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Doctor insights on: Hcg And Down Syndrome

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Is high hCG in early pregnancy (5-6 weeks) and indicator of down syndrome?

Is high hCG in early pregnancy (5-6 weeks) and indicator of down syndrome?

Discuss w/ Dr.: How high? What specifics? Discuss these concerns w/ your OBGYN. I've heard that the increased risk is specifically about a small portion of the hCG called the beta subunit. If that is high, they consider it an increased risk for Down Syndrome. It's not so much a concern early in pregnancy - they usually test for this between 15-18 weeks and it's part of the quad-screening test. I hope this helps. ...Read more

Dr. Kathryn Akin
654 doctors shared insights

Down Syndrome (Definition)

A genetic chromosome 21 disorder causing ...Read more


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Why are high hCG levels an indicator of down syndrome?

Why are high hCG levels an indicator of down syndrome?

See below: As tests were developed to assess the fetal health it was noted that a fetus with down's syndrome had higher maternal HCG levels that a normal child. This came to be part of the test, along with maternal age and ultrasound examination, to asses the risk of having a down's child. ...Read more

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Blood pressure at 138 when sat down, stand up and it drops to 92/62 dizziness and fainting also, what causes this? Bp naturally low so 138 high for me

Blood pressure at 138 when sat down, stand up and it drops to 92/62 dizziness and fainting also, what causes this? Bp naturally low so 138 high for me

Change of BP: Your symptoms sound as if you have orthostatic hypotension (op), which means your BP falls when you stand up. If this is happening often, you need to go to an er and be evaluated. Causes of o could be volume deficit, loss of fluids, or an irregular heart rhythm, among others. Good to an er and get the answer to your question from the physician who examines you. Good luck. ...Read more

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My hCG levels are going up and down progesterone is normal ?

My hCG levels are going up and down progesterone is normal ?

GYN: How pregnant are you? I suggest GYN evaluation with pelvic ultrasound. If you have a viable pregnancy the HCG levels should continue to rise. ...Read more

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I feel like giving up on my insulin and meds my blood sugar ranges from 4 to 15 during the day moods are low not Dr said increase insulin?

I feel like giving up on my insulin and meds my blood sugar ranges from 4 to 15 during the day moods are low not  Dr said increase insulin?

Insulin: You need to maintain a record of your bel for a week or so. Not sure what insulin are you taking but basal dose of lantus is good idea as it is long acting and the variation will be less. this can be topped up with intermediate acting insulin depending on your BGL. discuss with doctor. get referred to a diabetic educator or specialist if not getting on to of things. don't stop the insulin by your. ...Read more

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My father(55)has excessive left leg pain on pressure and when moving followed by back pain.History of rheuma and coccyx "spike".What to do?

My father(55)has excessive left leg pain on pressure and when moving followed by back pain.History of rheuma and coccyx "spike".What to do?

Back pain: The back pain can be caused by muscle strain, spinal stenosis, ruptured disc, nerve impingement ... The treatment depends on the cause of the pain. It seems like your father might have nerve impingement. I recommend him seeking help from a pain management doctor or orthopedic doctor. He might benefit from a comprehensive evaluation and treatment. ...Read more

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With hCG level initially 600 and then up to over 2,000 in 48 hours, will my pregnancy go to term (progesterone 54)? Is there any chance of miscarriage

With hCG level initially 600 and then up to over 2,000 in 48 hours, will my pregnancy go to term (progesterone 54)? Is there any chance of miscarriage

Impossible: I am happy to hear you are pregnant and happy about it. But, you are asking doctors to predict or guess about things that are absolutely impossible to predict or guess about. ...Read more

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Will a vanishing twin (lost at 7 weeks) affect first trimester downs syndrome testing with blood test and ultrasound?

Will a vanishing twin (lost at 7 weeks) affect first trimester downs syndrome testing with blood test and ultrasound?

Vanishing twin: No, it would not affect your test result. Ultrasound would show it for a while, but the developing twin will eventually grow big enough to hide it from view. ...Read more

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Does your carpal tunnel syndrome mostly go away after resting and getting a break?

Does your carpal tunnel syndrome mostly go away after resting and getting a break?

Yes it could: If you have mild to moderate carpal tunnel syndrome, splint or brace may for a while and avoiding repative movments could do it. Thank you. ...Read more

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Diagnosed with high BPM at resting point and chest pain when lying down, what's going on?

Diagnosed with high BPM at resting point and chest pain when lying down, what's going on?

Possibly: Anxiety can cause excess cortisol, os adrenaline secretion which can cause a number of symptoms, including dizziness, lightheadedness, rapid heart beat palpitations, chestpain, headaches, etc. Try calming yourself down by concentrating on slowing down your breathing over a few minutes if this doesn't help, see your primary provider for further evaluation. Good luck! ...Read more

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Cramps in stomach mainly in the morning made worst by caffeine and relieved by lying down. All blood test, ultra sound and h pylori test normal. ?

Cramps in stomach mainly in the morning made worst by caffeine and relieved by lying down. All blood test, ultra sound and h pylori test normal. 
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Possibly stress.: This sounds like a general symptom that might be associated with stress or anxiety, possibly from the tests just done. If the tests were not done, i would have suggested a possible stomach ulcer. I would say relaxation, less caffeine, a bland diet (milk, vegetables), and rest should help a lot. If not, go back to your doctor, and get checked again. ...Read more

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My LMP is 27apr14 and my beta hCG level on 28may14 found 6805.93mIU/mL and on 30may14 is 14798.49mIU/mL. is it normal or doubt of down syndrome?

My LMP is 27apr14 and my beta hCG level on 28may14 found 6805.93mIU/mL and on 30may14 is 14798.49mIU/mL. is it normal or doubt of down syndrome?

Normal: Your HCG levels have appropriately doubled. It is a good sign of a healthy pregnancy. If you are concerned about Down's syndrome, please speak with your doctor regarding early blood tests that will help with diagnosing an abnormal pregnancy like integrated screening or verifi prenatal test. Good Luck! ...Read more

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Can Pfo cause low oxygen levels while exercise. My oxygen levels drops down to about 88 while i am walking, then at rest it goes up to 98?

Can Pfo cause low oxygen levels while exercise. My oxygen levels drops down to about 88 while i am walking, then at rest it goes up to 98?

It can: It can but it shouldn't. Talk to your cardiologist. PFO tend to be small and under low pressure so when you exercise it should not effect things as much. Sometimes there is a pressure reversal and this is not a good sign since it can mean weakening of the heart. ...Read more

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Pulse increases alot even when making little movement, low when lying down and jumps up right when I move? POTS? Have too many other symp to list also

Pulse increases alot even when making little movement, low when lying down and jumps up right when I move? POTS? Have too many other symp to list also

Although this could: be POTS there are several other conditions that could give you similar symptoms and signs. I think a thorough history, physical examination and simple blood work would be useful to be able to help you. Make an appointment with a health care provider and get checked out. ...Read more