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Doctor insights on: Guillain Barre Syndrome Pathophysiology

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How come I had guillain-barre syndrome, but nobody else in the family has ever had it?

How come I had guillain-barre syndrome, but nobody else in the family has ever had it?

Not familial: Gbs is a postinfectious, immune-mediated disease. Cellular and humoral immune mechanisms probably play a role in its development. Most patients report an infectious illness in the weeks prior to the onset of gbs. Epidemiological studies have failed to demonstrate a familial connection or predilection for the syndrome. ...Read more

Dr. Eric Weisman
101 doctors shared insights

Guillain Barre Syndrome (Definition)

French neurologists described a condition of progressive weakness following an illness. First by guillain and barre then added to by landray and stohl describing more severe forms with respiratory paralysis. Most cases progress up legs to trunk to arms, then slowing recover to normal. Some affect breathing, swallow and facial movement. Some with dizziness and ...Read more


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How fully do you expect I will recover from guillain-barre syndrome?

How fully do you expect I will recover from guillain-barre syndrome?

Depends: There is no telling how you personally will recover. It depends on the degree of damage done to your nerves and muscles. Some changes may be irreversible. You may want to consult with a neurologist who may suggest nerve congestion study and electromyography to evaluate the degree of damage and the potential for reversal. ...Read more

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Can you die from guillain-barre syndrome?

Can you die from guillain-barre syndrome?

Yes: This is a rapid onset paralysis of muscles starting in the legs and rapidly involving upper trunk and breathing in the worst cases. You could die from inability to breathe. If this is occurring, get to the er as fast as possible. ...Read more

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What is the long-term outlook for those with guillain-barre syndrome?

What is the long-term outlook for those with guillain-barre syndrome?

Very Good: Around 80% of people who contract guillain-barre will go on to make a full-recovery and live a normal life. About 10% will have some sort of long-term disability, such as motor or sensory nerve damage or recurrent episodes. Those with recurrent episodes are classified as having chronic inflammatory demyelinating polyneuropathy (cipd). ...Read more

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What are the most common symptoms of guillain-barre syndrome?

GBS: Guillain-barre syndrome presents with progressive weakness starting at distal parts of limbs and moving upwards towards the torso. The extremity eventually may become limp. It can also affect the respiratory muscles and the patient my end up on a ventilator in an icu. Other unusual symptoms are changes in heart and blood pressure. ...Read more

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How to know if I have guillain-barre syndrome or something else?

Response: Why did you ask this question? Do you have progressive ascending weakness which has started a few days ago? If so, get to a hospital ASAP, you are at risk. Sorry, I have no clue what "something else" is!! ...Read more

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What are the symptoms of guillain-barre syndrome?

Motor weakness: Guillian-barre is an inflammatory disease of the nerve roots that results in pain and progressive motor weakness. It can cause paralysis, breathing failure and problems with the cardiovascular system. If it is suspected, it should be evaluated and treated emergently. Proper treatment can be lifesaving and result in full or near full recovery. ...Read more

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What is the definition or description of: guillain barre syndrome?

AIDP: This condition goes by several names and has a few variants. Commonly seen is aidp-acute inflmmatory demyelinating polyneuropathy. This is a condition of nerve inflammation affecting primarily the outer casing of the nerves (myelin sheath), is acute in onset, and is usually ascending (feet, upper legs, hands, sometimes face and chest). It can be severe and should be evaluated promptly. ...Read more

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What are the tests for guillain-barre syndrome?

What are the tests for guillain-barre syndrome?

Guillain-Barre: Is a form of ascending paralysis which has several major forms and can result in long term persistent neurological deficits. There is a recent excellent review of this illness in the new england journal of medicine. Look online. ...Read more