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Doctor insights on: Gleevec

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Dr. Lonnie Smith
34 doctors shared insights

Gleevec (Overview)

Gleevec is an aklylating agent which is a kind of cancer drug.


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Can gleevec (imatinib) cure retinoblastoma?

Can gleevec (imatinib) cure retinoblastoma?

No data yet...: Gleevec (imatinib) inhibits a number of tyrosine kinases in cells (c-kit, pdgfralpha, c-abl) . There is very recent data that Gleevec (imatinib) may have activity in retinoblastoma, but these experiments where done on isolated retinoblastoma cells grown in culture. There are no clinical trials showing that Gleevec (imatinib) can treat retinoblastoma. Future clinical trials may be planned to address this question. ...Read more

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Dr. Lonnie Smith
34 doctors shared insights

Gleevec (Overview)

Gleevec is an aklylating agent which is a kind of cancer drug.


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Whats imatinib mesylate?

Whats imatinib mesylate?

Enzyme inhibitor: This drug, gleevec, (imatinib) is used to treat chronic myeloid leukemia and gastro-intestinal stromal tumors. It acts by inhibiting and enzyme produced by tumor cells. ...Read more

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What is better to treat lymphocytic leukemia gleevec (imatinib) or bone marrow transplant?

What is better to treat lymphocytic leukemia gleevec (imatinib) or bone marrow transplant?

Type of Leukemia?: More details are needed to answer this question, specifically what is the leukemia type? Is it acute lymphoblastic leukemia, chronic lymphocytic leukemia, or are you referring to chronic myeloid leukemia? Please ask this question again with the additional information so it can be answered. ...Read more

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Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Peripheral t-cell lymphoma cure: chop induction+ifosfamide/mtx + autologous transplant or romidepsim+brenduximab?

Complex problem: Cannot comment with 2 lines of information. Need the entire clinical context. If you seek more detailed information get a formal second opinion. ...Read more

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Is nexavar (sorafenib) prescribed for hepatocellular carcinoma?

Is nexavar (sorafenib) prescribed for hepatocellular carcinoma?

Yes, for Stage 4: Nexavar, or sorafenib, is used to treat advanced, unresectable hepatocellular carcinoma. It is also used to treat patients with advanced kidney cancer. This drug is a multikinase inhibitor and works by decreasing tumor growth and replication, by inhibiting the formation of blood vessels that tumors rely on to get nourishment. This is not a curative treatment, prolonging survival on average 7 mo. ...Read more

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Anyone know of effects with gleevec (imatinib)?

Gleevec (imatinib) info: Open this link: http://www.Nlm.Nih.Gov/medlineplus/druginfo/meds/a606018.Html.

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Are the cancer drugs, gefitinib and tarceva (erlotinib) available?

Are the cancer drugs, gefitinib and tarceva (erlotinib) available?

While gefitinib was: Developed first, it is hard to find in america (iressa (gefitinib)). Erlotinib (tarceva) has more side effects, but a trial showed a survival advantage. Probably more related to the characteristics of the study participants than the drug. These are small molecule, tyrosine kinase inhibitors in the erb family of receptors. Canada and europe has iressa (gefitinib). Erlotinib is in us. ...Read more

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Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Is revlimid (lenalidomide) effective for acute myelogenous leukemia?

Possibly: If the leukemia develops out of a myelodysplasia and has evidence of a 5q-, then possibly. But, the results are mediocre at best. Not curative by any stretch but could possibly slow the leukemia down for a short time. Hope this helps. ...Read more

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Does Taxol (paclitaxel) stabilize microtubules?

Does Taxol (paclitaxel) stabilize microtubules?

Taxol (paclitaxel): Yes. You can read about this "Insights into the mechanism of microtubule stabilization by Taxol" See: http://www.pnas.org/content/103/27/10166.full ...Read more

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Stem cell transplant for ovarian cancer--will it prolong survival rate?

Stem cell transplant for ovarian cancer--will it prolong survival rate?

Yes possible: With out knowing stage and cell type of ovarian cancer , in general high dose chemotherapy with autologous ( patients own ) stem cell transplantation is promising to prolong the life, cure is not near yet, as most of the tumors are drug resistant ( or right drug is not there ) and have residual tumor in the body. ...Read more

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Is matulane (procarbazine) useful to non-hodgkin's lymphomas?

No: Only indication is for hodkin's disease, and even in that condition, where it is used as part of the "mopp" regimen, it has been replaced by other regimens. It may have slight activity in other lymphomas but there are now many other effective chemotherapeutic and biologic choices. ...Read more

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How effectice is Xeloda (capecitabine) for metastatic breast cancer?

How effectice is Xeloda (capecitabine) for metastatic breast cancer?

Quite effective: Xeloda (capecitabine) is quite an effective drug and has been used in metastatic breast cancer. The response will be higher when it is combined with other chemotherapy agent- with additional possible side effects. Discuss further with you oncologist in detail. ...Read more

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Can doxil (liposomal doxorubicin) treat multiple myeloma?

Can doxil (liposomal doxorubicin) treat multiple myeloma?

Yes: Yes, Doxil (liposomal doxorubicin) can be used to treat multiple myeloma. Discuss further in detail with your oncologist -whether the chemotherapy would be appropriate for your case. ...Read more

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How effective is Xeloda (capecitabine) for metastatic breast cancer?

How effective is  Xeloda (capecitabine) for metastatic breast cancer?

It depends: As the first treatment for metastatic breast cancer, Xeloda (capecitabine) works in 40-60% of people treated. If it is the second, third or later treatment after failure of other agents, the effectiveness is much less. ...Read more

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How effective iressa (gefitinib) for lung cancer after chemo?

How effective iressa (gefitinib) for  lung cancer after chemo?

Only if ..: Gefitinib will only work if there is a egfr mutation detected on the cancer. It will not be effective if there is no egfr mutation detected. ...Read more

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Is Xeloda (capecitabine) effective for breast cancer?

Is Xeloda (capecitabine) effective for breast cancer?

Xeloda (capecitabine) for breast ca: Xeloda (capecitabine) also known as Capecitabine is a very effective oral chemotherapy drug used for metastatic or stage 4 breast cancer. It can be used by itself (mono therapy) or as part of combination chemotherapy. Major side effects include diarrhea, hand foot syndrome, nausea and small chance of coronary spasm. It is well tolerated. Patients on Xeloda (capecitabine) need to be followed closely by medical oncologists. ...Read more

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Dr. M. Hytham Beck
29 doctors shared insights

Imatinib Mesylate (Definition)

Imatinib mesylate is a carbapenem which is a kind of anti-bacterial ...Read more