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Doctor insights on: Grade 3 Breast Cancer

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What does stage 3 breast cancer mean?

What does stage 3 breast cancer mean?

Advanced: Breast cancer survival is correlated with it's stage, which is predominantly based on the cancer size, it's growth, and lymph node involvement. Stage 3 means that the cancer has grown into the chest wall or skin and/or multiple lymph nodes (including areas outside the armpit) are involved. These are all signs that chemotherapy is needed for potential cure. ...Read more

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Dr. Barry Rosen
4,348 doctors shared insights

Cancer (Definition)

Cancer is a group of diseases that is characterized by uncontrolled cell growth leading to invasion of surrounding tissues that spread to other parts of the body. Cancer can begin anywhere in the body and is usually related to one or more genetic mutations that allow normal cells to become malignant by interfering with internal cellular control mechanisms, such as programmed cell death or by preventing ...Read more


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What causes dcis breast cancer?

What causes dcis breast cancer?

In one word unknown : Ductal carcinoma in situ dcis is simply the sleeping cancer cells inside the breast ducts, like a garden hose loaded with cancer cells safe if they are inside the duct , once they are out side then is invasive cancer, ready to spread, cause is unknown at this time, from genetic mutations, braca i & ii age, hormonal uses.Environment , late age pregnancy life style etc are all attributed. ...Read more

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What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?

What is longterm prognosis for grade 3, stage 1b, triple positive breast cancer, double mastectomy and 6 treatments of TCH with one year of herceptin, (trastuzumab)?

Better now: Exact prognosis is not possible, but your oncologist should discuss your prognosis with based on population statistics, such as Adjuvant! Online, or better still, your Oncotype Dx score based on the gene profile of your cancer. ...Read more

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Survival rate for triple neg receptors for early stage breast cancer after chemo treatment? No lymph nodes involve, stage 1b, grade 2, mastec done

Survival rate for triple neg receptors for early stage breast cancer after chemo treatment?  No lymph nodes involve, stage 1b, grade 2, mastec done

Excellent: According to adjuvant online (www.Adjuvantonline.Com), you have about an 82% 10 yr survival rate based on your specific information provided. This is only an estimate since there are details I do not have such as type of chemotherapy being used. For triple negative breast cancer, these survival rates are quite excellent. ...Read more

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Dear sir, my mother was suffering from brest cancer and her reports are metaplastic carcinoma with spindling &squamous metaplasia grade 3 suggest me?

Dear sir, 
my mother  was suffering from brest cancer and her reports are
metaplastic carcinoma with spindling &squamous metaplasia grade 3  suggest me?

Rare Breast Cancer: Metaplastic breast cancer is quite rare, representing less than 1% of all breast cas. It is so-named based upon its microscopic appearance. While the tendency is for these to be "aggressive" cancers, treatment and survival are based on the cancer stage, just like any other breast cancer. Once your mother recovers from her surgery, she will be referred to a medical oncologist for rx planning. ...Read more

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Is herceptin (trastuzumab) just can heal breast cancer?

Is herceptin (trastuzumab) just can heal breast cancer?

Herceptin (trastuzumab): Herceptin (trastuzumab) is approved for the treatment of early-stage breast cancer that is human epidermal growth factor receptor 2-positive (her2+) and has spread into the lymph nodes, or is her2+ and has not spread into the lymph nodes. If it has not spread into the lymph nodes, the cancer needs to be estrogen receptor/progesterone receptor (er/pr)-negative or have one high risk feature. ...Read more

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Prognosis for 3 pancreatic ampullary cancer tumors. 1 removed with whipple. Chemo 7months helped 1 shrink & 1 disappear. Liver lesions shrank. ?

It depends: Prognosis for Pancreatic Cancer is typically quite poor. But in some patients(5-10%) the tumor can be completely controlled but 90+ percent do tend to get into trouble in one to two years after Surgery. Are you currently free of any visible Cancer in your abdomen? Tell us the details of your recent test results...do they show any tumors or have these been completely controlled??? ...Read more

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What is positive breast cancer survival rate?

What is positive breast cancer survival rate?

?: Positive for what? You mean estrogen receptor positive? Her-2 positive? Lymph node positive??? Can't help you here, friend. Not enough information. ...Read more

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Stage 4 lung cancer with bloody stool?

Stage 4 lung  cancer with bloody  stool?

See your doctor.: Usually for stage IV lung ca, you will get chemotherapy. This can lower resistance to infection, including in the colon which could result in rectal bleeding. Rarely, lung cancer can spread to the bowel causing bleeding. See you m doctor/medical oncologist right away! ...Read more

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Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Can stage 1a endometrial cancer (removed) spread to mediastinal, bilateral hilar and virchow's node w/o infiltrating another organ?

Yes but: It could possibly spread to local lymph node but the chances are very low. The lymph nodes that are in thoracic cavity are even less likely to contain metastatic tumor from a stage 1a endometrial cancer, especially if it's a garden variety low grade lesion. In fact, long term survival is very good, like 95%. The other 5% may represent very high grade tumors. ...Read more

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Do fibrocystic breast changes increase my risk of breast cancer?

Do fibrocystic breast changes increase my risk of breast cancer?

