Doctor insights on:
Graviola Melanoma Treatment
A condition in which some element of your skin--which is one of the most complex organs in the body--degenerates into cancer. The three most common types of skin cancer are: basal cell, squamous cell, and melanoma which occur in that order and degree of aggressiveness. Although heredity plays a major role, sun exposure and tobacco use and ...Read more
Depend on stage: Surgery is the only curative therapy for early stage melanoma (the 5- and 10-year survivals are: 97% and 95% for stage ia, 92 and 86% for stage ib, 81 and 67% for stage iia, 70 and 57% for stage iib, 78% and 68% for stage iiia, 59 and 43% for stage iiib, 40 and 24% for stage iiic). For stage IV or metastatic disease, cure is rare, and is seen mainly with immunotherapy such as high dose il2 or ipi. ...Read more
Depends: Currently, surgical excision is the standard of care. However, depending on the stage of a patient's melanoma there are some new treatments that may show promise for the future. Vemurafenib is one such treatment, but it is used in a very specific set of patients. Melanoma vaccines are also theoretically possible but have not been very successful to date. ...Read more
This is a condition that requires in many cases agressive care with an oncologist and surgeon team with a special interest with melanoma treatment. Often a University Affiliated program with specific treatment protocols are of beneift.
Seeking a second opinion by an expert that specializes in Melanoma treatment is helpful. ...Read more
Remember your abcd's when thinking of melanoma. Look for moles with
boarders that are irregular
color differences within the same mole
diameter greater than 6mm
also any new mole or old that starts to itch, bleed or ulcerate should be of concern. Another rule is the ugly duckling rule. Which refers to a mole that looks distantly different from the others on your body. ...Read more
Unusual, but: Without knowing many more details it's impossible to guess - bt strange single cases do occur. Each person must deal w/ such a Dx in their best way and with the support of good doctors if possible. ...Read more
Is adoptive cell therapy successful against melanoma? Is it a fully approved treatment yet? Thanks
Usually surgery: Assuming that the melanoma has not spread to other organs, the first treatment is to surgically remove the affected skin with a rim of normal skin. Then, certain patients will also need to have an operation to remove 1 or more lymph nodes depending on the spread. In select cases, melanoma that has spread to other organs is surgically removed. Other patients will need chemotherapy and radiation. ...Read more
Melanoma treatment: The options would include- standard of care treatment vs clinical trials. Standard of care will include: ipilimumab (yervoy) vs vemurafenib (zelboraf) if there is mutated b-raf receptor on melanoma cells vs il-2 for a very limited type of patients vs palliative care (hospice). See more info at www.Cancer.Gov and/or www. Nccn. Com. Discuss with you oncologist the best option for you. ...Read more
Is the cancer likely to recur following treatment? What steps can I take to reduce the risk of additional new melanomas?
Frequent skin checks: Indeed having a personal history of melanoma increases your risk of developing a second melanoma. Statistics have shown at least nine times higher risk than the general population, approximately 11% will develop a second melanoma in 5 years. The 2nd tends to be at an earlier stage likely because of close observation, again highlighting the importance of frequent routine skin checks. ...Read more
No best treatment: Vaginal melanoma is considered mucosal disease and this type tends to spread via the blood to other organs in the body more readily. There is no known best treatment for stage iic. However, based on a recent study, chemotherapy with Cisplatin and temodar (temozolomide) every 3 weeks for 6 cycles are reasonable. However, enrolling in a clinical trial if available is the best option. ...Read more
My father is ostensibly inflicted to melanoma. Could you give me an idea of the best treatment centers for melanoma in the world?
Several: Some of the best melanoma places are the national cancer institute (bethesda, md), md anderson cancer center (houston, tx), memorial sloan kettering cancer center (ny, ny), moffit cancer center (tampa, fl). In ohio, you are probably closer to ohio state university or cleveland clinic. However, these 2 programs are good but not well known for melanoma. ...Read more
Where are we on treatment for skin cancer? Is their a higher percentage for living with having late stage melanoma or other skin cancers?
