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Doctor insights on: Goserelin

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Dr. Thomas Fiala
51 Doctors shared insights

Goserelin (Overview)

Goserelin is an anti-prostate cancer agent which is a kind of urology drug.


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What is the action of the drug goserelin?

What is the action of the drug goserelin?

GnRH analog: Goserelin slows the release of gonadotropins, which supresses the function of the ovaries amd testicles, to keep them from producing hormones that might cause a cancer to grow. ...Read more

Dr. Thomas Fiala
51 Doctors shared insights

Goserelin (Overview)

Goserelin is an anti-prostate cancer agent which is a kind of urology drug.


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I'm 18, my endometriosis reactivated, already had one surgery. One doctor wants to prescribe zoladex (goserelin) the other surgery. What should I choose?

I'm 18, my endometriosis reactivated, already had one surgery. One doctor wants to prescribe zoladex (goserelin) the other surgery. What should I choose?

Surgery: Endometriosis is a surgically treated disease. However the correct surgery is crucial. Excision of endo and not cautery or laser is the correct approach. Also important to rule out other causes of pain since endo is often not the direct cause of a woman's pain. You need to see someone who is highly experienced in endometriosis and pelvic pain. Good luck. ...Read more

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Is zoladex (goserelin) effective for breast cancer?

Is zoladex (goserelin) effective for breast cancer?

Depends: Your physician may offer this as one of a variety of possible hormonal manipulations if and only if the pathology team says the tumor is hormone-sensitive. When it works, it is often strikingly successful. ...Read more

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How long does it take for zoladex (goserelin) injection to work IV had it 10 days ago and still in pain with cyst on ovaries?

How long does it take for zoladex (goserelin) injection to work IV had it 10 days ago and still in pain with cyst on ovaries?

IV ZOLADEX (goserelin)???: I do not think that zoladex (goserelin) IV is a currently used treatment for a painful ovarian cyst. Without details as to size and an ultrasound exam showing the cyst's characteristics, I cannot recommend treatment. A painful clear ovarian cyst can be aspirated with ultrasound transvaginal guidance and the pain should go away within a few hours, if not sooner. Hope this info helps! ...Read more

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My husband zoladex (goserelin) inj but now doctors advise him to remove testis, is it safe for him in this age and is he cure by this surgery?

My husband zoladex (goserelin) inj but now doctors advise him to remove testis, is it safe for him in this age and is he cure by this surgery?

Safe, not curative: Zoladex (goserelin) is a drug which prevents the testicles from making testosterone, used to treat advanced prostate cancer. Prostate ca cells thrive in the presence of testosterone. Surgical removal of the testicles accomplishes the same purpose. Neither CURES metastatic prostate ca. Recent study suggests that patients with metastatic prostate ca do better with hormonal therapy + drug docetaxel. ...Read more

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Just started a course of zoladex, (goserelin) what is a side effect?

Just started a course of zoladex, (goserelin) what is a side effect?

Ask your doctor: Www. Drugs. Com is a great website to get your question answered thoroughly. Also ask your doctor....Many times the inserts and web info is over the top complete and can be a bit scary. Ask your doc if he/she is having any side effect issues with other patients or what symptoms would be a concern. ...Read more

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Oncologist recommends zoladex (goserelin) to be injected, given the side effects, is it worth it?

Oncologist recommends zoladex (goserelin) to be injected, given the side effects, is it worth it?

Yes: This assumes the reasons for advising the medicine are valid. With that in mind the answer is yes, overwhelmingly. Also, there are no "side effects" to zoladex (goserelin), (goserelin) only "effects". The goal of zoladex (goserelin) is to lower testosterone levels. Low levels result in a predictable set of issues over time. Side effects (unexpected problems) do not happen w/ zoladex (goserelin). Only the expected! ...Read more

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How long does it take for a woman to have her periods back after taking zoladex (goserelin)?

How long does it take for a woman to have her periods back after taking zoladex (goserelin)?

