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Doctor insights on: Hemolytic Disease Of Newborn In Children

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What's hemolytic disease of newborn?

What's hemolytic disease of newborn?

Different blood type: Hemolytic disease of newborn is caused by different blood types in mom and baby. Classically, mom is rh negative (a- or o-, etc). The baby is rh positive. Mom then make rh antibodies that cross over to the baby and cause breakdown of the red blood cells. This can make the baby very sick. ...Read more

Dr. Ronald Krauser
1 Doctor shared a insight

Neonatal (Definition)

The term neonatal is generally used to describe events that occur with an infant within the first 30 days after birth. Some practitioners are looser with the definition & extend the ...Read more


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What are the tests for hemolytic disease of newborn?

What are the tests for hemolytic disease of newborn?

Test for mom/baby: The baby will get test like Coombs testing, hemoglobin or cbc, bilirubin tests and reticule yet counts. The Coombs tests shows that an antibody is cause the hemolysis. The antibody specificity can be determined by additional tests. These antibody levels can be measured in mom and baby. Most of these antibodies will cause hemolysis. Some can cause decreased RBC production in the baby. ...Read more

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What are the symptoms associated with hemolytic disease of newborn?

Jaundice and anemia: Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. ...Read more

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What is the definition or description of: Hemolytic disease of newborn?

What is the definition or description of: Hemolytic disease of newborn?

HDN: During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. Hemolytic Disease of the Newborn occurs when the immune system of the mother sees a baby's red blood cells as foreign and produces antibodies against the baby's red blood cells. These antibodies attack the red blood cells in the baby's blood and cause them to break down too early. ...Read more

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What is the treatment for hemolytic disease of newborn?

What is the treatment for hemolytic disease of newborn?

Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read more

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How can hemolytic disease of the newborn occur?

Antibodies: Mom has an antibody against an antigen that baby has on the red cells acquired from dad. The antibody crosses the placenta. Rhogam has done wonders to prevent antibodies against rh/d from causing the devastating illness that used to be common. ...Read more

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Can you tell me the three classifications of hemolytic disease of the newborn?

Can you clarify?: The three most common blood group systems to cause hemolytic disease of the newborn are rh (usually d antigen, sometimes others), ABO (more common but less troublesome) and kell, though others can do it as well. Was this your question? If not, please write back. ...Read more

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Are there any major complications to hemolytic disease of the newborn on the baby?

Yes: Hemolytic disease of the newborn can result in significant jaundice and/or anemia, either of which may require emergency medical intervention. Even when the jaundice subsides, the infant is at risk for anemia for the first several weeks of life. ...Read more

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How often is hemolytic disease of the newborn fatal?

How often is hemolytic disease of the newborn fatal?

Depends on form: Decades ago when I started rh hemolytic disease was often fatal during pregnancy & problamatic in newborns. Surviving infants often needed many exchange transfusions & had worrisome futures. Then a treatment called Rhogam came along & has ended that nightmare. In 26 yrs, I have transfused 1-2 ABO babies primarily for late stage anemia but had no fatalities. Rh disease is a problem without rx. ...Read more

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Please tell me the dangers of hemolytic disease of the newborn (abo)?

Usually mild: Most of these kids have a brief issue with moderate elevations in bilirubin in the first first few days, but may face anemia days and weeks down the road. I remember a single ABO kid needing a transfusion at 6 weeks when this issue arose in 3 decades as a pediatrician. ...Read more

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Can symptoms of hemolytic disease of the newborn happen a week after birth?

Can symptoms of hemolytic disease of the newborn happen a week after birth?

HDN: The process of hemolytic disease of the newborn (HDN) starts soon after birth, however the symptoms (mainly jaundice) may not be detected if clinicians do not maintain a high index of suspicion. HDN due to Rh incompatibility is very rare in the US, but ABO incompatibility should be suspected whenever the mother has type O blood and the baby has either type A or B blood and there jaundice. ...Read more

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How can hemolytic disease be prevented in a newborn?

How can hemolytic disease be prevented in a newborn?

