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Doctor insights on: Graft Versus Host Disease

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Graft (Definition)

Tissues from one location are transferred to another . Also refers to ...Read more


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Looking for top specialist for overlapping graft vs host disease. Husband suffering from steroid refractory skin gvhd. Nothing works. ?

Looking for top specialist for overlapping graft vs host disease. Husband suffering from steroid refractory skin gvhd.  Nothing works. ?

GvHD can be: Challenging. Photophoresis can be a nice adjunct if is available at your treatment center. This is a complex area and details of past therapy needed to give specific thoughts. ...Read more

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Living with Coronary Artery Disease (Checklist)

Take meds as prescribed
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Exercise daily as recommended by your doctor or trainer
daily
Limit meat, dairy, and fats as much as possible
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Eat whole grains only - not white bread
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What are the symptoms of graft-versus-host disease?

What are the symptoms of graft-versus-host disease?

There can be many...: Acute GVHD presents as a skin rash, gut symptoms (nausea or diarrhea) or jaundice. Chronic GVHD commonly causes dry eyes and dry mouth but they can also get quite sore. More serious symptoms of chronic GVHD include sclerosis (scarring or thickening) of the skin, or reduced flexibility due to connective tissue inflammation (fascitis). Pulmonary airflow obstruction may cause shortness of breath. ...Read more

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Can radiology be used to diagnose graft-versus-host disease?

Physical examination: ...and biopsies are the mainstay of diagnosis of graft vs. host disease. Radiology is used mostly to exclude other causes of symptoms, such as an ultrasound of the liver to exclude biliary obstruction, or CT of the chest to exclude infection. ...Read more

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Managing Peripheral Vascular Disease (Checklist)

Try to continue walking
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Make sure risk factors are addressed (blood pressure, cholesterol)
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Inspect your feet daily -- call your MD with any wounds
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What is the difference between graft-versus-host disease and rejection?

GVHD is a reaction..: of engrafted immune cells against the patients healthy tissues. It leads to inflammation and side effects in a variety of tissues. Rejection is the opposite. It is a reaction of the patients immune system against the engrafted cells. In the case of a bone marrow transplant, rejection would cause disappearance of the cells in the marrow and a drop in blood cell production. ...Read more

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Hodgkins lymphoma graft-versus-host disease, what is this?

Cellular immunity: Graft vs. host disease (GVHD) occurs when T lymphocytes from a donor cause inflammation in the normal tissues of a patient. This is a common side effect of allogeneic bone marrow transplants because billions of T cells are infused along with the bone marrow stem cells. It can also occur as a rare, unintended consequence of blood transfusion in Hodgkins patients. ...Read more

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Living with Lyme Disease (Checklist)

Consult an infectious disease doctor.
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Treat symptoms
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See a specialist to treat the area where the symptoms are worst
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What is the medical definition of graft-versus-host disease?

GVHD: occurs when bone marrow stem cells and/or immune cells have been engrafted from one individual into another. Except in identical twins, differences in cellular antigens cause engrafted cells to react against the host tissues and cause an inflammatory injury. Acutely, symptoms may affect the skin, liver, or gut; whereas chronic GVHD may affect the eyes, mouth, fascia, and lungs. ...Read more