Doctor insights on:
Guillain Barre Syndrome Pathophysiology
Motor weakness: Guillian-barre is an inflammatory disease of the nerve roots that results in pain and progressive motor weakness. It can cause paralysis, breathing failure and problems with the cardiovascular system. If it is suspected, it should be evaluated and treated emergently. Proper treatment can be lifesaving and result in full or near full recovery. ...Read more
Yes: Guillain barre causes ascending paralysis. If the paralysis gets to the muscle of breathing, then breathing may stop. Some patients need to be on a ventilator to save their lives. If the paralysis happens too quickly or ventilation is not available, the patient will die. However, if full support is provided, full recovery is expected back to normal. ...Read moreSee 1 more doctor answer
No one knows: Gbs occurs when the bodies immune system attacks the lining or myelin of the nerve cells in the peripheral nervous system. Although it can be associated with things like following surgery or after certain infections, for example it has been seen following campylobacter infection which causes diarrhea, the true cause is unknown. ...Read moreSee 1 more doctor answer
Campylobacteriosis: Is the bacterial infection that can, very rarely, lead to a neurologic disease, guillain-barre syndrome (gbs) that causes demyelination and neuronal issues with subsequent weakness. The bacteriosis is only the bacterial infection, where gbs is the neurologic aftermath people can get from possibly autoimmune attack on there nerves. ...Read more
Affected nerves are:: Any peripheral sensory-motor branch of nerves that affect the anterior musculature of the leg and foot. Becuase gb causes upper motor nerve disruption of muscular function, the most affected nerves are those in the lower leg and foot that are part of the "swing" phase of gait, namely the extensor muscle of the foot and anterior tibialis muscle. The nerve roots affected are l3-l4-l5-s1. ...Read more
I did a search for diagnosis of some of my symptoms and came up with guillain-barre syndrome. What do doctors look for to diagnose it?
Guillain-Barre syndr: Guillain-barre syndrome is a post-viral disease where antibodies attack the lining of the nerves. The longest nerves get affected first--i.e., the nerves to the hands and feet. You may feel some numbness, but the hallmark sign is weakness, ultimately inability to walk. Symptoms are progressive and ultimately if the diaphragm muscle gets weak you will have trouble breathing. ...Read moreSee 1 more doctor answer
See below:: Treatment of guillain-barré syndrome may include plasma exchange (plasmapheresis) and high-dose immunoglobulin therapy. A respirator may be used if the patient requires assistance to breathe. Physical therapy can begin after the patient recovers limb control.The recovery period: a few weeks or as long as a few years. About 30% may suffer from residual weakness after 3 years. ...Read more
Acute neuritis: An ascending rapidly progressive weakness then paralysis, starting typically bilaterally in legs, later arms and hands, and later yet issues with swallowing and breathing, often following influenza, but also seen with infectious mono, some GI infections, and could lead to respiratory collapse if not properly treated. ...Read more
See below: Any large teaching or community hospital can treat a patient with gbs if they offer the following capabilities: neurologic consultation 7 days/week, a neurologic ICU or med ICU familiar with neurologic patients/complications, ICU pharmacy that can provide ivig 7 days a week and/or Albumin for plasmapheresis 7 days/week, experienced pt, ot, speech & respiratory therapists, and good rehab. That's all. ...Read more
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