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Doctor insights on: Glynase Prestab

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Dr. Darrin Cunningham
24 Doctors shared insights

Glynase Prestab (Overview)

Glynase PresTab is a second generation sulfonylurea which is a kind of diabetes-related drug (nutritional or metabolic agent).


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How long does it take for glyburide to become effective?

How long does it take for glyburide to become effective?

Varies (1 - 2 hours): Depending on the formulation ingested (micronized (glynase) or conventional Glyburide (diabeta, micronase)) onset of action ranges from about 1 to 2 hours with a maximum reduction of blood sugar seen within 3-4 hours. May last in body for over 18 to 24 hours. Should be taken with breakfast or main meal of the day to help reduce symptoms of low blood sugar (tremors, sweating, irritable, fatigue). ...Read more

Dr. Darrin Cunningham
24 Doctors shared insights

Glynase Prestab (Overview)

Glynase PresTab is a second generation sulfonylurea which is a kind of diabetes-related drug (nutritional or metabolic agent).


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Please describe the medication: glyburide?

Please describe the medication: glyburide?

Diabetes medication: Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs. ...Read more

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Is glyburide safe for women who are pregnant or breastfeeding?

Is glyburide safe for women who are pregnant or breastfeeding?

Yes: Glyburide is sometimes used by some physicians during pregnancy for diabetes but this is not the most standard treatment. Most diabetics requiring medication will be changed to Insulin to control blood sugar during pregnancy. ...Read more

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Are there long term effects of diabetes medication (glyburide, metformin)?

Are there long term effects of diabetes medication (glyburide, metformin)?

Not many: Glyburide is a sulfonourea (it forces your pancreas to produce more insulin). Metformin does three things... It helps your Insulin work better by making the Insulin receptors in the body more sensitive, it slows glucose absorption in the intestine, and slows the production of glucose by the liver. ...Read more

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I am a diabetic, my toes are numb sometimes how much trouble am I in without insurance no meds for a year, byetta and glyburide is what I use to take, I have lost 51 lbs still weigh 315#, 6'4 male, 52 years old

I am a diabetic, my toes are numb sometimes how much trouble am I in without insurance no meds for a year, byetta and glyburide is what I use to take, I have lost 51 lbs still weigh 315#, 6'4 male, 52 years old

Urgent: It is urgent that you seek medical attention right away. Being diabetic without your medication is very dangerous and you are leaving yourself open to many serious possibilities. ...Read more

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What is diabeta (glyburide)?

What is diabeta (glyburide)?

Diabetes pill.: Diabeta is a brand of the medication glyburide. It is an effective treatment for type 2 diabetes. It is available as generic Glyburide (lower in cost). It may not be the safest of this class, known as sulfonylurea medications, however (concerns about hypoglycemia in patients with kidney disease and heart effects in patients with heart disease). ...Read more

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Micronase (glyburide) --how is it used?

Type 2 diabetes: This is an older sulfoaurea medication used for type 2 diabetes. ...Read more

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Please describe the medication: glyburide?

Diabetes medication: Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely related to sulfa drugs. ...Read more

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What are potential problems with glyburide?

What are potential problems with glyburide?

Hypoglycemia: Prolonged hypoglycemia (mild to severe -low blood sugar- noted as tremor, sweating, headache, fatigue, confusion) is the most common/ concerning side effect of glyburide, this is due to its long half- life / active metabolite compared to other 2nd generation sulfonylureas. Minor weight gain seen. Nausea, heartburn (GI) are transient/ dose related. Rash/itching may occur. Liver injury is rare. ...Read more

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What are effects of the medication diabeta (glyburide)?

What are effects of the medication diabeta (glyburide)?

DIABETA-GLYBURIDE: Diabeta (glyburide) is a Glyburide generic name, it is used to treat type 2 diabetes along with diet and exercise. It brings the blood sugar down and can sometime cause hypoglycemia. If you skip a meal, exercise too long, drink alcohol, or are under stress. ...Read more

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How long does it take for glyburide to become effective?

Varies (1 - 2 hours): Depending on the formulation ingested (micronized (glynase) or conventional Glyburide (diabeta, micronase)) onset of action ranges from about 1 to 2 hours with a maximum reduction of blood sugar seen within 3-4 hours. May last in body for over 18 to 24 hours. Should be taken with breakfast or main meal of the day to help reduce symptoms of low blood sugar (tremors, sweating, irritable, fatigue). ...Read more

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My grandfather has been prescribed diabeta (glyburide)? Anything to know?