ABO hemolysis: Hemolysis in newborns due to ABO incompatibility is not preventable, but is manageable under the care of an experienced pediatrician or neonatologist. For this reason, newborns from mothers with type O blood type or who are Rh- will be screened closely for this condition, as early recognition and intervention is key to successful recovery. ...Read more

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If my 2nd son had hemolytic disease of the newborn, what are the chances the rest of my babies will as well?

If my 2nd son had hemolytic disease of the newborn, what are the chances the rest of my babies will as well?

Depends: Hemolytic disease of the newborn, which is due to rh or ABO incompatibility, happens when the newborn's blood type is incompatible with the mother's, and the mother has passed antibody to the baby in utero. In ABO disease, the mother must be type o and the baby either a or b. In rh disease, the mother must be rh- and the baby rh+. So, subsequent risk depends on the fetus' blood type. ...Read more

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Is there a genetic test for hemolytic disease of the newborn?

Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more

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Does the possibility of an unborn baby getting antibodies c&d, (hemolytic disease of the newborn) increase with each pregnancy?

Does the possibility of an unborn baby getting antibodies c&d, (hemolytic disease of the newborn) increase with each pregnancy?

HDN: With each pregnancy the mother increases her chances of developing antibodies which can in turn cross the placenta and harm the fetus. ...Read more

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Can a rh+ baby during pregnancy can lead to hemolytic disease?

Can a rh+ baby during pregnancy can lead to hemolytic disease?

Yes. But only...: Mom would need to be rh negative. This would sensitize the mom, producing an anti-rh antibody that can cross the placenta and began to hemolyze the rh positive cells of the infant. This can began to occur early in the pregnancy, making the unborn child very sick. Or it can be detected at birth and cause prolonged jaundice. Subsequent children may be more affected. Mom needs rhogam. ...Read more

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If mother has type o positive blood and newborn has a positive can it cause a crossover causing hemolysis or jaundice?

If mother has type o positive blood and newborn has a positive can it cause a crossover causing hemolysis or jaundice?

A to O set up: You do not need crossover to set up a problem of hemolysis if baby has this type. Mom's system can become sensitized in her lifetime to dietary products that will cause antibody formation to the blood type a, and this is usually only a problem after birth when the hemolysis and bilirubin disposal relies on babies system to keep the jaundice under control. Docs monitor and treat as needed. ...Read more

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Will I get or spread any diseases to my newborn or older children from stepping on someone’s spit in? I put sanitizer on the ground & rubbed on soles

Will I get or spread any diseases to my newborn or older children from stepping on someone’s spit in? I put sanitizer on the ground & rubbed on soles

You should be fine!: Most infections are spread by hand to mouth contact or by aerosol when someone sneezes into the air. You have gone a step further by using sanitizer. Just remember to wash hands before cooking or eating handling your infant. ...Read more

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How can group b strep disease affect a newborn?

Group b infection: Newborn can get group b strep infection either during passage through birth canal or after birth coming in contact with an adult carrier of this bacteria
the infection quickly spreads into the blood stream and can make the newborn really sick and has to be treated with IV antibiotics. ...Read more

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Is it safe for me to give my frozen expressed breastmilk to a newborn of a friend who can't produce? I'm healthy with no disease or bad habits.

Is it safe for me to give my frozen expressed breastmilk to a newborn of a friend who can't produce? I'm healthy with no disease or bad habits.

Possibly: There are quite a number of safety measures that human milk banks go through to make sure their donors are healthy enough to donate frozen expressed breast milk. I would advise you to contact your local children's hospital or a human milk bank and find out what screening they do before you attempt to donate milk. The handling of the milk is also crucial in preventing spoilage. Be safe first! ...Read more

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How can huntington's disease affect a newborn?

How can huntington's disease affect a newborn?

Genetic disease: Huntington's disease is inherited in autosomal dominant pattern. Even though it is a genetic defect, initial symptoms almost never present themselves in new born period. Earliest presentation of symptoms is at 20-30 yrs of age. Tremors, loss of co-ordination, seizures, dementia are clinical symptoms. It's a progressive disease which is usually fatal within 10-30 yrs of initial presenting symptoms. ...Read more

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What are the most common nervous system diseases seen in newborns?