Depends: It depends on how many metastatic tumors are present, if they can be removed with an operation (ask your surgeon), and what kind of chemotherapy you are eligible for based on the genetic analysis of your melanoma tumor. Generally metastatic melanoma has a very limited survival, but within the last 2 years or so there are at least 2 very promising drugs that have improved this somewhat. ...Read more
Radiation or surgery: Eye melanoma, or ocular melanoma is treated by either removal of the entire eye, or by radiation to the eye. It really depends on the extent of the melanoma. This type of melanoma frequently spreads to the liver, so a ct or MRI of the liver should be obtained. I recommend seeing someone who specializes in this type of cancer due to its relative rarity and severity. ...Read more
Many: The treatment for melanoma involves removing the primary site with a margin depending on the depth of the melanoma. In addition for high risk lesion a sentinel lymph node biopsy is performed. If these lymph node contains melanoma the remainder of the lymph nodes are removed from that basin. Treatment for distant disease can involve surgery, chemotherapy and or immunotherapy. ...Read more
How long can you live with stage 4 metastatic melanoma with mets spread into the brain. What kind of treatment is best?
Radiation +/- surg: If there is only one or two brain metastasis it may be treated with surgery + radiation therapy. More than that number of brain mets usually treated with radiation alone. Disease in body may respond to targeted therapy (e.g. Zelboraf + Mekinist). Yervoy has also helped many. Prognosis depends on a large number of factors which I cannot assess. ...Read more
Choroidal melanoma (1994). No issues since treatment til now. U/s shows 2 spots liver (8.2cm/2.1cm), waiting on mri. If cancer would this likely be considered metastasized from original cancer?
It depends...: If the lesion is suspicious for malignancy by mri, your doctor most likely will schedule a biopsy. The pathologist who reads the biopsy will decide the cell type that is there. If the cell type is melanoma, then it will be considered a metastasis. Many other different cell types can be seen in liver biopsies. If it is a new cell type (carcinoma, lymphoma, or sarcoma), it would be a new cancer. ...Read more
74 year old father has melanoma, congestive heart failure and copd. What are the best forms of treatment?
Melanoma treatment: Surgical treatment is the best. Find a surgical oncologist, dermatologist or a plastic surgeon that can evaluate this asap. ...Read more
My gran had her eye removed due to ocular melanoma 3 years ago. Now metastatic liver cancer, no treatment. No other info given. Life expectancy?
Ask her to ask dr.: Liver metastases from any cancer is not a good sign. However depending on many other factors will determine what her life expectancy is, especially knowing what her constitutional health is, her vitality. So, the best answer would be for her to ask her doctor, or see if she'll give you permission to do so (that must be documented in her chart.) also, make sure that her diet is good, and keep her spirit strong. ...Read more
Not Effective: Graviola or soursop is a fruit grown in rain forests in s.America, africa & se asia. The fruit contains substances known as annonaceous acetogenins which may be able to kill certain cancer cells in a test tube (according to a perdue u study). No studies in humans have been done so there's no evidence that it can work to kill cancer in your body. It can also cause parkinson's like symptoms. ...Read more
No: None of these herbal therapies will cure hcv. I worry about people who have severe liver damage and are not considering curative treatment. Talk to your doctor. ...Read more
Several: Melanoma is almost always treated with surgery first; the amount of surgery depends on the clark level (how deep it is), which is measured in millimeter fractions. A sentinel lymph node (first lymph node to respond) is sometimes removed; chemotherapy and targeted molecular therapies are used in certain circumstances. ...Read more
Adjuncts only: If you ignore surgery for melanoma, you will pay for your mistake with your life. If you are interested in vitamins, botanicals and so forth, remember these are only adjuncts. I am not sure I would accept some of therapies for advanced disease that give only a small survival advantage, but I would not pay a conspiracy or natural-medicine talker for telling me untruths. Be savvy. ...Read more
How long does this person have with stage 4 metastatic melanoma w/ several mets in small bowel and brain? Treatments?
Depends: Traditionally, this would be associated with a short survival. But over the last 3 years, a number of new chemotherapy drugs are available which may significantly extend the quality and duration of patients with metastatic melanoma. Ask your doctor if your melanoma is "BRAF mutant". If so, you are a candidate for a class of drugs. But don't delay, brain mets can be dangerous if not treated. ...Read more
It's eggplant: A pricey concoction of eggplant featured on a far-out television show -- thankfully, promoted primarily for premalignancies that seldom progress. If you have a skin cancer that's a clear and present danger (possible melanoma, ulcerated basal cell carcinoma, rapidly growing anything), get evidence-based treatment instead of an "unproven / spiritual" remedy. It's your life. ...Read more