My grandfather has been prescribed diabeta (glyburide)? Anything to know?

DIABETA-GLYBURIDE: Diabeta (glyburide) is a Glyburide generic name, it is used to treat type 2 diabetes along with diet and exercise. It brings the blood sugar down and can sometime cause hypoglycemia. If you skip a meal, exercise too long, drink alcohol, or are under stress. ...Read more

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What would happen if I took too much glucovance (glyburide and metformin)?

What would happen if I took too much glucovance (glyburide and metformin)?

Sick and/or low BG: Hi. If you took too much Glucovance, (glyburide and metformin) the most likely outcomes would be GI symptoms (nausea, vomiting, diarrhea, and/or hypoglycemia). ...Read more

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Can I take my Invokana and Glyburide after my scan?

Can I take my Invokana and Glyburide after my scan?

Probably: B"sd
In general glyburide and other sulfonamides are well documented to increase risk of MI about 20% - there are safer options.
Invokana is a SGLTP2i- sodium glucose transport protein inhibitor, that results in sugar in the urine. It has actually been shown to protect kidney function over the long term. It also has a diuretic effect so should skip if you are dehdrated from scan or other reason ...Read more

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What is glyburide? I'm taking it twice in the morning for my diabetes

What is glyburide? I'm taking it twice in the morning for my diabetes

An insulin releaser: Glyburide (called glibenclamide outside the U.S.) Is a sulfonylurea anti-diabetic agent. It causes the pancreas to release insulin. It can do this even in the absence of food, so can cause the sugar to get too low.

Glyburide can be a problem in the elderly, again because of the risk for low blood sugar.

If you take this medicine, it could be dangerous to skip meals. ...Read more

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I have recently gotten diabeta (glyburide) and what are some good food choices?

I have recently gotten diabeta (glyburide) and what are some good food choices?

Many options: When choosing a diet, make sure it's one that you can maintain lifelong so do not do anything drastic. In general, you should eat lots of vegetable and fruits. Non-starchy vegetables are best: spinach, carrots, broccoli or green beans. Eat whole grain foods instead of processed food (whole wheat over white breads) add fish to your meals 2-3 times per week. Dry beans & lentils are good protein... ...Read more

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What other drugs are aviable to use with glyburide besides metformin?

JANUVIA (sitagliptin): Onglyza, byetta, victoza, (liraglutide) etc. Plenty of choices. ...Read more

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What difference is there between glyburide and glimepiride medications?

What difference is there between glyburide and glimepiride medications?

Same family: Hi. Glyburide is a second generation sulfonylurea and glimepiride is a 3rd generation. They work at the same receptors on the beta cell (the pancreatic cells that make insulin) and stimulate insulin release. Glimepiride is preferable because of less metabolite build up in kidney disease, but they're VERY similar. I never use them. In my opinion, based on good science, we have much better drugs. ...Read more

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What difference is there between glyburide and glimepiride medications?

What difference is there between glyburide and glimepiride medications?

Diabetes: Either glyburide or glimepiride can be prescribed for management of diabetes. There may be a cost difference in your favor or you doctor may have a good reason to prescribe one or the other.
More important - you need to take control of your eating habits, your weight (if overweight), and your exercise.
Also please remember to measure your blood sugar regularly. Your doctor will advise you on dose ...Read more

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Gf is prescribed micronase (glyburide) in am; is that before or after breakfast?

Either wth or after: Just so you don't skip meals to avoid hypoglycemia. ...Read more

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Please explain what are the differences between glyburide and glimepiride medications?

Please explain what are the differences between glyburide and glimepiride medications?

Similar mechanisms: Hi. Glyburide & glimepiride (& glipizide & others in the sulfonylurea class, for that matter) all work by the same mechanism to stimulate endogenous insulin release. They differ in duration of action, metabolites, accumulation in kidney disease, etc. They're archaic drugs that I never use anymore. There are much better type 2 drugs out there. Their one benefit - they're cheap. ...Read more

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Is the glipizide more effective than glyburide and januvia (sitagliptin)?

