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Doctor insights on: Gravis Myasthenia

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What is myasthenia gravis?

What is myasthenia gravis?

Fatigable weakness: Myasthenia gravis is an autoimmune disease that disrupts the neuromuscular junction, so that when motor nerves fire the muscle fibers do not reliably contract. It manifests as a "fatigable weakness" (one that gets worse with sustained effort) that can involve the limbs, the cranial nerves (hoarseness, double vision, difficulty swallowing), or, in some dangerous cases, muscles of breathing. ...Read more

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What causes myasthenia gravis?

Autoimmune: We have discovered that the connection between nerve and muscle is compromised by injury to the neuromuscular junction by an antibody that affects acetylcholine transmission. Thus, for whatever reason, the body immune system is attacking itself. ...Read more

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What is myasthenia gravis and how is it treated?

Immune disorder: Which affects to neuromuscular junction connections of nerve to muscle. Associated with progressive weakness on exertion, and can be associated with double vision, problems breathing, and swallowing. Treatment in past involved, steroids, immune agents, and meds that affect the neurotransmitter acetylcholine. ...Read more

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What increasesrisk for myasthenia gravis?

Wide range of people: Conditions that increase your risk for developing myasthenia include: autoimmune disease (thyroid disease, lupus, rheumatoid, type I diabetes), a tumor called a thymoma, and exposure to certain medications (most famously an immunosuppressant and chelating agent called penicillamine). ...Read more

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How common is Myasthenia Gravis?

Prevalence of MG?: It's estimated that MG is present in between 50-60K individuals in the U.S. It will increase as the age of the population increases. ...Read more

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Is myasthenia gravis hereditary?

Unknown: In most cases, myasthenia gravis is not inherited and occurs in people with no history of the disorder in their family.

About 3 to 5 percent of affected individuals have other family members with myasthenia gravis or other autoimmune disorders, but the inheritance pattern is unknown.

For more info please review the following:
http://www. Myasthenia. Org/whatismg/faqs. Aspx. ...Read more

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How serious is myasthenia gravis?

How serious is myasthenia gravis?

Usually very serious: Myasthenia gravis is typically seen in the young and the elderly. In the latter group, they typically have ocular mg, that is there symptoms are confined to the eye muscles. In the young, symptoms include muscle weakness, breathing difficulties, swallowing difficulties, visual problems (double vision, droopy eye lids), problems chewing. Symptoms worsen during the day. If not treated, it can be fatal. ...Read more

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Who is at risk myasthenia gravis?

Who is at risk myasthenia gravis?

Wide range of people: Myasthenia has been reported in people of all age groups, but it tends to be more common in people aged 50-70 or in women under 40. Conditions that increase your risk for developing myasthenia include: autoimmune disease (thyroid disease, lupus, rheumatoid, type I diabetes), thymoma, and exposure to certain medications (most famously an immunosuppressant and chelating agent called penicillamine). ...Read more

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Who can develop myasthenia gravis?

Women>men: Before the age of 40 mg is 3x more common in women, but at older ages both sexes are equally affected. Familial cases are rare. Congenital mg in children are rarely encountered. Their mothers are asymptomatic, and the condition is often familial. Limb weakness is present but eye movement weakness is the dominant sign. There are also neonatal forms characterized by weak suck, and juvenile forms. ...Read more

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How is myasthenia gravis diagnosed?

How is myasthenia gravis diagnosed?

Myasthenia: An intravenous injection called a tensilon test, blood testing for acetylcholine receptor antibodies, and an electrophysiological test called an electromyelogram can all be used to help make a diagnosis of myasthenia. ...Read more

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What causes mg (myasthenia gravis)?

Immune system: Myasthenia is caused by the immune system attacking a protein in the junction between nerve and muscle. This usually happens spontaneously, but can be triggered by drug exposure or by certain types of tumors. ...Read more

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Will myasthenia gravis ever go away?

MG Remission: Yes remission can occur for several year at a time. ...Read more

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Myasthenia gravis can wayfaring cause mg?

It is not possible: Myasthenia gravis can cause weakness in your neck, arms and legs, other muscles. MG is caused by antibodies blocking acetylcholine, but it is not caused by wayfaring. Take care. ...Read more

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What can I do if I have myasthenia gravis?

See specialist: Myasthenia gravis is a potentially life threatening but treatable condition. It has to be treated by a neurologist preferably one who whose sub specialty is neuromuscular disease. ...Read more

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How will myasthenia gravis affect the body?

