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Doctor insights on: Have There Been Any Adverse Interactions Between Femara And Grapefuit

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Have there been any adverse interactions between femara (letrozole) and grapefuit?

Have there been any adverse interactions between femara (letrozole) and grapefuit?

Indirectly: There is a substance in grapefruit that disables the enzyme responsible for metabolizing estrogen in our bodies; therefore, eating grapefruit may increase the body's levels of estrogen. Femara (letrozole) is used to inhibit the production of estrogen in the body as a treatment for hormone-sensitive breast cancer. Therefore, eating grapefruit in these circumstances may counteract what you are treating. ...Read more

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I have been ttcfor about 20 months now. I have had a mc & an ep. I started Clomid (clomiphene) and then femara, but I haven't gotten pregnant in a year. Next step?

I have been ttcfor about 20 months now. I have had a mc & an ep. I started Clomid (clomiphene) and then femara, but I haven't gotten pregnant in a year. Next step?

TTC 20 months: With a prior ectopic pregnancy, the chance of another can be 25%. Please check the fallopian tubes, semen analysis and consider uterine evaluation with ultrasound or saline sonogram. Depending on findings and your age, either ovulation induction and insemination or ivf will be suggested. ...Read more

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Took femara (letrozole) from cycle 5 to cycle 9, got a positive OPK test on cycle 10, been having intercourse every day since cycle 10 and still no sign ovulation?

Took femara (letrozole) from cycle 5 to cycle 9, got a positive OPK test on cycle 10, been having intercourse every day since cycle 10 and still no sign ovulation?

I don't understand: If you're monitoring with OPK, then the positive test is usually taken as meaning ovulation. What are you asking? Or what are you looking for? ...Read more

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I have been prescribed femara (letrozole) and am wondering how most women do on it. The internet blogs are terrifying. Do most gain weight, lose hair, feel tired?

No fear: Yes, some women will gain weight, get thinning hair, most will have bone aches or hot flashes. Some may even lose bone density but overall, Femara (letrozole) is a good drug and its benefits far outweigh side effects. Some go away in time and worse case scenario, they go away if your doc stops the drug. Don't do like the girl in the tv commercial dating a french model. Not all you read in the web is true. ...Read more

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What is the percentage of her2 breast cancer recurring if I stop taking femara (letrozole) which I have been on for 2 1?

What is the percentage of her2 breast cancer recurring if I stop taking femara (letrozole) which I have been on for 2 1?

Talk to your onc: Your oncologist would be the best one to answer this question. It's not a good idea to stop taking med without a discussion with the prescribing physician, especially when cancer is involved. ...Read more

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Hi, i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness?

Hi,  i stopped taking femara (letrozole) two weeks ago - cold turkey and have been having a lot of headaches, dizziness, nausea, muscle and joint pains, tiredness?

Withdrawal: Consult your gynecologist for a better way to discontinue your hormones. Tapering is generally better than abrupt discontinuation of any drug (absent severe immediate toxicity necessitating the discontinuation). ...Read more

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Been having pregnancy like symptoms. Took femara (letrozole) about 3 weeks ago, had blood test for progesterone day 21 level, came back .4 and had ultrasound done which said I ovulated. Could I be pregnant, be having ectopic pregnancy, or miscarrying?

Been having pregnancy like symptoms. Took femara (letrozole) about 3 weeks ago, had blood test for progesterone day 21 level, came back .4 and had ultrasound done which said I ovulated. Could I be pregnant, be having ectopic pregnancy, or miscarrying?

See your physician: Have a bhcg quantatative done, not bhcg qualatative. It would be good to see what your bhcg number is to determine if you are pregnant. Most home preganancy tests are qualatative which tells you if you are pregnant or not. A quantatative test will provide a "number" to indicate "how much" of a product is produced. ...Read more

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What is femara (letrozole)?

What is femara (letrozole)?

Femara (letrozole): Is a non-steroidal aromatase inhibitor used to treat hormonally responsive breast cancer after surgery. Aromatase is an enzyme that converts androgens to Estrogens which then cause cells to divide. By inhibiting this enzyme, less estrogen is formed, hence less cell replication. ...Read more