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Doctor insights on: Hemoglobinuria

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What causes hemoglobin E-beta thalassemia?

What causes hemoglobin E-beta thalassemia?

Thalassemia : This is a genetic hemolytic blood disorders transmitted to you from your parents in your genes & instead of having the normal Hgb A, it becomes abnormal Hgb. there are different types of thalassemia. If both parents are carriers or have the disease then the offspring might get the disease. I hope this helps. Good luck. ...Read more

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How can I cure paroxysmal nocturnal hemoglobinuria?

How can I cure paroxysmal nocturnal hemoglobinuria?

You can't: Anyone telling you otherwise is scamming you. It's an acquired genetic mutation. Hopefully you can manage it -- it is a difficult and dangerous disease. Learn all you can about it as you'll have choices to make. Best wishes. ...Read more

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Is sickle cell anemia hereditary?

Is sickle cell anemia hereditary?

Yes.: it is an autosomal recessive disorder, meaning that both parents must be carriers of the mutation. If they are, the chance of each child being affected is 1 in 4. ...Read more

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Low hemoglobine, hematocrit&creatinine w/anisocytosis poikilocytosis anisochromia microcytes dianocytes schitocytes difusse basophilia, what it means?

Low hemoglobine, hematocrit&creatinine w/anisocytosis poikilocytosis anisochromia microcytes dianocytes schitocytes difusse basophilia, what it means?

Get it looked at: Your peripheral smear and your labs need to be reviewed by a hematologist or hematopathologist for accuracy of the lab report and possible diagnosis. It may be nothing more than minor genetic fluke, or something significant. Heads up -- vasculitis in the gall bladder wall is usually nothing to worry about though it scares some pathologists into overcalls. ...Read more

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Difference of myoglobinuria from hemoglobinuria?

Difference of myoglobinuria from hemoglobinuria?

Differences: Myoglobinuira (m) is the result of the muscle break down, due to trauma, where myglobin in the muscle is found in the urine. Hemoglobinuria is a condition in which hemoglobin is found in abnormally high concentrations in the urine. The condition is often associated with hemolytic anemia. Excess hemoglobin is filtered by the kidneys, which excrete it into the urine. ...Read more

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How can I treat paroxysmal nocturnal hemoglobinuria fast?

No easy fix: Anyone telling you otherwise is deceiving you. This is a lifelong health problem though the severity between cases is widely variable. Your physician will guide you if you need transfusion, anticoagulation and/or eculizumab. ...Read more

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Is myoglobinuria dangerous?

Is myoglobinuria dangerous?

Yes: Myoglobinuria implies injury to the muscles and that can be dangerous depending on the muscles injured, the extent and severity of injury. ...Read more

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What is hemoglobin E-beta thalassemia?

What is hemoglobin E-beta thalassemia?

Sever anemia: This syndrome is quite common in Thailand ,where there. is a high incidence of the genes for B0 thalassemia and Be golobin ...Read more

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
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Does nomochromic normocytic anemia indicate renal impairment?

Dr. Liawaty Ho Dr. Ho
1 doctor agreed:
Does nomochromic normocytic anemia indicate renal impairment?

Not necessarily: Normocytic normochromic anemia can be caused by acute blood loss, early iron deficiency, bone marrow supression, anemia of chronic disease, anemia of renal insufficiency, anemia caused by endocrine problem etc. ...Read more

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Ferritin13, Iron167, TIBC496, Transferrin392, %Sat.34, Hemoglobin13.9 Is this anemia or iron overload?

Neither: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Having said that, the data you provided suggests that your iron stores at the low end, but you are not anemic.
For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form.
Practice safe sex, if you have sex. ...Read more

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Is autoimmune hemolytic anemia hereditary?

Is autoimmune hemolytic anemia hereditary?

No: It can be due to an underlying autoimmune disorder, such as lupus or rheumatoid arthritis. In this case, the underlying autoimmune disorder may be hereditary; but the autoimmune hemolytic anemia is not hereditary. It is simply the manifestation of the underlying disorder. There are also several causes of autoimmune hemolytic anemia that are not inherited. ...Read more

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Paroxymal nocturnal hemaglobinuia means what?

Paroxymal nocturnal hemaglobinuia means what?

