.

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Dr. Chris Hawley Dr. Hawley
Family Medicine
20 years in practice
UCLA School of Medicine
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What does altered marrow signal in distal femur and proximal tibia accompanied with hemosiderin deposition & thickened synovium in MRI left knee mean?

What does altered marrow signal in distal femur and proximal tibia accompanied with hemosiderin deposition & thickened synovium in MRI left knee mean?

Hemosiderin MRI: This may be consistent with a condition of the knee called pigmented villodular synovitis. This is caused by inflammation of the lining of the knee joint (synovium) and resulting deposit of breakdown of blood products. The cause is largely unknown. The diagnosis of pigmented villonodular synovitis is confirmed by biopsy, and the treatment of choice is synovectomy.

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