Doctor insights on:
Glynase Prestab Medication
Glynase allergy: Allergic too it. See drug insert.Get a more detailed answer ›
Same family: Hi. Glyburide is a second generation sulfonylurea and glimepiride is a 3rd generation. They work at the same receptors on the beta cell (the pancreatic cells that make insulin) and stimulate insulin release. Glimepiride is preferable because of less metabolite build up in kidney disease, but they're VERY similar. I never use them. In my opinion, based on good science, we have much better drugs. ...Read more
Either glyburide or glimepiride can be prescribed for management of diabetes. There may be a cost difference in your favor or you doctor may have a good reason to prescribe one or the other.
More important - you need to take control of your eating habits, your weight (if overweight), and your exercise.
Also please remember to measure your blood sugar regularly. Your doctor will advise you on dose ...Read more
Similar mechanisms: Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release. They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap. ...Read more
No: You should see a doctor asap.Get a more detailed answer ›
Not many: Glyburide is a sulfonourea (it forces your pancreas to produce more insulin). Metformin does three things... It helps your Insulin work better by making the Insulin receptors in the body more sensitive, it slows glucose absorption in the intestine, and slows the production of glucose by the liver. ...Read more
JANUVIA (sitagliptin): Onglyza, byetta, victoza, (liraglutide) etc. Plenty of choices. ...Read more
Diabetes pill.: Diabeta is a brand of the medication glyburide. It is an effective treatment for type 2 diabetes. It is available as generic Glyburide (lower in cost). It may not be the safest of this class, known as sulfonylurea medications, however (concerns about hypoglycemia in patients with kidney disease and heart effects in patients with heart disease). ...Read more
Hypoglycemia: Prolonged hypoglycemia (mild to severe -low blood sugar- noted as tremor, sweating, headache, fatigue, confusion) is the most common/ concerning side effect of glyburide, this is due to its long half- life / active metabolite compared to other 2nd generation sulfonylureas. Minor weight gain seen. Nausea, heartburn (GI) are transient/ dose related. Rash/itching may occur. Liver injury is rare. ...Read more
Varies (1 - 2 hours): Depending on the formulation ingested (micronized (glynase) or conventional Glyburide (diabeta, micronase)) onset of action ranges from about 1 to 2 hours with a maximum reduction of blood sugar seen within 3-4 hours. May last in body for over 18 to 24 hours. Should be taken with breakfast or main meal of the day to help reduce symptoms of low blood sugar (tremors, sweating, irritable, fatigue). ...Read more
In general glyburide and other sulfonamides are well documented to increase risk of MI about 20% - there are safer options.
Invokana is a SGLTP2i- sodium glucose transport protein inhibitor, that results in sugar in the urine. It has actually been shown to protect kidney function over the long term. It also has a diuretic effect so should skip if you are dehdrated from scan or other reason ...Read more
An insulin releaser:
Glyburide (called glibenclamide outside the U.S.) Is a sulfonylurea anti-diabetic agent. It causes the pancreas to release insulin. It can do this even in the absence of food, so can cause the sugar to get too low.
Glyburide can be a problem in the elderly, again because of the risk for low blood sugar.
If you take this medicine, it could be dangerous to skip meals. ...Read more
Many options: When choosing a diet, make sure it's one that you can maintain lifelong so do not do anything drastic. In general, you should eat lots of vegetable and fruits. Non-starchy vegetables are best: spinach, carrots, broccoli or green beans. Eat whole grain foods instead of processed food (whole wheat over white breads) add fish to your meals 2-3 times per week. Dry beans & lentils are good protein... ...Read more
Either wth or after: Just so you don't skip meals to avoid hypoglycemia. ...Read more
Sick and/or low BG: Hi. If you took too much Glucovance, (glyburide and metformin) the most likely outcomes would be GI symptoms (nausea, vomiting, diarrhea, and/or hypoglycemia). ...Read more
Take glucovance WITH meals.
See link below for additional information in the drug
https://www. Drugs. Com/glucovance. Html ...Read more
What med is better for you actos (pioglitazone) or glyburide I am a 65 year old man whom have been taken glyburide and now my dr want's me to take actos (pioglitazone) I have notice that actos (pioglitazone) have been haveing a lot of lawsuirs
There are pros and cons to all meds. Glyburide is a frequent cause of low blood sugar, sometimes life threatening. It tends to cause weight gain also. As a diabetes specialist, I never prescribe glyburide. Actos (pioglitazone) has many benefits despite the lawsuits. Metformin is often stopped when people can still stay on it. The slow release form of metformin is better tolerated from a diarrhea/stomach standpoint. Metformin is very cheap or even free in some areas of the country. There are newer excellent agents that do not cause low sugar and some can be helpful for weight loss. Insulin is sometimes the best approach and if used right, safer than glyburide.
See the links below. ...Read more
Glucovance (glyburide and metformin): Hi. Glucovance (glyburide and metformin) (metformin + glyburide combination) is not one of my preferred type 2 drugs. But it's inexpensive and will help for awhile before losing effective. Metformin side effects (assuming normal kidney function) are GI (things like nausea, diarrhea). Glyburide side effect is low but real risk of hypoglycemia. If you have decent insurance, there are better type 2 drugs out there. Good luck! ...Read more
What do you advise if I'm using glucovance (glyburide and metformin) is there any problem if I take it along with food?
It's fine: Hi. Yes, it's fine to take Glucovance (glyburide and metformin) with food. ...Read more
What do you advise if I'm using glucovance, (glyburide and metformin) is there any problem if I take it along with food?
In fact: You probably want to take this medication with food. It's a combination of metformin and glyburide. While the metformin isn't likely going to lead to low blood sugars (hypoglycemia) even when taken without food. It's possible that the glyburide could lead to hypoglycemia if you are not eating. ...Read more