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Doctor insights on: Halfan Anti Malaria Agent

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How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

How does the antimalarial chloroquine work? Does it passively diffuse into red blood cells to thwart the malaria parasite or does it enter the red blood cells by an active transport process?

Chloroquine: Chloroquine concentrates up to several 1000-fold in the food vacuole of the parasite. Possible mechanisms for this selective accumulation of Chloroquine in the food vacuole are: 1) protonation and ion trapping of the Chloroquine due to the low ph of the food vacuole; 2) active uptake of Chloroquine by a parasite transporter(s); and/or 3) binding of Chloroquine to a specific receptor in the food va. ...Read more

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Dr. Heidi Fowler
355 doctors shared insights

Malaria (Definition)

The word comes from italian "mala aria" (bad air), from the belief the disease was caused by unhealthy air in swampy districts. Spread by mosquitoes, the parasite enter the bloodstream & infect red blood cells causing high fever, shaking chills, sweats, vomiting, muscle pain, headache, anemia. First symptoms occur 10 days to 4 weeks post infection, symptoms occur in cycles of ...Read more


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Can too much anti-malaria drug cause miscarriage?

Can too much anti-malaria drug cause miscarriage?

Yes,: A pregnant shouldn't as a general rule take no medication, illicit or not during pregnancy, especially during the first trimester. One glass of wine with dinner not a problem. If there is a compelling need to use a drug, the benefit vs the risk must be weighed by a specialist (high-risk obstetrician). If your planning travelling to an endemic malaria part of the world---fagetaboutit, seriously! ...Read more

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When does someone need the anti-malaria vaccine? Does it only work if taken before exposure to malaria?

When does someone need the anti-malaria vaccine? Does it only work if taken before exposure to malaria?

Future hope: Currently there is no vaccine for malaria although many are searching for this with some promising leads. There are medication s which can attack the malaria organism and deal with active infection and some that prevent the malaria from spreading if you are exposed. Hopefully a vaccine will eventually be developed. ...Read more

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What are the alternatives to anti-malaria pills?

What are the alternatives to anti-malaria pills?

Cancel your trip: The best alternative to malaria prophylaxis in an endemic area is to cancel your trip. I once met a traveler who tried to prevent malaria in a hot tropical country by wearing long sleeve shirts and long pants and by eating lots of raw garlic. Not only was he an unpopular travel companion, but he ended up in the hospital with cerebral malaria. ...Read more

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Can i take pain reliever tablet while taking anti malaria drug?

Can i take pain reliever tablet while taking anti malaria drug?

One phone call away: On your bottle of medicine, is a phone number. You can ask the pharmacist where you got the medicines if they are ok to take together. ...Read more

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Is there an alternative to malarone (atovaquone and proguanil) / other anti-malaria tablets?

Yes: If taking prophylactic anti-malarials is not possible then the best way to avoid getting malaria is to use insect repellents on your skin which contain deet, insect repellants on your clothing which contain permethirn, sleep under a bed net and avoid being outside at dusk when the mosquitoes which transmit malaria are most likely to bite. ...Read more

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I am taking a anti malaria medication as I am going on a trip it says that other vaccines be not be as effective.Was prescribed dukoral.Can i take it?

I am taking a anti malaria medication as I am going on a trip it says that other vaccines be not be as effective.Was prescribed dukoral.Can i take it?

Yes: Typhoid vaccine should be separate 8 hours from dukoral for it can decrease the effectiveness of the vaccine. Chloroquine decreases the effects of dukoral but is felt to be a minor effect. ...Read more

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I recently travelled to Nigeria. I have a few bites on my feet and leg. As I travel so often for work I did not take anti malaria. Should I get check?

Consider: "If you feel sick and think you have malaria especially if you have a fever up to 1 year of travel, go to Doctor" CDC. Malaria is a very serious disease with fatal consequences.Go review the CDC. Next time please take the prophylaxis as recommended! ...Read more

Halofantrine (Definition)

Halofantrine is an anti-malaria agent which is a kind ...Read more


Halfan (Definition)

Halfan is an anti-malaria agent which is a kind ...Read more