Doctor insights on:
Halfan Anti Malaria Agent
How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?
Chloroquine: Chloroquine concentrates up to several 1000-fold in the food vacuole of the parasite. Possible mechanisms for this selective accumulation of Chloroquine in the food vacuole are: 1) protonation and ion trapping of the Chloroquine due to the low ph of the food vacuole; 2) active uptake of Chloroquine by a parasite transporter(s); and/or 3) binding of Chloroquine to a specific receptor in the food va. ...Read moreSee 1 more doctor answer
The word comes from italian "mala aria" (bad air), from the belief the disease was caused by unhealthy air in swampy districts. Spread by mosquitoes, the parasite enter the bloodstream & infect red blood cells causing high fever, shaking chills, sweats, vomiting, muscle pain, headache, anemia. First symptoms occur 10 days to 4 weeks post infection, symptoms occur in cycles of ...Read more
What do you advise if I'm traveling to uganda for three months and want to know which anti-malaria pills are the best to take?
Anti-malaria pills: There are several antimalarial drugs that are available. You & your doc can decide on the best drug for you - based on travel plans, medical history, age, drug allergies, pregnancy status, & other factors. Make sure to allow enough time for some of the drugs to become effective and for a pharmacy to get these meds. Travel medicine or ID specialists can help. Don't forget - AVOID the BITE! ...Read more
Cancel your trip: The best alternative to malaria prophylaxis in an endemic area is to cancel your trip. I once met a traveler who tried to prevent malaria in a hot tropical country by wearing long sleeve shirts and long pants and by eating lots of raw garlic. Not only was he an unpopular travel companion, but he ended up in the hospital with cerebral malaria. ...Read more
Malaria in the world: First, the location of the risk for malaria must be known. Some meds do not work in some areas in the world. So first knowing your risks and what meds work in that locale is vital. Then the meds can be evaluated for safety in pregnancy. Here is a website to learn about malaria risks where you are or are going: http://www.Cdc.Gov/travel. ...Read moreSee 1 more doctor answer
Generic ok: Pharmacist can dispense generic version of same drug prescribed automatically in most states, a full sub can be done on the permission of your doctor. ...Read more
Yes: If taking prophylactic anti-malarials is not possible then the best way to avoid getting malaria is to use insect repellents on your skin which contain deet, insect repellants on your clothing which contain permethirn, sleep under a bed net and avoid being outside at dusk when the mosquitoes which transmit malaria are most likely to bite. ...Read more
One phone call away: On your bottle of medicine, is a phone number. You can ask the pharmacist where you got the medicines if they are ok to take together. ...Read more
I am taking a anti malaria medication as I am going on a trip it says that other vaccines be not be as effective.Was prescribed dukoral.Can i take it?
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