Depends: Zoladex (goserelin) comes in 3.6 & 10.8 mg implants. The lower dose is designed to supress gonadotropin release (medical menopause) for 28 days. The higher dose for approx 3 months. Usually, you'll resume cycles 1 & 3 months respectively although there can be a 2-4 week lag depending on your age, ovulation patterns, and proximity to menopause. Remember it's not birth control and this is needed. ...Read more

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What is the use of zoladex (goserelin)?

What is the use of zoladex (goserelin)?

Hormone regulation: This agent is a gonadatropin releasing hormone agonist. It interferes with feedback loops that control hormone balance, it stops some hormone production.
It is used in breast cancer, prostate cancer, endometriosis and fibroids to name a few. ...Read more

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What is the action of the drug goserelin?

GnRH analog: Goserelin slows the release of gonadotropins, which supresses the function of the ovaries amd testicles, to keep them from producing hormones that might cause a cancer to grow. ...Read more

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What is the mechanism of action of goserelin?

What is the mechanism of action of goserelin?

It and Lupron (leuprolide): Act in a complex hypothalamic/pituitary axis way, to turn of lh that stimulates testis to produce testosterone, which gives libido but also acts as jet fuel to stimulate pros ca growth. Flutamide/bicalutamide block cell receptors to the testosterone stimulation. ...Read more

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Just started a course of zoladex, (goserelin) what is a side effect?

Ask your doctor: Www. Drugs. Com is a great website to get your question answered thoroughly. Also ask your doctor....Many times the inserts and web info is over the top complete and can be a bit scary. Ask your doc if he/she is having any side effect issues with other patients or what symptoms would be a concern. ...Read more

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Can zoladex (goserelin) be used in eighteen year olds with endometriosis? Is it recommended?

Endometriosis?: I didn't find any fda approval of this drug for endometriosis but it is approved for all adults which include 18 yo. ...Read more

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I'm using zoladex (goserelin) 10.8mg, but when I search about zoladex (goserelin) it says "the 10.8-milligram syringe should not be used in  women" why?

I'm using zoladex (goserelin) 10.8mg, but when I search about zoladex (goserelin) it says "the 10.8-milligram syringe should not be used in  women" why?

Clarify dose: Zoladex (goserelin) at that dose is usually used for prostate cancer in men. It can sometimes be used for breast cancer, endometriosis and other gynecologic disorders. Simply confirm with your doctor the dose you are supposed to be taking. ...Read more

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Can I get pregnant on zoladex (goserelin)?

Can I get pregnant on zoladex (goserelin)?

No!: Zoladex (goserelin) is pregnancy category x, which means there is positive evidence of harm to the fetus in women who are taking it. ...Read more

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How soon after comming of zoladex (goserelin) can I concieve?

How soon after comming of zoladex (goserelin) can I concieve?

That depends: Depends on why you were on zoladex, (goserelin) how long on zoladex, (goserelin) and your age. The older you are and the greater the duration of therapy the longer it will take for your menses to resume normally. ...Read more

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How long does it take for a woman to have her periods back after taking zoladex (goserelin)?

Depends: Zoladex (goserelin) comes in 3.6 & 10.8 mg implants. The lower dose is designed to supress gonadotropin release (medical menopause) for 28 days. The higher dose for approx 3 months. Usually, you'll resume cycles 1 & 3 months respectively although there can be a 2-4 week lag depending on your age, ovulation patterns, and proximity to menopause. Remember it's not birth control and this is needed. ...Read more

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I'm in zoladex (goserelin) had my 1st one 28 days ago about to have the 2nd one I have no side affects I'm on this cause I have cysts that bust I'm still in pain?

I'm in zoladex (goserelin) had my 1st one 28 days ago about to have the 2nd one I have no side affects I'm on this cause I have cysts that bust I'm still in pain?

The pain is from: Irritation of the lining of your pelvic and abdominal area. You may take otc nsaids and ask your dr if he would consider prescribing you opioids for severe pain. Bless u! ...Read more

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What effect does zoladex (goserelin) have on thyroid?

What effect does zoladex (goserelin) have on thyroid?

