Doctor insights on:
Phlebotomy: Typical blood donor can give their donation, typically of 500cc of blood, about once every 8wks. A pt with new diagnosis of severe hemachomatosis may need to donate that much blood 2x/week for a while till the iron level gets down some. Then they can keep measure of the iron level, or ferritin, the nl reference is 50-150ng/ml, and a blood donation schedule is flexible to maintain. ...Read more
I don't think so: It's my humble opinion that any family physician can diagnose and treat common hemochromatosis if someone body can be found to do the blood-bag phlebotomy. A hard-core gastroenterologist, cardiologist, or endocrinologist might disagree especially if the diseases has been missed for a long time and allowed to become advanced. Good luck. ...Read more
In some cases.: Phlebotomy is the first-line treatment for primary hemochromatosis, a genetic defect that makes a person absorb too much iron (hereditary hemochromatosis). It can prolong life expectancy, prevent complications, and relieve some but not all symptoms. Secondary hemochromatosis, which results from repeated blood transfusions, some anemias, or excessive iron therapy, is usually treated w/ iron chelators. ...Read more
What is hemochromatosis & what is the symptom's and treatment - we understand it is heredity, however no one in family effected no more to give
Deadly to miss: Hemochromatosis is a genetic tendency to absorb iron overly well through the gut. This has its plusses but in the long run, in the absence of bleeding or iron loss from periods / pregnancies, too much iron accumulates. The liver failure, diabetes, joint pain at thumb base, dark skin are familiar; it's the easiest really bad disease to treat (drain blood) & folks feel much better. ...Read more
is hemochromatosis reversible through phlebotomy or must a patient undergo phlebotomy on a regular basis for the rest of his life? Does phlebotomy eventually ease the symptom so that this treatment may stop?
Lifelong: Once you get most of the iron out of you, you will require only occasional phlebotomy. You'll monitor it and get treated as you need. ...Read more
Must I have a liver biopsy to confirm a diagnosis of hemochromatosis before I can begin treatment?
My iron serum is 222 (h), iron sat-59 (h), tibc-374, uibc-152.Hereditary hemochromatosis-negative. Need for further treatment? Pcp &gastronologist say no.
Watch it: There are a variety of iron-overload syndromes (the gene that was tested is only the most common of many), and if you'd recently taken an iron tablet this may have something to do with the high iron. I very much doubt that you have hemochromatosis but you can revisit this in a few years without any risk to your health, or consider a serum ferritin now. ...Read more
My mother has been recently diagnosed with hematomacrosis after being misdiagnosed with fibromyalgia. Is it necessary for chemotherapy treatment?
Iron studies panel was abnormal indicating Hemochromatosis. Doc sent me for genetic blood test to confirm. If this is positive, what is the treatment?
Blood letting: The treatment is relatively simple. Periodically, some of your blood is drained out to remove iron along with your red cells. Done regularly it would prevent excess iron accumulation and the usual damage excess iron causes. ...Read more
Is there a treatment or a plan of action for a males pituitary gland damaged by hemochromatosis? My fsh, lh, and testosterone are too low.
Any: Any competent primary care physician can diagnose and arrange for treatment hemochromatosis. You may get sent to the gastroenterologist, cardiologist, endocrinologist and geneticist. The key is that if this is common hemochromatosis, you have the serious disease out of all of them that's easiest to manage effectively. ...Read more
Too much bodily iron: As a result of the inability to increase iron loss, iron overload is an inevitable response to increased iron entry into the body. This can occur by one of three mechanisms - nutritional intake, increased absorption, parenteral sources (i.e. Transfusions). Hemochromatosis is abnormally high absorption of iron as result of a genetic defect. Extra iron can be toxic. ...Read more
1 in 200: It's extremely common, and of all the common, serious diseases, it is the easiest to manage. If it's discovered relatively late, the person realizes they've had "the blahs" for years once phlebotomy removes the excess iron. ...Read more
Can be deadly: Over time, excesses of iron build up in major organs such as the heart, liver, pancreas, joints and pituitary. If the extra iron is not removed, these organs can become diseased, causing conditions like diabetes mellitus, irregular heart beat or heart attack, arthritis, cirrhosis of the liver or liver cancer, gall bladder disease, depression, impotence, infertility, hypothyroidism, hypogonadism. ...Read more
Partly true: The disorder is called hereditary hemochromatosis and it is an autosomal recessive disorder. Meaning it is passed from parent to offspring, people can be carriers of the gene, and you have to have 2 copies of the gene to have the disorder: one from the father and one from the mother. Hemochromatosis is an iron overload which can have other causes than hereditary hemochromatosis though. ...Read more
Iron: 400 characters aren't enough; there are websites, books and journal articles. These folks absorb iron too easily through the gut, and it ends up in the liver, heart, and endocrine pancreas where the atoms generate free radicals that do damage. ...Read more
Inherited: Most primary hemochromatosis is passed parent-to-child, especially if each parent supplies one defective gene, though people with a single dose may be affected. If you're not familiar with basic genetics, you need to become familiar with the terminology as it's basic to life and understanding health and disease in the 21st century. ...Read more
Yes: A good screen for common hemochromatosis is the transferrin saturation, the ratio of iron to iron binding capacity in the blood. Liver enzymes will also be drawn. More than 50% in a woman or 60% in a man is suggestive; follow-up may include serum ferritin, a more costly blood test which if much elevated confirms the diagnosis. ...Read more
A few: Lack of energy, abdominal pain, memory fog, loss of sex drive, heart flutters, irregular heart beat. When symptoms are associated with hemochromatosis, these usually begin in men in their late 20’s to early 30’s. In women, symptoms usually start about 10-15 years after they stop having a period due to menopause, birth control pills or hysterectomy. ...Read more
Yes: Over time, excesses of iron build up in major organs such as the heart, liver, pancreas, joints and pituitary. If the extra iron is not removed, these organs can become diseased, causing conditions like diabetes mellitus, irregular heart beat or heart attack, arthritis, cirrhosis of the liver or liver cancer, gall bladder disease, depression, impotence, infertility, hypothyroidism, hypogonadism. ...Read more
Yes: Hemochromatosis is caused by genetic predisposition to excessive iron storage. It can be treated with removal of iron- usually by recurrent phlebotomy. If you mean spontaneously go into remission, then usually no, it cannot without treatment. In some cases, though, the iron transport/ storage is facilitated by excess alcohol use- in that situation stopping alcohol will improve things. ...Read more
Labs and Bx: Labs that include ferritin and transferrin saturation. All patients being evaluated for hhc should have c282y and h63d mutation analysis. This may help in determine risk for hhc but is not always diagnostic by itself. Lastly a liver biopsy with a iron index or MRI may help to confirm suspected cases. ...Read more