It is a disease ...: It is rare type of blood disorder where the red blood cells(rbc) are not healthy and are prone to intermittent hemolysis(breakdown of rbcs). It often shows up as dark(brown) colored urine especailly when you wake after nights sleep ...Read more

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Urine pH 5.0,alk phos 62,whit blood count 6.0 red blood 4.62 hemoglobin 14.4 hematocrit 42.8 mean corpuscular hemoglobin 31.2 creatinine 0.62 meaning?

Urine pH 5.0,alk phos 62,whit blood count 6.0 red blood 4.62 hemoglobin 14.4 hematocrit 42.8 mean corpuscular hemoglobin 31.2 creatinine 0.62 meaning?

OK ...: The isolated numbers are ok, but one should interpret these through comparing prior serial values if available and correlating with current clinical pictures so to deduce their clinical significance. Why? It's because every thing always displays itself at a certain spot of its own full spectrum; likewise, any lab test does. ...Read more

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Low rbc, high urea nitrogenBUN, high urine osmolality,high urine creatinine random,high UA sodium random,ab. urine epithelial cell,k etones,ur.mucus ?

Low rbc, high urea nitrogenBUN, high urine osmolality,high urine creatinine random,high UA sodium random,ab. urine epithelial cell,k etones,ur.mucus ?

Dehydrated: 39 F from Indy of unknown ethnicity medical or drugs notes low rbc high bun and high urine Na creat. ANS: sounds like anemia and dehydration or renal disease. The latter is often due to eating too much salt and HTN and choosing the wrong grandparents. Your Dr knows you best so ask them. ...Read more

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How do I get rid of hyper pigmintattion?

How do I get rid of hyper pigmintattion?

Hydroquinone: Hyperpigmentation if often caused be inflammation du to injury or infection and the action of the sun. Hydroquinone, and sunscreens can revers the process and improve the hyperpigmentation. ...Read more

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What is sickle cell beta thalassemia?

What is sickle cell beta thalassemia?

Got both mutations: A person has sickle cell beta thalassemia if he inherited one gene mutation for sickle cell anemia, and also inherited one gene mutation for beta thalassemia. He can have symptoms of sickle cell disease, unlike patients with only sickle cell trait who are generally without symptoms. ...Read more

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Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

Ferritinin 800, iron 167. And macrocytic anemia. Liver , kidney, wbc, platelets, neutrophil, B12 normal. Why? Is it preleukemia?

At least 2 problems: You realize that we can't diagnose you. With the very high serum ferritin and up-there serum iron, assuming the blood was not drawn during an acute illness, you have hemochromatosis until proved otherwise. How anemic you are, whether this is real macrocytosis, what your physical findings and other labs are are best known to your hematology consultation. Hope nobody gave you iron supplements. ...Read more

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Does alpha thalassemia causes leukemia?

Does alpha thalassemia causes leukemia?

No: Alpha and beta thalassemia have not been reported to cause leukemia, which is cancer of the white blood cells. There is a study of beta thal. Major & intermedia patients in iran, where researchers found 5 leukemia cases in about 4, 600 patients. That is a higher rate of leukemia than in the general population there, but details were unavailable as to what other factors were present in the patients. ...Read more

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Causes for high wbc, rbc, hemoglobin, hematocrit, and neutrophils?

Causes for high wbc, rbc, hemoglobin, hematocrit, and neutrophils?

Various: Causes of high counts can be due to a variety of reasons, some include infections, environmental factors, bone marrow disorders and cancer. You should see your local hematologist to determine cause and management. ...Read more

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Is sickle cell anemia a severe condition?

Is sickle cell anemia a severe condition?

Depends: It depends on the type of sickle cell disease a patient has, and how many attacks they get in a year and how severe those attacks are. ...Read more

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Why does malaria cause hemoglobinuria?

Why does malaria cause hemoglobinuria?

Hemoglobinuria: "Haemoglobinuria is one of the manifestations of severe malaria and results from severe intravascular haemolysis. Glucose-6-phosphate dehydrogenase (G6PD) deficiency has been implicated in its aetiology. Haemoglobinuria may be associated with severe anaemia and, less frequently, acute renal failure." See: http://www.malariajournal.com/content/11/1/336 ...Read more

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Difference of myoglobinuria from hemoglobinuria?

