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Doctor insights on: Guillain Barre Syndrome Pathophysiology

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Can you die from guillain-barre syndrome?

Can you die from guillain-barre syndrome?

Yes: This is a rapid onset paralysis of muscles starting in the legs and rapidly involving upper trunk and breathing in the worst cases. You could die from inability to breathe. If this is occurring, get to the er as fast as possible. ...Read more

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Dr. Daniel Saurborn
113 doctors shared insights

Guillain Barre Syndrome (Definition)

A disorder in which the body's immune system attacks part of the peripheral nervous system. The first symptoms of this disorder include varying degrees of weakness or tingling ...Read more


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What are the tests for guillain-barre syndrome?

What are the tests for guillain-barre syndrome?

Guillain-Barre: Is a form of ascending paralysis which has several major forms and can result in long term persistent neurological deficits. There is a recent excellent review of this illness in the new england journal of medicine. Look online. ...Read more

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What are the symptoms of guillain-barre syndrome?

What are the symptoms of guillain-barre syndrome?

Motor weakness: Guillian-barre is an inflammatory disease of the nerve roots that results in pain and progressive motor weakness. It can cause paralysis, breathing failure and problems with the cardiovascular system. If it is suspected, it should be evaluated and treated emergently. Proper treatment can be lifesaving and result in full or near full recovery. ...Read more

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How to know if I have guillain-barre syndrome or something else?

Response: Why did you ask this question? Do you have progressive ascending weakness which has started a few days ago? If so, get to a hospital ASAP, you are at risk. Sorry, I have no clue what "something else" is!! ...Read more

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Think I may have guillain barre syndrome again or what is going on?

Guillain-Barre: Is a form of ascending paralysis which has several major forms and can result in long term persistent neurological deficits. There is a recent excellent review of this illness in the new england journal of medicine. Look online. ...Read more

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Can guillain-barre syndrome be fatal?

Yes: Guillain barre causes ascending paralysis. If the paralysis gets to the muscle of breathing, then breathing may stop. Some patients need to be on a ventilator to save their lives. If the paralysis happens too quickly or ventilation is not available, the patient will die. However, if full support is provided, full recovery is expected back to normal. ...Read more

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What causes guillain-barre syndrome (gbs)?

What causes guillain-barre syndrome (gbs)?

No one knows: Gbs occurs when the bodies immune system attacks the lining or myelin of the nerve cells in the peripheral nervous system. Although it can be associated with things like following surgery or after certain infections, for example it has been seen following campylobacter infection which causes diarrhea, the true cause is unknown. ...Read more

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Guillain barre syndrome--what is the reason you get it?

Guillain barre syndrome--what is the reason you get it?

Autoimmune: Our best understanding is that the body's immune system reacts against a new antigen (usually after a viral infection but this isn't always possible to identify). The newly primed immune system then inappropriately attack's the body's nervous system leading to the syndrome. ...Read more

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Can guillain Barre' syndrome lead to mesothelium gravis?

No: These are two discreet clinical entities. One causes demyelination of the peripheral nerve due to an autoimmune response the other causes an antibody mediated response on the acetylcholine receptor on the nerve muscle junction. ...Read more

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How are campylobacteriosis and guillain-barre syndrome different?

How are campylobacteriosis and guillain-barre syndrome different?

Campylobacteriosis: Is the bacterial infection that can, very rarely, lead to a neurologic disease, guillain-barre syndrome (gbs) that causes demyelination and neuronal issues with subsequent weakness. The bacteriosis is only the bacterial infection, where gbs is the neurologic aftermath people can get from possibly autoimmune attack on there nerves. ...Read more

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Which peripheral nerves are affected with guillain barre syndrome ?

Which peripheral nerves are affected with guillain barre syndrome ?

Affected nerves are:: Any peripheral sensory-motor branch of nerves that affect the anterior musculature of the leg and foot. Becuase gb causes upper motor nerve disruption of muscular function, the most affected nerves are those in the lower leg and foot that are part of the "swing" phase of gait, namely the extensor muscle of the foot and anterior tibialis muscle. The nerve roots affected are l3-l4-l5-s1. ...Read more

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Can anyone tell me about the side effect of the guillain-barre syndrome?

Guillain-Barre: Is a form of ascending paralysis which has several major forms and can result in long term persistent neurological deficits. ...Read more

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I did a search for diagnosis of some of my symptoms and came up with guillain-barre syndrome. What do doctors look for to diagnose it?

I did a search for diagnosis of some of my symptoms and came up with guillain-barre syndrome. What do doctors look for to diagnose it?

Guillain-Barre syndr: Guillain-barre syndrome is a post-viral disease where antibodies attack the lining of the nerves. The longest nerves get affected first--i.e., the nerves to the hands and feet. You may feel some numbness, but the hallmark sign is weakness, ultimately inability to walk. Symptoms are progressive and ultimately if the diaphragm muscle gets weak you will have trouble breathing. ...Read more

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Neuro docs, please someone read my guillain barre syndrome symptom description & please advise what your thoughts are on possible diagnosis-thank you!

Response: Not clear to me why you have "muscle weakness", and your information does not indicate why you wonder about Guillain-Barre. This is far better handled by reviewing your medical profile, which can be done via an INBOX consult or a Concierge virtual visit. ...Read more

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Guillain barre syndrome connected to eczema?

Guillain barre syndrome connected to eczema?

No connection: There is no relationship between guillain barre syncroe and eczea. ...Read more

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What is the treatment for guillain barre syndrome?

What is the treatment for guillain barre syndrome?

See below:: Treatment of guillain-barré syndrome may include plasma exchange (plasmapheresis) and high-dose immunoglobulin therapy. A respirator may be used if the patient requires assistance to breathe. Physical therapy can begin after the patient recovers limb control.The recovery period: a few weeks or as long as a few years. About 30% may suffer from residual weakness after 3 years. ...Read more

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What are signs of guillain barre syndrome?

Acute neuritis: An ascending rapidly progressive weakness then paralysis, starting typically bilaterally in legs, later arms and hands, and later yet issues with swallowing and breathing, often following influenza, but also seen with infectious mono, some GI infections, and could lead to respiratory collapse if not properly treated. ...Read more

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Good place to treat guillain-barre syndrome?

Good place to treat guillain-barre syndrome?

See below: Any large teaching or community hospital can treat a patient with gbs if they offer the following capabilities: neurologic consultation 7 days/week, a neurologic ICU or med ICU familiar with neurologic patients/complications, ICU pharmacy that can provide ivig 7 days a week and/or Albumin for plasmapheresis 7 days/week, experienced pt, ot, speech & respiratory therapists, and good rehab. That's all. ...Read more