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Doctor insights on: Hcv Genome Sequence

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Dr. Camilla Graham
774 doctors shared insights

Hepatitis C (Definition)

An infection caused by the hepatitis C virus that attacks the liver and ...Read more


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What is the human genome project and whose genome was sequenced?

What is the human genome project and whose genome was sequenced?

Map of Human DNA: The Human Genome Project created a map of human DNA and was completed in 2003. Anonymous samples were donated by several people, but the majority of the "genome map" is from a single male donor from Buffalo, NY. The identity of this individual is not known by researchers who sequenced the DNA. ...Read more

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Advia hep. C antibody +,HCV RNA -. 3 months later Architect hep. C antibody -, HCV RNA -. 2 hep C Ab Verification tests-.Can above person donate blood?

Advia hep. C antibody +,HCV RNA -. 3 months later Architect hep. C antibody -, HCV RNA -. 2 hep C Ab Verification tests-.Can above person donate blood?

May be: You ought to disclose these results to the blood bank so that they may make a determination on your eligibility to donate along with other health factors. I commend you for considering doing your civic duty. ...Read more

Dr. John Fung Dr. Fung
3 doctors agreed:
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Hep B Virus (HBV) DNA Qualitative (Detection) - COBAS TaqMan , Hep C RNA Detection by Taqman detection will be conclusive on 47 days? Any retest need?

Dr. John Fung Dr. Fung
3 doctors agreed:
Hep B Virus (HBV) DNA Qualitative (Detection) - COBAS TaqMan , Hep C RNA Detection by Taqman detection will be conclusive on 47 days? Any retest need?

No: Both Hepatitis B and C viruses may be detected 30 to 60 days after infection by antigen detection or 60-120 days with antibody testing. Direct HBV DNA and HCV RNA testing can potentially detect infection earlier, within 2-4 weeks after infection, so being tested at 47 days post-exposure with a negative nucleic acid test for both is very likely to be a true negative ...Read more

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Is it possible to hav all 3 - P24 antigen, HIV antibodies & HIV DNA undetectable at 4 MONTHS of risky exposure? Did 4th gen(Ab/Ag) & PCR DNA together

Is it possible to hav all 3  - P24 antigen, HIV antibodies & HIV DNA undetectable at 4 MONTHS of risky exposure? Did 4th gen(Ab/Ag) & PCR DNA together

Get over it, Bill: You are not infected. I'm glad. You need to find a way of getting these obsessive thoughts out of your head, for your sake and the sake of those who love you. Get on with your life, a better and more mature man for what you went through. ...Read more

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Advia hep.C antibody +, HCV RNA -. 3 months later Architect hep C Ab -, HCV RNA -. 2 Hep C Ab Verification tests -.Is Advia hepC Ab test false positiv

Advia hep.C antibody +, HCV RNA -. 3 months later Architect hep C Ab -, HCV RNA -. 2 Hep C Ab Verification tests -.Is Advia hepC Ab test false positiv

Without more info: and only the data you submitted in your question, I would put it together the way you did: the first Advia hepC Ab test was a false positive. I presume other experts who arranged your follow-up testing have suggested the same interpretation. Stay well:) ...Read more

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Hep B surface Ab - positive, Hep BE antigen - positive, Viral DNA 2000 IU. Acute Hep B DX. Tests don't match the serology timeline? Am I in recovery?

Hep B surface Ab - positive, Hep BE antigen - positive, Viral DNA 2000 IU. Acute Hep B DX. Tests don't match the serology timeline? Am I in recovery?

Need expert care: This situation is too complex for safe advice on this forum. You should be seeing an expert in person, or perhaps seek HealthTap's concierge service with an infectious diseases or liver disease expert. ...Read more

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Etiology of DNA mutations?

Etiology of DNA mutations?

Replication error: Most changes in dna come from errors in the duplication of the dna. But changes can occur in the structure from radiation and some chemicals especially those used in chemotherapy. Most mutations are harmless, some are tracked down by your normal reparative mechanism but a few can cause trouble including cancer. ...Read more

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How do dna, mutation, genotype, phenotype, and natural selection interconnect to cause evolution?

How do dna, mutation, genotype, phenotype, and natural selection interconnect to cause evolution?

Modern synthesis: It's as well-established as anything in science, but would take more than 400 characters to explain. You owe it to yourself, as an educated person who must participate in community decision making, to understand it. There are a huge number of good books on the subject. Best wishes. ...Read more

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HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative. Need any medication or vaccine?