None: That I have seen. It does not impair TSH (thyroid stimulating hormone) only lh/icsh - the provker of the testis to generate testosterone. ...Read more

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What does zoladex (goserelin) do for cancer patients?

What does zoladex (goserelin) do for cancer patients?

Zoladex (goserelin): Zoladex (goserelin) is helpful for treatment of prostate cancer in men and breast cancer in women.

I am sorry if you have one of these conditions and wish you well.

If you are on Zoladex (goserelin) please have your doctor to give you all the information available.

You can also look up Zoladex (goserelin) on the web. ...Read more

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Is 133.5pmol/l for estrogen and 1.31nmol/l for progesterone low or high if I've been on zoladex (goserelin) for 7 mth?

Is 133.5pmol/l for estrogen and 1.31nmol/l for progesterone low or high if I've been on zoladex (goserelin) for 7 mth?

See answer: Depends on the reason you are on Zoladex (goserelin)...If it is Endometriosis, then your pain should have resolved or if you are on it for bleeding then bleeding should have resolved. Bottom line is it shouldn't matter what your Estradiol and Progesterone are, although your ovaries are suppressed by the levels you posted and your medication is working. Hope this helps. ...Read more

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How long does it take for zoladex (goserelin) injection to work IV had it 10 days ago and still in pain with cyst on ovaries?

IV ZOLADEX (goserelin)???: I do not think that zoladex (goserelin) IV is a currently used treatment for a painful ovarian cyst. Without details as to size and an ultrasound exam showing the cyst's characteristics, I cannot recommend treatment. A painful clear ovarian cyst can be aspirated with ultrasound transvaginal guidance and the pain should go away within a few hours, if not sooner. Hope this info helps! ...Read more

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Is there anything I can do to decrease side effects for zoladex (goserelin) or make them more manageable? Add back therapy will be used.

So many SEs: Zoladex (goserelin) is associated with so many potential ses it is difficult to know how to answer this generic question. Who prescribed it for you and why? Please ask them to help you. ...Read more

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I'm worried that I may be pregnant, I had a zoladex (goserelin) injection in november 10, 8mg, but I still haven't started bleeding, could it be possible.

I'm worried that I may be pregnant, I had a zoladex (goserelin) injection in november 10, 8mg, but I still haven't started bleeding, could it be possible.

Take a test: If you're worried that you may be pregnant, take a home pregnancy test. They are fast and effective and accurate and will give you the information that you are seeking. ...Read more

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Have just had my first dose of zoladex (goserelin) to prepare my womb. What could be a side effect?

Have just had my first dose of zoladex (goserelin) to prepare my womb. What could be a side effect?

Many Things: Hot flashes (flushing), dizziness, headache, increased sweating, decreased sexual interest/ability, trouble sleeping, nausea, change in breast size, hair loss, or mental/mood changes (such as depression, mood swings, hallucinations) may occur. Pain, bruising, bleeding, redness, or swelling at the injection site may also occur. Vaginal dryness may also occur. ...Read more

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Just got a shot of zoladex (goserelin) that should last for 3months, when can I have laproscopy to remove fibroids? Thanks

Just got a shot of zoladex (goserelin) that should last for 3months, when can I have laproscopy to remove fibroids? Thanks

Ask your gynecologis: I am sure he/she has given you some instructions. Just follow them. I do not think there is any hard and fast rule here. I even wonder about why she gave you a zoladex (goserelin) shot? ...Read more

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I am suffering of endometriosys for 4 Years now. I heard about the Visanne treatment. I had zoladex (goserelin) after my surgery in 2011 and it didn't work.

I am suffering of endometriosys for 4 Years now. I heard about the Visanne treatment. I had zoladex (goserelin) after my surgery in 2011 and it didn't work.

Not approved: Visanne is still undergoing clinical trials for relief of pain due to endometriosis and has not yet been approved by the FDA. Large trials are on going and have shown some significant benefit. I am not sure about access to it in Italy but it sounds very promising. Hope this helps. ...Read more

Dr. Lawrence Kessler
49 Doctors shared insights

Zoladex (Definition)

Zoladex is an anti-prostate cancer agent which is a ...Read more


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