Doctor insights on:
Hemochromatosis And Polycythemia
How is polycythemia rubra vera differentiated from polycythemia associated with stress? RBC only elevated once in life. HGB/HCT elevated often.
Stress?: Stress doesn't cause polycythemia. Being dehydrated is a common cause. If your Hgb/Hct is only slightly elevated, stop worrying -- reference ranges are set so that several percent of healthy folks fall outside. If it's well above, consider a workup for the causes, including a variant hemoglobin and a subtle right-to-left shunt. ...Read more
Is milk thistle dangerous for people with neutropenia, thrombocytopenia and anemia but with iron overload?
Straightforward: Sickle cell trait is not a disease, it is a genetic mutation. In most cases it has no health problems associated with it. The only thing to be "done" for it is to ensure the person with it understands the significance that having it might have on their children. Iron deficiency responds to iron therapy; depending on the pt's age and situation tests may be needed to determine why it developed. ...Read moreSee 1 more doctor answer
No one thing!: They are unrelated. Polycythemia and hypertension could come together, but the d deficiency is unrelated! ...Read more
Can be deadly: Over time, excesses of iron build up in major organs such as the heart, liver, pancreas, joints and pituitary. If the extra iron is not removed, these organs can become diseased, causing conditions like diabetes mellitus, irregular heart beat or heart attack, arthritis, cirrhosis of the liver or liver cancer, gall bladder disease, depression, impotence, infertility, hypothyroidism, hypogonadism. ...Read moreSee 2 more doctor answers
Polycythemia: Polycythemia rubra vera and polycythemia vera are the same thing - a myeloproliferative disorder which causes production of too many red cells (and usually white cells and platelets also). Polycythemia or erythrocytosis just means someone has too many red cells, whether due to prv, high altitude, sleep apnea, emphysema, certain cancers, or certain congenital abnormalities of red cell production. ...Read more
Polycythemia: Polycythemia is a terminology used for a condition where your hemoglobin is elevated above the normal range.It does not tell you what the cause of the condition- which could be caused by a primary bone marrow problem -( which is called polycythemia rubra vera -abbreviated as polycythemia vera) vs some other secondary conditions such as chronic lung problem, sleep apnea, liver mass/renal mass et. ...Read more
To the extent that: P vera would be associated with increased rbc turnover, a modest increase in bili is possible. However, the disease is one of proliferation more than destruction, so if the bili is quite high we need to evaluate. ...Read more
Low serum iron 36 and very high ferritin level 1,171. Is this anemia of chronic disease? High liver enzymes and ALP 476. What's wrong?
Need more info: A complete history is needed! What other Med problems u have? The possibilities are many: anemia w elevated ferritin and normal MCV could be chronic disease. The elevated liver enzymes need imaging and if hep B and C were r/out, maybe a liver biopsy. Many chronic conditions like Rheumatoid arthritis,Lupus, autoimmune liver disease, may cause these findings. Did you mean Alfa fetoprotein?.see PCP ...Read more
Yes,it can cause.: In addition to the prolems of thromosis from excess cellular volume , patients have general symp. Such as fatigue-in nearly 80 percent of people, generalized itching, night sweats, fever , bonepain, and weight loss. Any type of cancer whether blood related or not-like lung , breast cancer patients have symptoms have weight loss, fatigue as cels proliferate in great numers in a short period. ...Read more
Variable: Hi Great question, there's a deeper answer, but generally leukemias usually affect the white blood cell line, rather than the red blood cell lineage. What you're probably referring to is called "anemia of chronic disease". Elevated inflammatory mediators, like IL-6, impair both production and ability to incorporate iron into heme, which causes normocytosis and normochromia. Hope this helps ...Read more