Doctor insights on:
Hashimotos Disease And Sjogrens Syndrome
Autoimmune disease: The most common symptoms in Sjögren's syndrome are dry eyes and dry mouth because white blood cells get "confused" and attack and destroy glands in the body that make tears, saliva, vaginal secretions, and other secretions.Inflammation in Sjögren's can cause rashes or arthritis, and even liver, kidney or brain disease. Can also cause saliva gland cancer (lymphoma), so getting treated is important.See 1 more doctor answer
Since sjogrens can damage the thyroid would tpo be produced because of sjogrens and cause hashimotos, or is hashi always a separate disease?
Separate diseases: There is a significant co-existence of these two diseases but they are separate diseases. Both are auytoimmune in nature but the presence of sjogren's disease does not cause the development of thyroid antibodies nor the development of hashimoto's.
Confused on meaning of 2ndary sjogrens. Had hashimotos, now have sjogrens. If its not 2ndary to hashi, does this mean 2ndary to ctd?
When secondary sjogrens is diagnosed, can that be secondary to already existing hashimotos, or always secondary to ctd? No diagnosis of ctd yet but +ccp igg
Is sjogrens ever secondary to hashimotos or is it only considered secondary when ctd is present? Is it sjogrens that causes hashi in someone with both
Different: Patients with collagen vascular disease are at high risk for developing autoimmune thyroid disease. By itself, hashimoto's is very common and not usually a foreboding for other autoimmune disease, though risk is somewhat higher than that of general population for other autoimmune problems. Sjogren's and hashimoto's are caused by different antibodies, but both are autoimmune.
One of these forms: Ss related kidney disease would show up in biopsy & lab work on blood & urine: 1. A tubular interstitial nephritis biopsy revealing lymphocytes infiltrating normal surrounding kidney tissue. 2. Dangerous electrolyte imbalances in blood from inadequate acid removal from urine. 3. Blood, protein & other waste products in the urine due to decreased ability of the kidney to filter well.
I was dignosied with chronic iritis, raynaud's disease, chronic dry eyes. Possible sjogrens syndrome. All blood work came normal what should do?
Ophthalmologist: And rheumatologist. Both these physicians should be able to design an effective treatment plan to control your symptoms.See 2 more doctor answers
Autoimmune disease: Sjogrens is an autoimmune disease. This means that the body starts to " attack" itself due to an alteration in the ability to identify its own tissue. It " perceives" the target tissue as a foreign invader and tries to eliminate it. This leads to signs and symptoms of whatever organ is being attacked. Like many autoimmune diseases, there are genetic factors that predispose someone to be affected.
Cure/Sjogren Syndrom: No there is no cure for sjogren syndrome but it can go into remission in some cases, some mild cases can be handled with symptomatic therapy. With proper attention to eyes and oral care patients are able to be comfortable.Dry eyes can cause trauma to eyes and corneal obesity, so all patients should be under care of eye doc, dry mouth needs to be handled by dentist to prevent tooth deacay.
Combination of meds: Treatment starts with daily oral steroids (prednisone)to gain faster control of inflammation followed by "steroid-sparing"meds that control systemic autoimmune disease without the long term serious side-effects of steroids so steroids can be decreased and then stopped. These safer long-term drugs are low dose Methotrexate weekly, imuran, cellcept, (mycophenolate mofetil) and rituximab. Plaquenil is given to prevent flares.See 1 more doctor answer
An autoimmune diseas: Sjögren's is an autoimmune disease where the body "turns against itself" and makes antibodies against the mucous secreting areas of the body- the eyes mouth respiratory and genitourinary it is mostly associated as the dry eyes dry mouth syndrome. Other features may include arthritis and kidney disease. It is vital that you see a rheumatologist to evaluate yourcsymptoms make the correct diagnosis a.See 1 more doctor answer
Bx and lab.: I do minor salivary gland bx, and really heavily on lab tests, looking for the presence of ss-a and ss-b autoantibodies. Almost 50% of sjogren's patients have a positive rf. Eelvations of gammaglobulins are common, especially IgG and igm. There is some heredebiity to this condition, albeit weaker than many forms of arthritis.See 1 more doctor answer
Sjogren's: Sjogren's is the most common of the (so called) connective tissue diseases in the lupus family. Ucsd and scripp's cliic researches suggest on the basis of autoimmine blood tests run on blood donors, 1/300 may have it, although it is closer to 1/500. Variable in severity, it causes loss of water secretions in mouth, eyes, colon, even perspiration, with time. Associated with ss-a, b antibodies.
There are many: Sjogrens syndrome most often is a benign condition in the sense that it usually doesn't cause serious internal organ damage. However, it can cause severe dry mouth leading to dental problems, dry eyes leading to corneal abrasions, vaginal dryness leading to painful intercourse. It can also have more serious consequences with skin, nerve, lung, heart, joint, bone marrow, and other organ injury.
Carious Lesions: Xerostomia is one of the components of sjogrens syndrome. The best thing to do would be supplement your oral hygiene regimen with Fluoride based agents and if you want to be proactive xylitol based gums, rinses etc would be helpful in keeping you cavity free. See your dentist for regular checkups.See 2 more doctor answers
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