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Doctor insights on: Hemolytic Disease Of Newborn

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Dr. Robin Ohls
17 doctors shared insights

Hemolytic Disease Of Newborn (Overview)

During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. Hemolytic Disease of the Newborn occurs when the immune system of the mother sees a baby's red blood cells as foreign and produces antibodies against the baby's red blood cells. These antibodies attack the red blood cells in the baby's blood and cause them to break down too early.


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What are the symptoms associated with hemolytic disease of newborn?

What are the symptoms associated with hemolytic disease of newborn?

Jaundice and anemia: Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. ...Read more

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Dr. Robin Ohls
17 doctors shared insights

Hemolytic Disease Of Newborn (Overview)

During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. Hemolytic Disease of the Newborn occurs when the immune system of the mother sees a baby's red blood cells as foreign and produces antibodies against the baby's red blood cells. These antibodies attack the red blood cells in the baby's blood and cause them to break down too early.


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Is there a genetic test for hemolytic disease of the newborn?

Is there a genetic test for hemolytic disease of the newborn?

Yes: Hemolytic disease of the newborn, causing yellow skin and eyes (jaundice) with anemia, is most commonly due to a "set-up"--a blood type difference between mother and child. Blood types are caused by genes at the ABO and other loci (rhesus being most damaging), with o type or rh negative moms making antibodies to red blood cells of a or b or rh+ fetuses (if mom is o and fetus ab, baby switched), . ...Read more

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What are the tests for hemolytic disease of newborn?

Test for mom/baby: The baby will get test like coombs testing, hemoglobin or cbc, bilirubin tests and reticule yet counts. The coombs tests shows that an antibody is cause the hemolysis. The antibody specificity can be determined by additional tests. These antibody levels can be measured in mom and baby. Most of these antibodies will cause hemolysis. Some can cause decreased RBC production in the baby. ...Read more

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What is the treatment for hemolytic disease of newborn?

What is the treatment for hemolytic disease of newborn?

Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read more

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Whats hemolytic disease of newborn?

Different blood type: Hemolytic disease of newborn is caused by different blood types in mom and baby. Classically, mom is rh negative (a- or o-, etc). The baby is rh positive. Mom then make rh antibodies that cross over to the baby and cause breakdown of the red blood cells. This can make the baby very sick. ...Read more

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What are the tests for hemolytic disease of newborn?

Test for mom/baby: The baby will get test like coombs testing, hemoglobin or cbc, bilirubin tests and reticule yet counts. The coombs tests shows that an antibody is cause the hemolysis. The antibody specificity can be determined by additional tests. These antibody levels can be measured in mom and baby. Most of these antibodies will cause hemolysis. Some can cause decreased RBC production in the baby. ...Read more

See 1 more doctor answer
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What are the symptoms associated with hemolytic disease of newborn?

Jaundice and anemia: Hemolytic disease of the newborn (hdn) may develop when a mother and her unborn baby have different blood types. The mother produces substances called antibodies that attack the developing baby's red blood cells. The most common form of hdn is ABO incompatibility, which is usually not very severe. The least common form is rh incompatibility, which can be very severe, but can be prevented. ...Read more

See 1 more doctor answer
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What is the definition or description of: Hemolytic disease of newborn?

HDN: During pregnancy, red blood cells from the unborn baby can cross into the mother's blood through the placenta. Hemolytic Disease of the Newborn occurs when the immune system of the mother sees a baby's red blood cells as foreign and produces antibodies against the baby's red blood cells. These antibodies attack the red blood cells in the baby's blood and cause them to break down too early. ...Read more

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What is the treatment for hemolytic disease of newborn?

Various: Hemolytc disease can be mild and treated with bili lights. In extreme cases, it may be picked up early in pregnancy from an antibody screen. If positive, the antibody is identified. If a concerning antibodies present, the blood counts of the baby will be followed closely. Intrauterine transfusions may be required in these rare instances. ...Read more

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Dr. Olav Jaren
1 doctor shared a insight

Neonatal (Definition)

The term neonatal is generally used to describe events that occur with an infant within the first 30 days after birth.Some practitioners are looser with the definition & extend the ...Read more