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Doctor insights on: Hemophilia Blogs

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What is hemophilia?

What is hemophilia?

Clotting problem: Hemophilia is a hereditary blood disorder in which the person is deficient in one of the body's clotting factors (factor viii for hemophilia a and factor ix for hemophilia b). Therefore the blood does not clot correctly after an injury. Depending on severity, patients with hemophilia bleed and bruise easily and for a longer time. Some may even bleed into their joints, muscles, or brain. ...Read more

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Dr. Susumu Inoue
127 doctors shared insights

Hemophilia (Definition)

A hereditary disorder of clotting factors in the blood, ...Read more


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Is hemophilia lifelong? 

Yes: About 17, 000 people in the United States have hemophilia. The blood of a person who has hemophilia, a rare, inherited bleeding disease, lacks a protein important to proper clotting. Because it is inherteted at birth it is lifelong. ...Read more

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What causes hemophilia?

Genetic defect: Hemophilia is a bleeding disorder due to abnormal gene for clotting factor viii (hemophilia a) or ix (hemophilia b) that is on the x-chromosome and men inherit the defect from their mothers. Women are carriers and are rarely affected. ...Read more

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How is hemophilia treated? 

How is hemophilia treated? 

Hemophilia: The treatment of hemophilia depends on what type the patient has, how severely they are affected, and whether any surgical procedures are planned. Without knowing what type of hemophilia you are discussing i can't be more specific. A good source of information is the national hemophilia foundation at www.Hemophilia.Org. ...Read more

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What exactly is hemophilia?

What exactly is hemophilia?

Gene for bleeding: The two common hemophilias are lack of factor viii (hemophilia a) and factor ix (hemophilia b) respectively. Of variable severity, these people are prone to bleed too easily especially from blunt trauma. Treatment consists of replacement of the missing factor and is a complicated business with specialists that are well-equipped to do this. Cure by gene therapy may soon be here for ix. Good luck. ...Read more

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How is hemophilia inherited? 

How is hemophilia inherited? 

Hemo."A" is X-linked: Hemophilia "a" is a hereditary bleeding disorder where there is a deficiency in clotting factor viii (factor viii is needed for blood clotting). It is inherited on the x-chromosome (sex-linked). Men only have 1 "x", so if their "x" is mutated, they will have the disease. Women have 2 "x's", so they can have 1 mutated "x" and 1 normal "x", and be a carrier of the disease, with mild or no symptoms. ...Read more

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What are the signs of hemophilia? 

What are the signs of hemophilia? 

Bruises or bleeding: Often bruises or bleeding episodes are signs of hemophilia. Blood test can be done by a physician to evaluate for hemophilia if there are concerning symptoms or signs. ...Read more

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What are the effects of hemophilia?

Bleeding: Hemophiliacs bleed excessively and bleed into their tissues with minor trauma. Hemophilia a patients tend to bleed into their joints. ...Read more

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Is there a cure for hemophilia?

No: Not yet, however, the disorder can be managed with injections of recombinant coagulation factors. ...Read more

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Is there a cure for hemophilia ?

Control is achieved: Not a cure, but control of bleeding episodes is achieved by periodic infusion of purified, genetically engineered, human factor viii, defects of which cause the most common form of hemophilia. ...Read more

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What type of mutation causes hemophilia?

What type of mutation causes hemophilia?

Hemophilia: A mutation on the x chromosome that affects the blood clotting factors viii or ix. ...Read more

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Could hemophilia occur due to a mutation?

Could hemophilia occur due to a mutation?

Yes, a gene mutation: Hemophilia "a" is a hereditary bleeding disorder where there is a deficiency in clotting factor viii (factor viii is needed for blood clotting). It is inherited on the x-chromosome (sex-linked). Men only have 1 "x", so if their "x" is mutated, they will have the disease. Women have 2 "x's", so they can have 1 mutated "x" and 1 normal "x", and be a carrier of the disease, with mild or no symptoms. ...Read more

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Is a normal lifespan possible with hemophilia?

Is a normal lifespan possible with hemophilia?

Probably: You must be under close doctor monitoring, and be sure to follow your regimen for treating any bleeding. In the past, because of contamination of the clotting factors with hepatitis, and HIV most people with hemophilia did not live a normal life span, but now the clotting factor replacement therapies are not contaminated. ...Read more

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Can you tell me how bleeding cause hemophilia?

Can you tell me how bleeding cause hemophilia?

It dosent: The bleeding is not the cause of this condition but the sign of the disorder. The person with hemophilia lacks some of the factors responsible for clotting. Thus any bleeding lasts for a longer time and is more profound as compared to a person with normal clotting mechanisms. ...Read more

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Can you have facial piercings if you have hemophilia?

Can you have facial piercings if you have hemophilia?

Not recommended: Even the association of professional piercers recommends that you should not get a piercing if you have hemophilia. Bleeding is a risk associated w piercing even if you do not have hemophilia. ...Read more

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If I have hemophilia, are bug bites a serious concern?

No: A hemophiliac's platelets work normally and they are quite sufficient to close these, the nicks you may get shaving, paper cuts, small knife cuts and in fact all but rather severe or repetitive injury, even when the hemophilia is severe. ...Read more

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What is the life expectancy of someone with hemophilia? 

Near normal: The disorder can be of varying severity, but robust treatment options are available, including recombinant drugs and gene therapy. If severity is low and resistance to drugs do not develop life expectancy is near normal. ...Read more

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Does inbreeding in families cause hemophilia to develop?

Not usually: Despite emphasis on hemophilia and royal families, rasputin's influence depended on common relatives among english/russian royalty. The well-known hemophilias are x-linked, passed through normal women with 2 xs to men with one. Inbreeding increases chances for matching up of rare, autosomal recessive mutations in spouses (e.g., cystic fibrosis, tay-sach's diseases). ...Read more

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Why's sickle cell anemia relevant to reproductive health?

Why's sickle cell anemia relevant to reproductive health?

Safety + children: Depending on the specifics, a woman with sickle cell may need a "high-risk" OB when she gets pregnant. Also, sickle cell is usually inherited; using in vitro fertilization (with preimplantation genetic diagnosis) we can prevent the children from inheriting the disease. ...Read more