Doctor insights on:
Hemolytic Anemia Due To G6pd Deficiency
Can zinadol(cefuroxime) induce hemolytic anemia to g6pd patients?
There is a risk of hemolysis with cephalosporins, is it greater for g6pd patients?
Not likely a risk: The list of antibiotics to avoid in patients with G6PD deficiency include nitrofurans, sulfonamides and quinones (and chloramphenicol). Some of these are considered to be safe at usual doses for class II and III disease. Cephalosporins should not contribute to hemolysis. ...Read moreSee 1 more doctor answer
Cell membrane damage: Pyruvate a kinase deficiency results in reduced ability of red cells to make atp -the "energy source" of cells. Atp is also necessary to protect cells from damaging compounds such as free radicals. With decreased energy supply the cell is not able to maintain appropriate concentrations of electrolytes and fluids, becomes distorted or stiff, and then is destroyed in the spleen or liver. ...Read more
I had a peptic ulcer and now i have anemia what should i do and eat to increase red blood cells and i also have G6PD deficiency ?
Test for H pylori, +: H pylori bacteria are a common cause of peptic ulcers.A 2-week treatment can get rid of it, and eliminate recurrence. Gastric bleeds will give heme positive stools. But the anemia may be from hemolysis caused by exposure to something which causes acute hemolysis (busting open of your fragile red cell membranes) in G6PD deficiency. Serum free hemoglobin will be high. Learn what you must avoid! ...Read more
RBC breakdown: Hemolytic anemia is where red blood cells are destroyed too quickly. There are many possibilities that would cause this rbc breakdown. Antibodies, abnormal rbc membranes (spherocytosis), abnormal hemoglobins (sickle cell, thalassemia), abnormal rbc enzymes. If hemolytic anemia is is suspected, many tests may be ordered to determine the cause. ...Read moreSee 1 more doctor answer
Cause of hemolysis: Once hemolysis is thought to be occurring, the cause is saught. The causes are many. Some are inherent to the red blood cell (sickle cell, spherocytosis, thalassemia, g6pd deficiency). Some are from antibodies. Some are from other causes of destruction within the blood vessels (mechanical heart valves, hemolytic uremic syndrome). This work up is quite involved. ...Read moreSee 1 more doctor answer
Autoimmune reaction: Cephalosporins interact with red blood cell membranes. The body can sometimes produce antibodies against cephalosporins that also interact with the surface of red blood cells. These antibodies thus activate the body's immune system to attack its own red blood cells, causing hemolytic anemia. This is a rare but severe side effect of cephalosporins. ...Read more
Possibly: Hemolytic anemia may have numerous causes including toxins, infections, genetic diseases, autoimmune diseases, drugs, certain types of food, etc. So theoretically if you know what the cause is then it can be avoided. Therefore an adequate diagnostic workup by your doctor is necessary. ...Read moreSee 1 more doctor answer
Stopping dapsone: The best way to treat Dapsone related anemia is by discontinuing dapsone. Dapsone causes hemolytic anemia which is dose-dependent and can be stopped only with discontinuing the drug. Usual practice is to use the lowest possible doses of Dapsone and support with vitamin E and folic acid. ...Read moreSee 1 more doctor answer