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Doctor insights on: Glynase Prestab Second Generation Sulfonylurea

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Dr. Luis Curet
131 doctors shared insights

Glyburide (Definition)

Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely ...Read more


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Using amaryl (glimepiride) 3 before breakfast. Glocophage500+ glocovans 500?

Using amaryl (glimepiride) 3 before breakfast. Glocophage500+ glocovans 500?

Sulfonylurea.: That seems like a lot of sulfonylurea type medication - Glimepiride and Glyburide. The reason why that's important is that they can cause hypoglycemia (low blood sugar) which can be dangerous. I'd like to see you on more Metformin and less sulfonylurea to reduce your risk of hypoglycemia. ...Read more

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Are Glimepiride & glipizide the same drug?

Are Glimepiride & glipizide the same drug?

No, but same class: Both are 2nd generation sulfonylurea drugs for treatment of Type 2 Diabetes. According to a review by the Utah gov't, they conclude: "Overall ranges of HbA1c reduction seen w/glimepiride, glipizide & glyburide treatment in current literature are similar & choice of antidiabetes therapy should be based on individual patient characteristics, including: efficacy, cost, (see below) ...Read more

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Difference between first and second generation antihistamines? Why are 1st generation considered nonsedating?

Difference between first and second generation antihistamines? Why are 1st generation considered nonsedating?

Sedation: 1st generation are sedating because many people, up to 40%, get sleepy when taking them. 2nd generation antihistamines are chemically modified and are less likely to cause sedation. The generics of the less sedating are cetirizine, fexafenadine, and loratidine. They cause sedation in some people, up to 11%, but much less than the older drugs. ...Read more

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Is the glipizide more effective than glyburide and januvia (sitagliptin)?

Is the glipizide more effective than glyburide and januvia (sitagliptin)?

No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor. ...Read more

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We think we just put novolog in the levemir (insulin detemir) bottle we have no more levemir (insulin detemir).... Is the levemir (insulin detemir) ruined it was 10 units..

We think we just put novolog in the levemir (insulin detemir) bottle we have no more levemir (insulin detemir).... Is the levemir (insulin detemir) ruined it was 10 units..

Novolog is rapid: Acting ; is used to cover sugars that are elevated pre meals, when you mix the two you could get reaction- do not use the mixture you now have. ...Read more

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Today my doctor prescribe a infertility medicns i.E tinidazole , l_methylfolate, chymoral forte, third generation cephalosporin.Is that good medicn?

Today my doctor prescribe a infertility medicns i.E tinidazole , l_methylfolate, chymoral forte, third generation cephalosporin.Is that good  medicn?

Not fertility meds: The medications you are describing are several antibiotics, vitamins and enzymes. None of these are infertility medications. If you are not sure why he/she prescribed them, you should ask your doctor what they are for. ...Read more

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Type II diabetic, blood insulin last test (NOT glucose)=29.5 On lantus (insulin glargine) 62 units, humalog 17 units. Am I still producing endogenous insulin?

Type II diabetic, blood insulin last test (NOT glucose)=29.5 On lantus (insulin glargine) 62 units, humalog 17 units. Am I still producing endogenous insulin?

Need C-peptide test: Since exogenous (injected) insulin will show on a blood test, C-peptide should be measured to assess for endogenous insulin. Proinsulin is made by the pancreas, then cleaved into C-peptide & insulin. Exogenous insulin has no C-peptide. ...Read more

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Whats the difference between a first generation antihistamine like chlorpheniramine and second generation antihistamines like allegra (fexofenadine)?

Whats the difference between a first generation antihistamine like chlorpheniramine and second generation antihistamines like allegra (fexofenadine)?