No, fibrocystic breast changes don't increase your risk of breast cancer: Fibrocystic breast changes are common. Women with this noncancerous (benign) condition often have lumpy, nodular breasts and experience breast pain that varies throughout the menstrual cycle. Doctors don't know exactly what causes fibrocystic breast changes, but the condition is likely due to hormone changes during your menstrual cycle that affect breast tissue. Although fibrocystic breast changes don't increase your risk of breast cancer, having fibrocystic breasts may make it more difficult for you to feel a new breast lump or other abnormal change — such as a persistent breast lump that doesn't go away with your next menstrual cycle or thickening or firmness within lumpy breast tissue. It's important to become familiar with how your breasts normally feel so that you'll know when something just isn't right. If you detect something unusual, make an appointment with your doctor to have it evaluated. ...Read more

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Is most breast cancer detected from focal asymmetry?

Is most breast cancer detected from focal asymmetry?

No: Most breast cancer cases are identified on screening mammograms. These breast lesions are usually small and does not cause asymetry. However, when the cancer is more advanced, it can create dimpling in the skin of the breast, or retraction of the nipple, or asymetry of the two breasts, or even swelling or rednessof the breast. One can often detect the breast lump in these cases on self examination. ...Read more

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How does breast feeding lower the risk of breast cancer?

How does breast feeding lower the risk of breast cancer?

Theoretical: No one knows for sure. One theory is that breast feeding makes the cells in the breast do what they are meant to do-- make breast milk. Cancers often arise from cells in our body that haven't matured fully. The hormones your body produces when breast feeding force breast cells to "grow up", making them less likely to become a cancer later on. ...Read more

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My mum has idc breast ca. Primary lump in left breast, axillary nodes, both left&right supraclavicular nodes involvement. Is this stage 4?

My mum has idc breast ca. Primary lump in left breast, axillary nodes, both left&right supraclavicular nodes involvement. Is this stage 4?

Yes/Early stage-4: Spread of tumor into supraclavicular nodes makes it inoperable which males it stage 4(when you add the opposite supracalviculatr nodes. Yet it is early phase of stage -4. Therefore, if treated properly by an experienced breast cancer specialist(medical oncologist), it can be controlled and may even be cured if luck works in her favor. ...Read more

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Is stromal fibrosis commonly mistaken with breast cancer? I was told about radiology pathology discordance

Is stromal fibrosis commonly mistaken with breast cancer? I was told about radiology pathology discordance

Final by pathologist: Yes fibrosis may show in mammography as suspicious but pathologist with trained eye will not mistake it for cancer. Pathologist will give final answer weather is malignant or non malignant fibrosis . Tissue examination is final answer ...Read more

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Stage 3c ovarian cancer in 2011 done several chemo drugs now in liver and have colostomy doc says if no more chemo qual of life 6 mo fair assessment?

Stage 3c ovarian cancer in 2011 done several chemo drugs now in liver and have colostomy doc says if no more chemo qual of life 6 mo fair assessment?

Doc may be right: I can not fully answer your question without knowing which chemotherapy drugs have been used(we have 5-6 good drugs for ovarian cancer). But once the cancer becomes resistant to all drugs then life is short...Usually a matter of months than years. But you can get a second opinion from another oncologist if you want to be absolutely certain. ...Read more

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Breast cancer:mastectomy done;1/12 affedctes nodes; positive hormonal receiver; score0;stage 2; is there a possibility to have a breast cancer again?

Breast cancer:mastectomy done;1/12 affedctes nodes; positive hormonal receiver; score0;stage 2; is there a possibility to have a breast cancer again?

Possible...: It all depends on the pathology report (her2 status..) and treatment provided. No guarantees in life but ! not knowing all the details, she has at least more than 60% chance of cure. Be postive. Encourage her, continue hormonal teatement for at least 5 years. Discuss the case with the oncologist who has all the information and treatment in front of him. Do not be shy. Thanks for asking. ...Read more

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Can a patient stage 1 papillary thyroid cancer with BRAF mutation positive live more than 20 years ( she is 51 years old) ? Thank you very much!

Yes: Papillary thyroid cancer is very common and some people do not even know they have it as small tumors may be found on autopsy when they die of something else. Generally tumors are graded by how ugly they look to the pathologist and how far they've spread. Your tumor has also been molecularly characterized. There are new treatment options available. Please discuss with your oncologist. ...Read more

Dr. Barry Rosen
1,380 doctors shared insights

Breast Cancer (Definition)

Occurs when glandular cells lining the milk ducts and lobules of the human breast begin to grow in an unregulated manner. Often curable if found early and treated effectively with surgery, hormonal therapy, chemotherapy and targeted therapy, or a combination thereof. Early detection before the malignancy becomes large enough to be felt depends on mammography/sonography and MRI imaging of the breast ...Read more


Dr. Mark Hoepfner
1,063 doctors shared insights

Breast Carcinoma (Definition)

Most breast cancers are carcinomas. This is a type of breast cancer. These cancers start in the cells that line organs and tissues. In fact, breast cancers are often a type of carcinoma called adenocarcinoma, which starts in cells that make glands (glandular tissue). Breast adenocarcinomas start in the ducts (the milk ducts) or ...Read more