HBV test results: Hepatitis B Surface Antigen: Nonreactive; Hepatitis B Core Antibodies: Reactive; HBV PCR: Negative.  Need any medication or vaccine?

Excellent question: and your story stumps many a doctor, often! :) a lot of the recommendations depend on - are you someone with risk factors for HBV? is this the first time that it has been checked? are your liver enzymes normal? are you about to undergo any procedures/ treatments that could put you at risk for HBV? If you have no sig risk factors, yes, I'd vaccinate you if there's potential for exposure. ...Read more

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Hepatitis b antibody.Standard 5 item HBV test, only HBV surface antibody present. How immune is this to a partner of HBV carrier status through sex?

Hepatitis b antibody.Standard 5 item HBV test, only HBV surface antibody present. How immune is this to a partner of HBV carrier status through sex?

Foolish: If someone is actively and acutely infected with hep b, even the idea of considering unprotected sexual intercourse is ridiculous. Just because immunization status shows immunity to hep b, this is not a 100% guarantee and there are still risks. ...Read more

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Results: Hep C quant. : 2,802,680 HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Results: Hep C quant. : 2,802,680 
HCV log10: 6.448. Reflex to genotype was unable to determine genotype even though there was sufficient HCV RNA?

Hepatitis C virus: Sometimes it's not possible to determine the genotype of this virus, which thus makes the expected response to treatment more uncertain. This is a 'slippery virus' -there are 11 major genotypes (designated 1-11), and many subtypes (a, b, c, etc.) A hepatologist (GI subspecialist) or an ID doctor who works with Hep C patients can help you. You'll need an established relationship for treatment... ...Read more

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Hbsag & hav IgM (elisa)= +, hev igm, leptospiral igm, anti HCV & hb core IgM (elisa)=-, sgot & sgpt were 2332, 4874 initially.Now 52.9 & 186.1 my status?

Hbsag & hav IgM (elisa)= +, hev igm, leptospiral igm, anti HCV & hb core IgM (elisa)=-, sgot & sgpt were 2332, 4874 initially.Now 52.9 & 186.1 my status?

Acute hepatitis A: These data are difficult to follow, but i think these labs mean the following: you have chronic hepatitis b (hbsag+) and got acute hepatitis a on top of that. Your liver enzymes are now returning to normal. If this is true, you will not get hepatitis a again, but need evaluation for hepatitis b. ...Read more

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Monotest (target values <1.0=negativ). Values: EBV VCA IgG-Ak 39.9; EBV VCA IgM-Ak 1.1; EBNA-1 IgG-Ak 14.7; EBV DNA (PCR) negativ. What does it mean?

Monotest (target values <1.0=negativ). Values: EBV VCA IgG-Ak 39.9; EBV VCA IgM-Ak 1.1; EBNA-1 IgG-Ak 14.7; EBV DNA (PCR) negativ. What does it mean?

Ask who ordered: The test, but in general, they were suspecting EBV infection/Infectious mononucleosis, which looks negative, the final diagnosis is with the doctor who ordered the blood test. Clinical picture is important, finally we treat patients not lab results, good luck ...Read more

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Which of these 3 hep c antibody screening tests(methodology)is the most accurate: Architect Anti-HCV, Advia Centauer HCV or Roche Eclia?

Which of these 3 hep c antibody screening  tests(methodology)is the most accurate: Architect Anti-HCV,  Advia Centauer HCV or Roche Eclia?

About equal: All three methods are FDA approved and about equally accurate. If you have concern about active Hep C infection, get a Hep C nucleic acid test. For good health - Have a diet rich in fresh vegetables, fruits, whole grains, milk and milk products, nuts, beans, legumes, lentils and small amounts of lean meats. Avoid saturated fats. Drink enough water daily, so that your urine is mostly colorless. Exercise at least 150 minutes/week and increase the intensity of exercise gradually. Do not use tobacco, alcohol, weed or street drugs in any form. Practice safe sex. ...Read more

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Gene expression profiling predicts clinical outcome of breast cancer?

Gene expression profiling predicts clinical outcome of breast cancer?

We're Getting There: In the past, we used anatomic staging alone (tumor size, lymph node involvement) to guide rx. Gene profiling allows us a completely separate measure of prognosis, and, more importantly, can predict who may or may not benefit from different chemotherapy agents. In the future, we will hopefully be able to tailor our rx to the specific cancer being treated: the elusive personalized medicine. ...Read more