1st and second: First generation antihistamines are sedating and short acting and have usually other properties such as anticholinergic or drying properties. Second generation antihistamines are long aciting, usually dosed once a day, and are less or non sedating and selective antihistamines with less active properties on other receptors. ...Read more

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Will i ever have a natural erection again? Taking androgen 4 pumps/d. Have dm ii, ex opioid addict, taking suboxone, Effexor 150mg/d, glucovance (glyburide and metformin)

Will i ever have a natural erection again?  Taking androgen 4 pumps/d.  Have dm ii,  ex opioid addict, taking suboxone, Effexor 150mg/d, glucovance (glyburide and metformin)

ED: Very difficult to say , it depends on how well your diabetes is controlled , how long you been on the androgen and it may or may not help. I hope you can to speak with your doctor at length about this. Good luck. ...Read more

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Do depot antipsychotics (prolixin (fluphenazine) injection) have any advantages over oral antipsychotics (oral prolixin) other than medication adherence ?

Do depot antipsychotics (prolixin (fluphenazine) injection) have any advantages over oral antipsychotics (oral prolixin) other than medication adherence ?

Ans: There are some antipsychotic med studies that show greater effectiveness of the long-acting injection med vs oral in severe psychiatric illness, eg, schizophrenia. Studies have also shown in severe psych. illness that relapse and overall hospital days are less with out-patient care utilizing long-acting antipsychotic med injections vs oral form relying on patient reliability. ...Read more

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Saw a research in which lantus (insulin glargine) and metformin combined treatment linked to high death rate.Plz elaborate or correct me .Is taking both together safe ?

Saw a research in which lantus (insulin glargine) and metformin  combined treatment linked to high death rate.Plz elaborate or correct me .Is taking both together safe ?

Diabetes type 2: Both drugs together are safe but you need to work to make sure that the dosing is correct. 1: Check blood sugar before breakfast and again before lunch. 2: Document all food and snacks taken at breakfast and while waiting for lunch. 3: If blood sugars are close to each other (+/- 25) the diet is fine. 4: However, if blood sugars are stable but >150 you should increase bedtime lantus (insulin glargine). ...Read more

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Husband recently started taking humalog (insulin lispro). Is this the best insulin ?

Husband recently started taking humalog (insulin lispro). Is this the best insulin ?

It's really good.: Humalog (insulin lispro) is a brand of rapid-acting Insulin produced by eli lilly & co. Here in the usa. It is given at meals (or in an Insulin pump), to provide quick-onset action to control blood sugars at meals. There are a couple of other brands of rapid-acting Insulin on the market (novolog, apidra), but they all have about the same action. ...Read more

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I was wondering is biphasic isophane insulin, insugen 30/70 chemically the same as mixtard 30hm penfill insulin?

Insulin mixtures: These insulins do not appear to be available in the US. 70/30 mixes are usually a mixture of NPH and regular. NPH is intermediate in duration (peaks about 10 hr, lasts about 24 hr) and regular peaks about 3-4 hr, lasts about 8. It may say on the bottle or package insert what kind of insulin. Look for the words "NPH" and or "regular". ...Read more

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Why second generation histamine h1 antagonist are the drug of choice in treatment of chronic allergy? Explain please!

Why second generation histamine h1 antagonist are the drug of choice in treatment of chronic allergy? Explain please!

Best allergy medicin: Second generation antihistamines generally have fewer side effects (ie. Sedation and dryness), longer durations of action, and little tachyphlaxis (loose effectiveness with use) than older antihistamines. However for chronic nasal allergies, evidence based medicine places topical nasal steroid sprays as first line therapy ahead of antihistamines, oral or topical. ...Read more

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I take background insulin (humulin i) and quick acting ( Novorapid (insulin aspart)). In Phase 1 I would not need to use the Novorapid (insulin aspart) but what about the Humulin i?

I take background insulin (humulin i) and quick acting ( Novorapid (insulin aspart)).  In Phase 1 I would not need to use the Novorapid (insulin aspart) but what about the Humulin i?

Insulin: I assume Humulin N, and novorapid (insulin aspart). Diabetes in its natural course of the disease tends to progress and likely to use more medicine is not unusual. Initially controlled with the intermediate acting Humulin N is no longer enough and body needs more help with meals, so rapid acting novorapid (insulin aspart) is added. It is standard to use long or intermediate acting insulin along with rapid acting insulin. ...Read more

Dr. Lois Freisleben-Cook
24 doctors shared insights

Glynase Prestab (Definition)

Glynase PresTab is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more