Fatigable weakness: The hallmark of myasthenia is "fatigable weakness", meaning that muscles get weaker with prolonged use. Typical symptoms include double vision, droopy eyelids, or weakness of the limbs, all worse with activity or at the end of the day. It can also cause difficulty speaking, swallowing, and breathing, which can be extremely dangerous. ...Read more

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What are the symptoms of myasthenia gravis?

What are the symptoms of myasthenia gravis?

Weakness: Characteristically, it is a disease affecting nerve and muscle connections, and may initially present with double vision, drooping of eyelids, and weakness involving arms and legs. Repetitive usage of muscles can result in increased weakness and increased lid drooping and double vision. If the problem intensifies, difficulty with breathing can occur, and this may become critical. ...Read more

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How do medications treat myasthenia gravis?

Two ways: Some medications are designed to enhance the neuromuscular junction connection, and prolong presence of acetylcholine. Since myasthenia is an autoimmune disorder, steroids and other immune agents can address the underlying causation. ...Read more

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What can you tell me about myasthenia gravis?

Weakness: An immunological disorder of the neuromuscular junction, affecting efficiency of nerve muscle impulses, by making acetylcholine surge ineffective. Repetitive contractions are increasingly weak. May affect eye muscles predominantly, with double vision, and lid drooping, but can also affect arms and legs, and ability to breathe. Thymectomy may help, meds also useful. ...Read more

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What canworsen my myasthenia gravis symptoms?

What canworsen my myasthenia gravis symptoms?

Medications: Infections and medications can cause worionsening og mg. Medications like certain antibiotics, anesthetic agents, muscle relaxants, Botox injections etc. Decrease immune system related to multiple factors like lack of sleep, overexhaustion etc. ...Read more

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What happens in the disease myasthenia gravis?

Block receptor: Increased abnormal activity of the immune system can create antibodies that block communication between nerves and muscles. Specifically the nerve transmitter, acetylcholine (ach) is blocked from activating the ach receptor on muscles, which causes weakness. Mg can be treated by increasing the amount of ach reaching the receptor to overcome the blockade and by controlling the immune response. ...Read more

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Can myasthenia gravis slows down your thinking?

Yes it is possible: Studies in the literature have shown myasthenia gravis can impact cognitive function causing "slowing." please consult with your neurologist if you are having symptoms. Hope that helps! ...Read more

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What diseases are similar to myasthenia gravis?

Muscle weakness: Nerves and muscle disorders can give pictures similar to that of myasthenia gravis especially if the facial muscles and the muscles of the shoulder and pelvic girdle are involved. Please make sure that you have the proper diagnosis for myasthenia gravis. You will need blood tests for antibodies, and repetitive stimulation studies or even single fiber emg. You must be taken care of by a neurolog. ...Read more

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Can you have complete cure of myasthenia gravis?

Yes: Often, people may experience complete remission of mg. The thymus gland is sometimes removed which is believed to help promote complete remission in many people. Best of luck. ...Read more

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What are the main symptoms of myasthenia gravis?

What are the main symptoms of myasthenia gravis?

MG symptoms: Proximal muscle weakness with diurnal variation. Increased weakness of muscles brought by exercise. Periodic eye droop, low hoarse voice, shortness of breath. Not everybody will have all symptoms. ...Read more

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What are the first symptoms of myasthenia gravis?

What are the first symptoms of myasthenia gravis?

Ptosis: Ptosis (droopiness of one or both eyes) or proximal muscle weakness of arm, thigh or neck. ...Read more

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What medications can aggravate myasthenia gravis?

Comments: The best documented problems occur with many but not all -mycin antibiotics, and may be best to avoid Cipro, (ciprofloxacin) Ketek, Z-pak, but also most fluoroquinolones. Stay away from Botox, Quinine, and all beta-blockers. ...Read more

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I would like to know more about myasthenia gravis?

Myasthenia Gravis: Is an autoimmune disease in which antibodies are made against the acetylcholine receptor present at the myoneural junction on skeletal muscle. Symptoms are fatigue-able weakness. It usually occurs in young females and elderly males. ...Read more

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What foods do you recommend for myasthenia gravis?

No magic: Having myasthenia gravis is difficult enough without subscientific / non-evidence-based dietary recommendations. Eat sensibly -- enough protein, avoid very salty / greasy / sugary stuff. Almost all internet advice about particular foods to choose or avoid for particular illness is subscience at best, and primarily entertainment. ...Read more

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What are the typical symptoms of myasthenia gravis?

Muscle weakness: Weakness if the hallmark and this affects many muscles. See rheumatologist if you suspect you may have it. ...Read more

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