Doctor insights on:
Help Me With Understanding Agonist And Antagonist Drug Actions
Stimulating vs block: Agonists are stimulators of receptors and antagonists are blockers of receptors. ...Read more
What happens if a certain poison/drug blocks the receptor site for a particular neurotransmitter, is it considered an agonist or an antagonist?
Could be either: We have both excitatory neurotransmitters (such as glutamate, glycine), and many inhibitory neurotransmitters (norepinephrine, acetylcholine, dopamine, serotonin), and some agents can interfere by imbalancing the homeostasis. However, mechanistically, receptor blockers really cannot be considered in either category. ...Read more
Can you tell me how is it possible that buprenorphine and butorphanol are partial agonists-antagonists?
Agonist/antagonist: They are agonists at some receptor types and antagonist at other receptor types. Also agonist/antagonist effects may also be dose dependent as well. ...Read more
Can I take remeron and guanfacine together? Remeron is an a2 antagonist and guan is an a2 agonist. Would these compliment each other or cancel out?
Well ...: These 2 medicines would not be an ideal combination as they do interact as you mentioned. Mainly you'd be concerned about a dystegulation on your blood pressure. There are a lot safer & frankly better alternatives out there - depending on what you're taking them for. Always better safe than sorry ... Hope that helps! ...Read more
What do you advise if I've read that salbutamol is a b2 adrenergic receptor agonist but shouldn't it be an antagonist?
Partial agonist: I hope the concept isn't unfamiliar to you. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC473898/ ...Read more
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