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Doctor insights on: Hemoglobin D Trait

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Could you tell me the symptoms of hemoglobin d, and any other useful information?

Could you tell me the symptoms of hemoglobin d, and any other useful information?

Usually none: Patients with hemoglobin d disease (both copies of the beta-hemoglobin gene carry the mutation) usually have mild anemia and no symptoms. If someone has both hemoglobin d and the mutation for sickle cell disease, they can have health problems. For an excellent overview of hemoglobin d, see: http://www.Stjude.Org/stjude/v/index.Jsp?Vgnextoid=30f0db6324d6f110vgnvcm1000001e0215acrcrd. ...Read more

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It happens that a man with hemoglobin e-trait father a thalassemic child?

It's possible. : Thalassemia is a condition characterized by reduced expression of either Alpha or beta globins, which together make up hemoglobin. There are people who have Alpha deficiencies that are clinically silent (so called silent carrier). Having a child with person with alpha-thal trait, for example, is one way to have a clinically significant alpha-thal. There are other possibilities as well. ...Read more

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I am a thalassemia trait patient with 10.6 % hemoglobin and I am also normocytic hypochromic anaemia . Can i go to gym and do workout ?

I am a thalassemia trait patient with 10.6 % hemoglobin and I am also normocytic   hypochromic anaemia . Can i go to gym and do workout ?

By all means!: I trust your personal physician is keeping an eye on your thal and will let you know if you develop additional anemia from some other cause. Absolutely -- getting into great physical shape is one of the finest gifts you can give yourself. Think about joining a group that does aerobic fitness together as well. ...Read more

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Was tested for sickle cell and the trait. I do not have either one. But I have high hemoglobin s & low a. What other than sickle cell can cause this?

Was tested for sickle cell and the trait. I do not have either one. But I have high hemoglobin s & low a. What other than sickle cell can cause this?

Sickle beta thal: If you have high HGB s and low HGB a, then you have sickle beta-plus thalassemia ( if you have HGB a1), or sickle beta-zero thalassemia. ( if you have HGB a2 not HGB a1). These are both forms of sickle cell disease not trait. Beta zero is just as severe as homozygous sickle cell anemia (hgb ss); beta plus is milder in terms of symptoms. ...Read more

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My daughter is 2 & her doc said her hemoglobin level was a little low. 10.Something. Doc doesn't think it was anemia but a trait. What does that mean?

My daughter is 2 & her doc said her hemoglobin level was a little low. 10.Something. Doc doesn't think it was anemia but a trait. What does that mean?

Anemia: Do you or does her father have an inherited red blood cell disorder like sickle cell anemia or thalassemia etc? Definitely you should ask your pediatrician further about what he/she means. What trait means most likely that she has a distinguishing genetically determined feature on her complete blood count result- that indicates mild abnormality on the rbc indices but not very significant. ...Read more

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Help docs, is hemoglobin AC a sickle cell trait?

Help docs, is hemoglobin AC a sickle cell trait?

No: Hgb AC is a heterozygous genetic state that is not sickle cell trait ( Hgb AS). Patient's with Hgb AC are clinically well with at worst mild asymptomatic anemia (most are not anemic). Individuals with Hgb AC can have children with Hgb SC (a type of severe sickle cell hemoglobinopathy) if their partner has either sickle cell trait (25% chance) or sickle cell disease (50% chance) ...Read more

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Hello, i want to know if there is a defferances in the level of hemoglobin s in the people who has sickle cell trait ,,, ?

Yes: There are variations in the expression of Hb S gene and the depending on additional factors the percentage of Hb S in a person with the trait may vary from about 20-70%. The additional factor generally is beta thalassemia trait in the cis or trans position to the Hb S gene. ...Read more

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My partner is consistent with haemoglobin e-trait. I have normal hb chromatographic pattern. Is there any chance of thalassaemia of our new born baby?

My partner is consistent with haemoglobin  e-trait. I have normal hb chromatographic pattern. Is there any chance of thalassaemia of our new born baby?

No: Neither of you has thalassemia and there is no chance for your baby to get thalassemia, with the exception of a very very rate de novo mutation. ...Read more