Most common: Intraventricular hemorrhage for preterm babies, hypoxic ischemic encephalopathy, stroke, dandy walker and arnold chiari malformations ...Read more

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What diseases is the umbilical cord of a newborn baby used to treat?

What diseases is the umbilical cord of a newborn baby used to treat?

Blood cell disorders: It is the blood obtained from the cord, not the cord itself, that is being used to treat disease. Early, primitive cells, called stem cells, are used to treat many disorders of the blood, including aplastic and other anemias, leukemias, certain immunologic diseases, and even some metabolic disorders. Ongoing research includes non-blood diseases, such as stroke, diabetes, and even heart attacks. ...Read more

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How soon can sickle cell disease be tested for after the newborn is born?

How soon can sickle cell disease be tested for after the newborn is born?

Sickle cell testing: In the United States, all states mandate testing for sickle cell anemia as part of their newborn screening programs. The test uses blood from the same blood samples used for other routine newborn screening tests. The test can show whether a newborn infant has sickle hemoglobin (from http://www. Nhlbi. Nih. Gov/health/health-topics/topics/sca/diagnosis. Html). ...Read more

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Is there any alternative to surgery for spinal bifida? I have heard this disease is mostly found/prone to newborn child?

Is there any alternative to surgery for spinal bifida? I have heard this disease is mostly found/prone to newborn child?

See below: The surgery for this type of condition is usually done to make sure there is no exposed spinal tissue. The long term effects may also need surgery. Talk to your neurosurgeon about options and treatment plans. ...Read more

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Can someone get a disease from a needle stick that caused them to bleed from a needle that was used while giving iron shots to newborn baby pigs?

Can someone get a disease from a needle stick that caused them to bleed from a needle that was used while giving iron shots to newborn baby pigs?

Unlikely: But doubt that this has ever been the subject of a detailed scientific investigation. If you develop any suspicious symptoms would take this history with you to the doctor and be evaluated. Good luck. ...Read more

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What are some lung diseases in newborns and what causes them?

What are some lung diseases in newborns and what causes them?

A few: One of the most common lung difficulties we see, especially with c-section babies, is transient tachypnea of the newborn. This occurs when there is still fluid in the lungs, because the baby didn't exit via the birth canal and literally have the fluid squeezed out. Infections can also occur resulting in pneumonia. Some babies "transition" slowly, & need a little help learning to breath room air. ...Read more

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What's a way to explain to my job that I have an inherited hemolytic anemia disease?

What's a way to explain to my job that I have an inherited hemolytic anemia disease?

? necessary: Is it any of their business? If trying to explain it, suggest it is a breakup of blood cells in the blood stream. ...Read more

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How long does a neonatal auto-immune disease last for?

How long does a neonatal auto-immune disease last for?

Depends: There are many different types of "neonatal autoimmune diseases" each with theire own time frames. Usually when someone is discussing neonatal autoimmune diseases they are talking about maternal antibodies that have passed through the placenta and are directed against antigens in the fetus and/or newborn child. ...Read more

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What can elevated liver enzymes mean in a newborn besides liver disease?

What can elevated liver enzymes mean in a newborn besides liver disease?

Elevated liverenzyme: For liver enzymes to get elevated you need to have inflamation in the liver, so anything that does that can increase the liver enzymes including infections, congenital abnormalities. You should talk to the newborn's pediatrician for a clearer answer, as he/she will know ur newborn better.. ...Read more

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How long before sickle cell disease can be tested for after the newborn screen?

How long before sickle cell disease can be tested for after the newborn screen?

Soon!: All states and the district of columbia screen for sickle cell disease as part of the newborn screen. The testing is very accurate and really doesn't need to be repeated if it is normal. If it is abnormal and confirmatory testing is desired it can an should be done promptly so appropriate treatment can be started as soon as possible. ...Read more

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Could newborns be around people with sickle cell disease or after they get treatment done?

Confusing question: Newborns need to stay away from those known to have active contagious disease. Sickle cell is not contagious, and a healthy sickle cell patient need not be avoided any more than any other person. ...Read more