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Doctor insights on: Hemochromatosis Digestive Health

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There's an hemochromatosis health issue in my family. My grandfather had it, but not my father. What are the chances that I have the disease?

There's an hemochromatosis health issue in my family. My grandfather had it, but not my father. What are the chances that I have the disease?

Low, probably: If your granddad had hereditary hemochromatosis caused by homozygous mutations of the hfe gene, then your father has at least one mutation. Your mom may be a carrier - this is pretty common: about 1/9 people with a northern european background have 1 mutation. So your risk of inheriting 2 mutations may be about 3%. However, 75-90% of individuals with 2 mutations never get sick. ...Read more

Dr. (Liz)Phuong Tran
313 doctors shared insights

Hemochromatosis (Definition)

Hemochromatosis is a medical condition caused by iron accumulation in the body. It can be the result of underlying hereditary disease or be due ...Read more


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 is there a special diet I should eat or foods I should avoid for hemochromatosis?

 is there a special diet I should eat or foods I should avoid for hemochromatosis?

Certainly: Red meats are known for iron content in them, so avoid those, avoid foods high in vitamin c, as it increases iron absorption. Foods high in sugar should be avoided, as it increases iron absorption. Avoid raw shellfish.Alcohol in moderation, better off - none. Should eat - nuts, veggies, grains, rice, beans. Coffee and tea are fine if not consumed in excessive amounts. ...Read more

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Could i go into the army with hemochromatosis?

Could i go into the army with hemochromatosis?

No: AR 40-501 Ch 2-e(5) "current or history of metabolic liver disease, including but not limited to hemochromatosis..." No chance of a waiver for that one. ...Read more

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What are the symptoms of hemochromatosis?

Varies: Many times, it is only presented with high iron saturation and or iron storage without having any symptoms. However, the clinical manifestations of iron accumulation can include liver disease, elevation of liver enzymes, skin pigmentation, diabetes mellitus, arthropathy, impotence in males, and cardiac enlargement with or without heart failure or conduction defects etc. ...Read more

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Do a lot of people get hemochromatosis?

It's relatively rare: Hemochromatosis is a disorder where a person has too much iron in the blood. This can cause significant problems as iron will deposit in areas like the hear and liver. While it is typically rare, it can be seen if someone takes too much iron supplement. Generally, men should not take iron if they are otherwise healthy. Women, on the other hand, are usually ok provided they are still mentruati. ...Read more

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I want to know what's the impact of hemochromatosis?

Get treated or die: It's as simple as that. Common hereditary hemochromatosis is by far the easiest to manage of all the common, deadly diseases of young people. It announces itself as elevated liver enzymes, impotence, an odd skin color, sore joints at the base of the thumbs, glucose intolerance, or whatever. Accept therapeutic phlebotomy and you'll feel much better. If it's missed or neglected, it's deadly. Period. ...Read more

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No one in my family has ever been diagnosed with hemochromatosis or had any of the symptoms; how could I possibly have this disease?

No one in my family has ever been diagnosed with hemochromatosis or had any of the symptoms; how could I possibly have this disease?

Recessive genetics: Hereditary hemochromatosis is a recessive genetic disease - you have to inherit two mutations, one in each of your two hfe genes, to develop this condition. Your parents would be carriers but completely unaffected. What's more, only 10-15% of folks with two mutations ever get sick. The american hemochromatosis society (http://www.Americanhs.Org/) has more information. ...Read more

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What are some of the symptoms of hemochromatosis?

What are some of the symptoms of hemochromatosis?

A few: Lack of energy, abdominal pain, memory fog, loss of sex drive, heart flutters, irregular heart beat. When symptoms are associated with hemochromatosis, these usually begin in men in their late 20’s to early 30’s. In women, symptoms usually start about 10-15 years after they stop having a period due to menopause, birth control pills or hysterectomy. ...Read more

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Why do people develop hemochromatosis?

Why do people develop hemochromatosis?

It's in the genes: In hereditary (= inherited from parents) hemochromatosis, too much iron is absorbed by the gut & deposits in tissues. Liver, heart, other damage can result. It is autosomal recessive: both parents must carry the gene & not all offspring will be affected. Secondary (= due to other causes) hemochromatosis can occur with certain types of hemolytic anemia (red blood cells bursting, releasing iron). ...Read more

Dr. Ali Yazdy
370 doctors shared insights

Digestive Health (Definition)

Digestive health refers to the proper functioning of the digestive tract, including the stomach, ...Read more