Doctor insights on:
Goodpasture Syndrome In Children
Kidney and lung: It is a rare autoimmune disorder. Auto-antibodies attack both kidneys and lungs, Early treatment is vital to help prevent long-term kidney failure. Symptoms may be similar to a UTI, as well as coughing up blood. Fatigue from anemia, nausea and vomiting, swelling of hands or feet, blood and protein in urine, hypertension. See https://www.kidney.org/atoz/content/goodpasture ...Read more
Goodpasture's syndrome occurs when the body encounters a foreign antigen which leads to the abnormal creation of self attacking antibodies to the basement membrane of the kidneys and the pulmonary air sacs. The kidney cells underattack lead to microscopic blood in the urine. Antibodies may also attack lung cells causing dry ...Read more
Autoimmune disease: Antibodies float in blood that attack the kidney and lung tissues. These antibodies are made by the persons immune system when it recognizes some tissues as foreign. The end result is kidney failure and lung failure kind of like bad pneumonia with coughing up blood. It is not infectious. Treatment includes immune suppression to stop these antibodies and plasma exchange to remove antibodies. ...Read more
Cytotoxic hypersense: Goodpasture's syndrome occurs when the body encounters a foreign antigen which leads to the abnormal creation of self attacking antibodies to the basement membrane of the kidneys and the pulmonary air sacs. The kidney cells underattack lead to microscopic blood in the urine. Antibodies may also attack lung cells causing dry cough and minor breathlessness. ...Read more
Immunosuppression: Since the condition is produced by an abnormal immune response, the treatment is to reduce production of the antibody that reacts with the basement membrane of glomerulus, the functional unit of the kidney. Corticosteroids and other immunosuppressant medications are used. Plasmapharesis can be done for severe disease (renal failure requiring dialysis or lung hemorrhage) to reduce antibody amount. ...Read more
Depends on the case: Assuming it is cured, recurrence is always possible. Need to be attached to your nephrologist for long years for follow up. However, if not cured you expect dialysis if kidneys fail. Either case you need to keep an eye on lungs, cough and shortness of breath, since disease may affect them too. ...Read more
Glomerulonephritis: Goodpasture's syndrome is a relatively rare cause of glomerulonephritis. It is caused by antibodies produced to the basement membrane in the glomerulus (functional unit of the kidney) and can cause a severe type of inflammation. Although goodpasture's is a type of glomerulonephritis, not all glomerulonephritis is goodpasture's; there are many other causes. ...Read more
Give me a hint. What kind of hassle am I facing if doc suspects goodpasture syndrome? What is required to diagnose?
Blood test & biopsy: There is a blood test for it called anti gbm antibody which is the antibody that attacks glomerular basement membrane gbm causing kidney failure. Kidney biopsy finding the antibody in kidney tissue is diagnostic. Antibodies may invade lungs too. Treatment is steroids and other immunosuppression meds to arrest disease. May well need plasma exchange. If late diagnosis, may require dialysis. ...Read more
Just got home from doctor. She said I have goodpasture syndrome. Looked it up online and now more confused that ever. Can you explain what it means to have it?
Antibodies in blood: Made by your immune system against kidneys and lungs. If not treated is serious. Kidney failure and lung failure could occur. Treatment is with steroids and other immunosuppression meds. Plasma exchange may be needed to lose antibodies. Early on no need for dialysis which is needed if kidney weakness becomes severe. Cause is unknown. ...Read more
Loc, bleeding&collapsing lungs, blood in kidneys, arrythmia, was on a vent, BP sky rocketed, back on vent.Is this SVT or goodpasture?13yrsold.Thoughts?
For an assessment :
of the child's developmental needs & toilet-training readiness, if < 3 yrs. old, call Pam Barton,
Franklin County Help Me Grow Coordinator at (614) 227-9860. If 3-5 yrs. old, call Lynn Brannon, Director of Early Childhood Special Education at (614) 542-4106.
At the same time, call (614) 355-8080 for an evaluation at the Down Syndrome Clinic, Nationwide Children's Hospital, (614) 355-8080. ...Read more
Many issues: This is a descriptive term indicating an infant or child who fails to meet the parameters for age and size and weight and in fact is falling down. This is an index of problems that need explanation. Categories: child abuse, malabsorption, severe infection, chronic illness, cancer, blood dyscrasias, inherited issues. Your pediatrician should be consulted immediately to sort this out. ...Read more
DS Phenotype: flattened face, upward-slanting eyes, skin folds at inner corners of eyes, transverse palmar crease, & more. Many have congenital anomalies of the heart, intestine, skeletal system & other organs, along with hearing loss, vision problems & certain blood & neurological disorders. Intellectual Disability is usually mild-moderate. Guidelines for medical & developmental care are well-established. ...Read more
Yes.: :simply discuss this issue with your ob/gyn specialists to allay your concerns! ...Read more
No: As a phenomenologically defined entity, and considering that no reliable universal genetic marker was identified, it is impossible to predict with any level of certainty as of now. What is possible though is the diagnostic evaluation of a kid already exhibiting behaviors. ...Read more
ACOG charts show the: risk of having a fetus with a Trisomy 21, Down Syndrome, at prenatal diagnosis vs. the risk of having a live-born infant with DS because ~ 25% are lost. If there is no family history or prior infant with DS, at age 42 at delivery,the risk is 1/63; risk at 16 weeks' gestation is 1/50 - 1/55. Risk of any chromosomal disorder at term is 1/42. If 43 at term, DS risk is 1/49; of any trisomy, 1/33. ...Read more
No good data: This is not quite rare, but also not common. It is more often reported in children but can occur at any age. It is not a mental illness, but a physical perceptual distortion and is usually not part of a dangerous condition. It may be associated w/ migraines or tle and a neurologist might help. Try not to worry about 'craziness' - it is not that. Wish i could offer #s, but i can't. ...Read more
Very rare: This syndrome, where objects or the person's own body appear larger or smaller than normal, is very rare. Some sources say only about 300 adults & children in the us have this. Another source said 9% of teens had transient experiences of micropsia. It can be a migraine equivalent, & can also appear in conditions like seizures, CNS infections, brain tumors, drug use, macular degeneration, etc. ...Read more
Infertility: It may be primary or secondary infertiliy ...Read more
Tachybrady syndrome: TachyBrady Syndrome can occur in young children albeit rare. Infants may present with poor feeding or easy fatigability,which may also be evident in toddlers and older children.Laboratory studies include electrolytes, thyroid studies, echocardiogram, holter monitoring in older children, EP studies. Patients with symptoms require pacemakers and avoidance of medications that can exacerbate the prob. ...Read more
Doubt it would Hapn: While females with ds are capable of reproduction( with difficult pregnancies) males with few exceptions are not. For a male to be capable, i would expect him to be a partially affected mosaic ds & fertility would depend on the tissues of his body that has ds info. Having family support thru their lives is a great asset to anyone with ds or any impairment. ...Read more
I need statistics on aspergers syndrome. How many people have it (children, young adults, adults). ?
Not Well Established: The prevalence of Asperger syndrome (as) is not well established. Experts estimate that as many as 1 in 88 children age 8 will have an autism spectrum disorder. No studies have yet been conducted to determine the incidence of Asperger syndrome in adult populations, but studies of children with the disorder suggest that their problems with socialization and communication continue into adulthood. ...Read more