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Doctor insights on: Hemoglobin's A Disease

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How is hemoglobin s taken care of in a child?

How is hemoglobin s taken care of in a child?

See below: If they only have one copy of HGB s, then they only have sickle cell trait, which does not need any treatment. If they have two copies, then they have sickle cell. This can result in recurrent pain crisis'. The child will need to have pneumococcal vaccines, which is recommended for all children now, and prophylactic antibiotics. And care by a hematologist. ...Read more

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What is the difference between hemoglobin s and hemoglobin a?

What is the difference between hemoglobin s and hemoglobin a?

Normal and Abnormal: Hemoglobin consists of two pairs of polypeptides chains. It exists inside the red blood cells ANS is important for oxygen transport. Hemoglobin a is one of the normal hemoglobins and has alpha2/beta2 chains. Hemoglobin s is a mutant hemoglobin responsible for sickle cell trait and disease. Hemoglobin s is poorly soluble when deoxygenated given the red cell the sickle shape. ...Read more

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Was tested for sickle cell and the trait. I do not have either one. But I have high hemoglobin s & low a. What other than sickle cell can cause this?

Was tested for sickle cell and the trait. I do not have either one. But I have high hemoglobin s & low a. What other than sickle cell can cause this?

Sickle beta thal: If you have high HGB s and low HGB a, then you have sickle beta-plus thalassemia ( if you have HGB a1), or sickle beta-zero thalassemia. ( if you have HGB a2 not HGB a1). These are both forms of sickle cell disease not trait. Beta zero is just as severe as homozygous sickle cell anemia (hgb ss); beta plus is milder in terms of symptoms. ...Read more

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Hello, i want to know if there is a defferances in the level of hemoglobin s in the people who has sickle cell trait ,,, ?

Hello, i want to know if there is a defferances in the level of hemoglobin s in the people who has sickle cell trait ,,, ?

Yes: There are variations in the expression of Hb S gene and the depending on additional factors the percentage of Hb S in a person with the trait may vary from about 20-70%. The additional factor generally is beta thalassemia trait in the cis or trans position to the Hb S gene. ...Read more

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Toddlers hemoglobin is 10.9, should I be worried? Could it be low because she currently has 5ths disease? Could it be low due to something more seriou

Toddlers hemoglobin is 10.9, should I be worried? Could it be low because she currently has 5ths disease? Could it be low due to something more seriou

Anemia: This is a borderline anemic value, not to worry too much. If recently ill it is possible to be low due to illness, however a toddler's diet typically predisposes them to iron deficiency anemia. If the rest of the blood counts are normal (platelets and WBC) then no reason to worry about something serious. Don't worry, may need some iron supplementation. ...Read more

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What diseases cause the hemoglobin count to decrease?

What diseases cause the hemoglobin count to decrease?

Long answer: Common causes of anemia are iron and folate deficiency. In women, loss of blood through menstruation is a common cause. There is a long list of other causes. See this site for more info. http://www.mayoclinic.org/diseases-conditions/anemia/basics/causes/CON-20026209 ...Read more

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What is hemoglobin e disease?

What is hemoglobin e disease?

Beta thal variant: This is a mild genetic illness that affects the ability of red blood cells to make hemoglobin. The allele responsible has its origin in southeast asia. A one-dose carrier has no problems; a two-dose carrier may be mildly anemic. ...Read more

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Could sickle-hemoglobin c disease be transmitted through blood?

Could sickle-hemoglobin c disease be transmitted through blood?

No: This is a genetic disease. A donor unit with sickle-c will not be accepted, and even if you were transfused with such a unit, it would not affect you. If you perhaps had a hemoglobin electrophoresis after a transfusion, and it showed some sickle and some c hemoglobin, you may have been transfused from two donors each bearing the trait. ...Read more