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Doctor insights on: Hematuria Without Proteinuria In Lupus

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Hematuria and proteinuria reflect a kidney problem?

Hematuria and proteinuria reflect a kidney problem?

Glomerular disease: Blood in the urine can come from the kidney blood vessels (glomeruli) or from any anatomic structure along the pathway from urine formation to its exit from the body. Protein in the urine comes from the nephron, either from the glomerulus spilling protein into the urine, or from protein secretion in the tubules. The presence of blood and protein in the urine indicates a glomerular source. ...Read more

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Dr. Nour Baltagi
119 doctors shared insights

Proteinuria (Definition)

Proteinuria means the presence of excess of serum proteins in the urine. The excess protein in the urine often causes the urine to become foamy. Up to 150 mg a day of protein may be excreted by a normal person most of this being tamm-horsfall protein. Between 150-300 mg/day may be considered microalbuminuria and greater than 300mg/day is abnormal and ...Read more


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Why nephrotic syndrome cause massive proteinuria but no hematuria?

Why nephrotic syndrome cause massive proteinuria but no hematuria?

See below: Nephrotic syndrome can be caused by many diseases . Diseases such as diabetic nephropathy, membranous gn, fsgs may cause nephrotic syndrome hematuria and proteinuria occur in eg lupus nephritis the prescence of only proteinuria helps the clinician narrow down to certain diseases before resorting to a biopsy. ...Read more

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I'm having infrequent but recurrent gross hematuria. Tests show proteinuria/mucus but no blood. All other tests normal findings. Cysto scheduled. ?

I'm having infrequent but recurrent gross hematuria. Tests show proteinuria/mucus but no blood. All other tests normal findings. Cysto scheduled. ?

Hematuria: Large intermittent blood loss as you describe can often be ascribed by open bleeding tiny blood vessels. This diagnosis would require a kidney angiogram to localize any blood leak, because they can "plug it up" in radiology. Sometimes you never catch it when it starts bleeding. This is called angiodyspasia, not uncommon. Cystoscopy will look for bladder source of bleeding. ...Read more

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Have lupus.Have had persistent moderate blood in urine (no RBC) for yrs with no known cause. Now have microscopic hematuria (+2-5), with trace protein?

Have lupus.Have had persistent moderate blood in urine (no RBC) for yrs with no known cause. Now have microscopic hematuria (+2-5), with trace protein?

LUPUS: It certainly sounds like prompt follow-up with one of your doctors would be in order; preferably your rheumatologist. If that follow up appointment is going to be delayed, then make an appointment with your primary care Doctor Who can initiate some further testing and evaluation. ...Read more

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How can I have IGA nephropathy with daily microhematuria and proteinuria but a GFR of >90%. Doesn't hematuria always equal kidney damage?

How can I have IGA nephropathy with daily microhematuria and proteinuria but a GFR of >90%. Doesn't hematuria always equal kidney damage?

Not at all: Most patients with kidney disease have normal GFR. The estimated GFR on your lab slip is subscientific anyway. About 75% of IgA neohropathy patients have normal GFR and usually have little trouble. ...Read more

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Have lupus. Moderate microscopic hematuria x months though NO RBC in urine, trace ketones in urine,otherwise normal UA. Total bilirubin 1.6. Thoughts?

Have lupus. Moderate microscopic hematuria x months though NO RBC in urine, trace ketones in urine,otherwise normal UA. Total bilirubin 1.6. Thoughts?

Hemolysis: Lupus is sometimes associated with red cell hemolysis. You may be having this phenomenon. Hemolysis can explain blood in urine and elevated bilirubin. However, you need to discuss the matte with your doctor. ...Read more

Dr. Michael Michaels
614 doctors shared insights

Blood In Urine (Definition)

Hematuria is the presence of blood in the urine. When you can see the blood, it's called gross hematuria. When the blood can only be seen under a microscope it is known as microscopic hematuria. Hematuria can be caused by kidney stones, kidney infections, urinary tract infections, an enlarged prostate, cancer, certain medications, and ...Read more


Dr. Steven Griggs
98 doctors shared insights

Protein In Urine (Definition)

Protein is an expensive commodity for the body. The kidneys are entrusted to return protein back to the body during filtering, and not lose it to the urine. Losses > 150mg/day are indicative of a problem with the filtration mechanism of the kidney. A nephrologist should be consulted ...Read more