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Doctor insights on: Glyburide And Metformin

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Are special advantages of janumet (sitagliptin and metformin) over metformin?

Are special advantages of janumet (sitagliptin and metformin) over metformin?

GLP -1 analogues: Janumex is a pill which combines januvia (sitagliptin) in addition to metformin so it combines two different ways glucose is lowered in your blood stream januvia (sitagliptin) lowers glucagon after eating and decreases blood glucose after eating and complements metformin which lowers mainly fastingsome adverse publicity around januvia (sitagliptin) related to pancreatitis the jury is still out. ...Read more

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Dr. David Sneid
1,049 doctors shared insights

Metformin (Definition)

That reduces liver production of glucose- other benefits: can't cause low blood sugar when used alone, likely cariovascular benefit, may reduce complications of diabetes, may reduce cancer risk ...Read more


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How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

How do glimepiride, metformine, lantus (insulin glargine) and byetta work together?

Diabetes: The four medications work in 4 different mechanisms with the end goal of keeping blood sugar under control. Would suggest taking Glimepiride in mornings, metformin & Byetta before meals & Lantus (insulin glargine) at bedtime. Goal fasting blood sugar of 100 & hba1c of 6.5 good luck. ...Read more

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How janumet (sitagliptin and metformin) is beneficial compared to just metformin?

Janumet (sitagliptin and metformin) is : Metformin plus what is called a dpp-4 inhibitor, which stimulates Insulin release, blocks hormones that raise your sugar and makes the combo w/metformin more potent at lowering your blood sugar. ...Read more

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Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Is janumet (sitagliptin and metformin) more effective compared to just metformin?

Yes: Hi. Metformin and sitagliptin work via different mechanisms, and together are synergistic. So yes, more effective than one drug alone. Note even the combination may not be adequate for achieving tight control. Your doctor will follow your A1c response, and if it's in the mid-low 6's, you're good to go. A nice thing is Janumet (sitagliptin and metformin) by itself cannot cause hypoglycemia. Good luck! ...Read more

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Can i continue amaryl (glimepiride) 2mg and discontinue janumet ?

Can i continue amaryl (glimepiride) 2mg and discontinue janumet
?

Why?: There might be more details in the question that i'm missing but don't stop any meds without talking to your prescribing physician first. ...Read more

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Is the glipizide more effective than glyburide and januvia (sitagliptin)?

Is the glipizide more effective than glyburide and januvia (sitagliptin)?

No: Depending on how high your initial sugar levels are all 3 will lower the a1c about 0.3-1.0%. Glyburide is a poor choice for people with kidney problems and januvia (sitagliptin) is expensive. Most guidelines suggest beginning with metformin. Talk to your doctor. ...Read more

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What are the side effects of taking glucophage (metformin) tab and daonil for diabetes control?

What are the side effects of taking glucophage (metformin) tab and daonil for diabetes control?

Not many: Hi. Metformin can cause GI upset fairly common, but better if dose is slowly titrated upward); if used in kidney disease patients, it can cause a serious illness, lactic acidosis (very rare). Glibenclamide/glyburide can cause low blood sugar (rare) or rash (also rare); it is a very archaic diabetes drug. Good luck! ...Read more

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Amaryl (glimepiride) to control blood sugars?

Amaryl (glimepiride) to control blood sugars?

For type 2 diabetes: Amaryl (glimepiride) is an oral medication which helps the pancreas make more Insulin in patients with type 2 diabetes. ...Read more

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Type2 diabetic. Metformin 500mg 2xday but stomach issues. Will victoza (liraglutide) lower a1c and help weight loss along as monotherapy so i can stop metformin?

Type2 diabetic.   Metformin 500mg 2xday but stomach issues.  Will victoza (liraglutide) lower a1c and help weight loss along as monotherapy so i can stop metformin?

Talk to doctor: Management of diabetes is not a do it yourself issue. It would be prudent to discuss these issues with your doctor and not go around changing your medication on your own. ...Read more

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Any complications from taking janumet (sitagliptin and metformin) for type 2 diabetes?

Minor: You can have GI problems from the metformin, and uncommon other problems from either component of the drug -- just like any and all medicine. Otherwise, it's one of the safest medications ever. ...Read more

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Can you take actos (pioglitazone) and amaryl together?

Can you take actos (pioglitazone) and amaryl together?

Amaryl (glimepiride) and actose: Yes you can and this combination has been used in type 2 diabetes. ...Read more

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Is janumet (sitagliptin and metformin) safe to take? I am type 2 diabetic.

Is janumet (sitagliptin and metformin) safe to take?  I am type 2 diabetic.

Generally yes: Janumet (sitagliptin and metformin) is safe as long as you tolerate metformin without problem and have relatively normal kidney function. Your doctor can help you out with these questions and check your lab to see if you're appropriate. ...Read more

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As lowering the sugar i take metformin 500mg

As lowering the sugar i take metformin 500mg

I : I wish i could help, but your question is not complete. Metformin is an oral agent used to control blood sugar in patients whose sugar balance is disturbed but who do not need insulin. ...Read more

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Hello. Is omega XL safe for diabetics taking insulin metformin glipizide Lipitor (atorvastatin) diazid tricor & bp meds, spiriva advair. ?

Hello. Is omega XL safe for diabetics taking insulin metformin glipizide Lipitor (atorvastatin) diazid tricor & bp meds, spiriva  advair. ?

Exercise caution: you are already on multiple medications, some possibly interact together, you don't want to add more unless really needed, even if it is a supplement, fatty acids in omega fish oil might increase lipids in your system, this is not against any drug but rather for your own safety, please revise all your meds with your doctor on regular basis, good luck ...Read more

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Does novorapid and lantus (insulin glargine) work well for diabetes?

Does novorapid and lantus (insulin glargine) work well for diabetes?

Yes: These are two very good Insulin frequently used in the treatment of both type of diabetes. ...Read more

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Can i continue with amaryl 2 mg and discontinue janumet (sitagliptin and metformin) as it gives me stomach discomfort?

Can i continue with amaryl 2 mg and discontinue janumet (sitagliptin and metformin) as it gives me stomach discomfort?

Talk to your doctor: Tell your doctor about the stomach discomfort so that he/she can evaluate and prescribe a different regimen. You might want to break the janumet into januvia (sitagliptin) and metformin and eliminate one drug at a time to see which one is causing the discomfort. In any case. Don't stop meds without letting your doctor know about it. ...Read more

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I have puffy ankles and rapid weight gain with Novolin (insulin) H, while taking Metformin. Is it possible to take only Novolin (insulin) R with the Metformin?

I have puffy ankles and rapid weight gain with Novolin (insulin) H, while taking Metformin.  Is it possible to take only Novolin (insulin) R with the Metformin?

Weigh gain: Hi. Yes, it's certainly possible to use just R with metformin. Insulin is strongly associated with weight gain. Type 2 drugs that are NOT associated with weight gain, and are actually associated with weight loss include the GLP-1 agonist drugs (Victoza (liraglutide) & Byetta) and the SGLT-2 inhibitor drugs (Invokana & Farxiga). Metformin & the DPP-4 inhibitors are weight neutral. Good luck! ...Read more

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Dr. Luis Curet
131 doctors shared insights

Glyburide (Definition)

Used with diet and exercise to help control blood sugar in patients with type 2 diabetes. It is an antidiabetic drug in a class of medications known as sulfonylureas, closely ...Read more


Dr. Andrew Berry
24 doctors shared insights

Glynase Prestab (Definition)

Glynase PresTab is a second generation sulfonylurea which is a kind of diabetes-related drug ...Read more