Differences: Myoglobinuira (m) is the result of the muscle break down, due to trauma, where myglobin in the muscle is found in the urine. Hemoglobinuria is a condition in which hemoglobin is found in abnormally high concentrations in the urine. The condition is often associated with hemolytic anemia. Excess hemoglobin is filtered by the kidneys, which excrete it into the urine. ...Read more

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How can I cure paroxysmal nocturnal hemoglobinuria?

You can't: Anyone telling you otherwise is scamming you. It's an acquired genetic mutation. Hopefully you can manage it -- it is a difficult and dangerous disease. Learn all you can about it as you'll have choices to make. Best wishes. ...Read more

See 1 more doctor answer
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How to diagnose Paroxysmal nocturnal hemoglobinuria??

Blood test and hx: Most important is the history of blood in the morning on urination for no apparent reason. Other causes of blood in urine must be ruled out. Sometimes blood may be so small or dilute that urine is not red but may just appear dark. A family history or relative with PNH is also helpful but not necessary. Finally a blood test that will test for PNH must be abnormal. Is there a concern for PNH? ...Read more

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How can I treat paroxysmal nocturnal hemoglobinuria fast?

No easy fix: Anyone telling you otherwise is deceiving you. This is a lifelong health problem though the severity between cases is widely variable. Your physician will guide you if you need transfusion, anticoagulation and/or eculizumab. ...Read more

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Paroxysmal nocturnal hemoglobinuria: are there many symptoms?

Not always: You may not even have abnormally-colored urine in the mornings. Or you may develop anemia or have deep vein thrombi and their complications. If you have pnh, this is a management problem for you with your hematologist, and you'll do best to learn as much as you can about it. ...Read more

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Do you know if there are any experts who have treated more than 1 patient with paroxymal cold hemoglobinuria? I

PCH~: A: millions. Just Google (or look up in the Medical Section of your local phone directory) any "hematologist" or in the USA (Heme-Onc) doc, of any worth and reknown and go see him. This is not esoterica, my dear ! ...Read more

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People with thalassemia or hemolytic anemia, why they present usually with hemoglobinuria ? Inspite they have reduced rbcs !

Hemoglobinuria....: Is simply the presence of hemoglobin in the urine, and can be seen in any condition that results in intravascular hemolysis. It is not a specific finding. Indeed it can be seen in thalassemias, where red cells are more prone to oxidant stress and mechanical disruption. There many intrinsic and extrinsic reasons for hemolysis to occur. Hope this helps. ...Read more

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I was just wondering why does malaria cause haemoglobinuria?

I was just wondering why does malaria cause haemoglobinuria?

Malaria: The malaria parasite infects red blood cells (rbc's) where it goes through several multiplication stages. The rbc eventually ruptures, releasing the parasites and haemoglobin. The haemoglobin is filtered by the kidney and is excreted into the urine. Each new parasite then goes on to infect another rbc and the cycle is repeated. ...Read more

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Who am i?

A little more: Your question will need to have a little more context in order to receive a meaningful answer. If it was meant to check if questions are answered here you have your answer. ...Read more

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Am I dying?

Am I dying?

We all are: A 3-word question with no details... well, life is short on Earth, regardless of whether a person lives 3 days, 3000 days, or 30,000 days. It is not length of one's life that matters, but the quality of the life lived. The goal is not to live a long life, but to live a good life. Even if a person makes it all the way to age 82, that's only 30,000 days. ...Read more

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I have cold?

I have cold?

Symptoms?: The most common symptoms of a cold are sneezing, running nose, congestion and scratchy throat. Additional symptoms can be coughing, headaches, mucus dripping down the back of the throat, loss of appetite and fever (in children). ...Read more

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I have cold?

I have cold?

Cold: Tips: sore throat – gargle with warm salt water (1/2 tsp salt in 8 oz of water). Get strep test/culture if very sore. Congestion – saline nose drops or netti pot. For anti-inflammatory effect & mobilizing mucus- homemade chicken noodle soup. Hydrate- lots of water/clear broth/ add honey & a small amt. Of lemon juice to chamomile tea.. Fever/ pain – Acetaminophen / nsaid’s rest! ...Read more

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What is asp?

What is asp?

In acupuncture an: Asp is an acupuncture semi-permanent needle. They are made in germany & come in stainless steel, gold, silver & titanium. They are used for auricular (ear) acupuncture. They are usually referred to as "asp's". ...Read more

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Pls help me?

Help: In order to assist you - you need to provide us with more information. Please re-ask and clarify the question that you need help with. Take care. ...Read more

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