No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor. ...Read more

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What med is better for you actos (pioglitazone) or glyburide I am a 65 year old man whom have been taken glyburide and now my dr want's me to take actos (pioglitazone) I have notice that actos (pioglitazone) have been haveing a lot of lawsuirs

What med is better for you actos (pioglitazone) or glyburide I am a 65 year old man whom have been taken glyburide and now my dr want's me to take actos (pioglitazone) I have notice that actos (pioglitazone) have been haveing a lot of lawsuirs

There: There are pros and cons to all meds. Glyburide is a frequent cause of low blood sugar, sometimes life threatening. It tends to cause weight gain also. As a diabetes specialist, I never prescribe glyburide. Actos (pioglitazone) has many benefits despite the lawsuits. Metformin is often stopped when people can still stay on it. The slow release form of metformin is better tolerated from a diarrhea/stomach standpoint. Metformin is very cheap or even free in some areas of the country. There are newer excellent agents that do not cause low sugar and some can be helpful for weight loss. Insulin is sometimes the best approach and if used right, safer than glyburide.
See the links below. ...Read more

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Is glyburide safe for women who are pregnant or breastfeeding?

Yes: Glyburide is sometimes used by some physicians during pregnancy for diabetes but this is not the most standard treatment. Most diabetics requiring medication will be changed to Insulin to control blood sugar during pregnancy. ...Read more

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Should glucovance (glyburide and metformin) 500 mg be taken before or after meals?

WITH meals: Take glucovance WITH meals.

See link below for additional information in the drug
https://www. Drugs. Com/glucovance. Html ...Read more

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Do you know if there are side effects from taking glucovance (glyburide and metformin)?

Glucovance (glyburide and metformin): Hi. Glucovance (glyburide and metformin) (metformin + glyburide combination) is not one of my preferred type 2 drugs. But it's inexpensive and will help for awhile before losing effective. Metformin side effects (assuming normal kidney function) are GI (things like nausea, diarrhea). Glyburide side effect is low but real risk of hypoglycemia. If you have decent insurance, there are better type 2 drugs out there. Good luck! ...Read more

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What do you advise if I'm using glucovance, (glyburide and metformin) is there any problem if I take it along with food?

What do you advise if I'm using glucovance, (glyburide and metformin) is there any problem if I take it along with food?

In fact: You probably want to take this medication with food. It's a combination of metformin and glyburide. While the metformin isn't likely going to lead to low blood sugars (hypoglycemia) even when taken without food. It's possible that the glyburide could lead to hypoglycemia if you are not eating. ...Read more

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What do you advise if I'm using glucovance (glyburide and metformin) for diabetes is there any problem if I take it along with food?

What do you advise if I'm using glucovance (glyburide and metformin) for diabetes is there any problem if I take it along with food?

No: It's actually recommended to take glucovance (glyburide and metformin) with food. This will prevent hypoglycemia and make the metformin component of the drug more tolerable. ...Read more

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My doc's been trying diff. Mg's of sugar pills, I'm on glyburide 10mg bid and #'s not getting better. #'s bet. 160-250. Should I just be on insulin?

Depends: It depends on if you're a type 1 or 2 and your a1c. Sometimes you need 2 or more drugs to get things under control. Glyburide is not a good drug. If you need to use a drug in this class, I would use Glimepiride instead. Metformin is the drug of choice for treatment of type 2 dm. Please discuss with your doctor. ...Read more

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I am 34 y old man I am suger patient last 6yers, I am taking medicine glucovance (glyburide and metformin) 500/5 in a day 1/1/2. Please let's me know, any side effect?

Glucovance (glyburide and metformin): Glucovance (glyburide and metformin) = Glyburide + metformin. Check out http://www. Drugs. Com/glucovance. Html for information re this drug. Need to monitor kidney function if you're taking metformin. Don't skip any meals because Glyburide can cause hypoglycemia (excessively low sugar) which isn't an issue w/metformin by itself. Be sure to monitor a1c every 3-6mo. See ophthalmologist annually. Check feet daily. ...Read more

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I want to know why you can't take glyburide after a CT scan?

I want to know why you can't take glyburide after a CT scan?

Metformin: If you are taking only Glyburide there should be no problem taking it after the ct. The issue revolves around metformin/glyburide combination drugs since the metformin component increases the risk of developing lactic acidosis, a serious metabolic condition, when take with the IV contrast material.. ...Read more

Dr. Luis Curet
131 Doctors shared insights

Glyburide (Definition)

Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely ...Read more


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