Doctor insights on:
My daughter has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) Any OTC medications she can take instead?
Contact prescriber: Copaxone (glatiramer) is a specific combination of biologic agents used for treating MS (L-alanine, L-Lysine, L-glutamic acid and L-Tyrosine) . Try discussing with her prescribing doctor - there may be a way to get a short supply of her meds at a discounted price for a while. ...Read more
What's the most effective medication for secondary progressive multiple sclerosis? My dr has me on copaxone (glatiramer) for almost a year now and it's not helping
Multiple sclerosis: With the exception of Novantrone (mitoxantrone) and steroids there is no other approved therapy for secondary progressive ms. The new oral therapies and old injectable platform therapies are only effective in relapsing ms (slow down number of relapses over time) not effective in progressive ms. Physical therapy, ampyra, (dalfampridine) muscle relaxer and other medications could be used to improve symptoms of ms. ...Read moreSee 1 more doctor answer
I have started my medication in june (which is an injection of copaxone (glatiramer) everyday) I have yet to get my period?
Unusual reaction: Copaxone (glatiramer) does NOT usually affect hormonal function, and need to have your gynecologist assess this. Sounds like a co-morbidity rather than a direct relationship, but unique reactions can and do occur. If no explanation otherwise, perhaps not a bad idea to try a different disease modifying agent. ...Read more
I have had tingling/numbness in my finger tips since july 13 and i take copaxone (glatiramer). I wanted to know is there a medication to stop numbness?
Need a diagnosis: If the numbness is due to ms, you may be experiencing a relapse, and that could be treated with a steroid or acth. If the numbness is due to a peripheral nerve issue such as carpal tunnel, this could be treated directly. You need to discuss with your doctor and search out the etiology and then address with specific intervention. You see, ms can co-exist with other problems and these need eval. ...Read moreSee 1 more doctor answer
What medications can help the forgetfulness associated with ms. I takw copaxone (glatiramer) daily. No other medicatiins. Lab work chemistries and thyroid are ok?
Side effects: There are side effects related to the treatment of multiple sclerosis, as well as the effects of the disease itself on attention, concentration and memory. In some cases the addition of antidepressants will improve the cognitive effects and the low mood associated with the condition. A consultation with the psychiatrist could be very helpful. ...Read moreSee 1 more doctor answer
What are the side effects for taking oral MS drugs as opposed to copaxone (glatiramer) and all the other injectable drugs.
Complex : All ms drugs have potential side effects, and Copaxone has injection site reactions, lipoatrophy, an occasional chest/flushing reaction, and of course, the need to inject. All three orals are well tolerated in most folks, but tecfidera may cause severe nausea, diarrhea. Better tolerated might be Gilenya (fingolimod) or aubagio. Talk to neurologist about your best approach. ...Read moreSee 1 more doctor answer
I am ending using copaxone (glatiramer) after more than two years. I am going to try bd 12 (not yet available to australians). Should there be a waiting period before starting a new drug?
Variable.: Local injection site pain may last a few minutes, unless the area becomes infected or swollen. Dimpling in the injection site, lipoatrophy, occurs in up to 60% of patients, and may be permanent. Brief injection rxtns associated with chest pain, flushing, sweating, etc, are rare and benign and last about 15 min. Hypertension may occur, and, if so, may be permanent. ...Read more
See answer below: Most common side effects of Copaxone (glatiramer) are injection site reactions with redness or welts that can last a few days. Occasionally, patients will report severe chest pain that occurs once or twice a month and is limited to 3-5 minutes in duration. More rarely, patients will report flushing in the face followed by severe chills and incontinence that can last up to 3 hours. ...Read more
Variable.: Local injection site pain may last a few minutes, unless the area becomes infected or swollen. Dimpling in the injection site, lipoatrophy, occurs in up to 60% of patients, and may be permanent. Brief injection rxtns associated with chest pain, flushing, sweating, etc, are rare and benign and last about 15 min. Hypertension may occur, and, if so, may be permanent. ...Read moreSee 2 more doctor answers
NMO: In the old days, we thought that nmo was a variant of ms. Now we realize that it is very different, although may present the same way. Because it is so rare, there will never be enough people in an fda trial to approve a drug therapy. I have had success with rituxan (rituximab). Two men in this country are the leading experts on the topic, dean wingerchuck at mayo clinic and ben greenberg at utsw. ...Read more
See answer below: Both are used in rrms with similar efficacy levels. Copaxone (glatiramer) does not need blood monitoring and is administered as a subcutaneous sc injection daily. Side effects include injection site reactions. Interferons need lab work monitoring, can be a weekly injection into a muscle (avonex), every other day sc (betaseron) or three times a week sc (rebif). Most commo side effects include flu-like symptoms. ...Read more
VERY DIFFERENT: Entirely different chemical classes, with distinct different mechanisms of action, and outcome data. Both seem safe, Copaxone (glatiramer) tho is injected daily, causes lipoatrophy, hypertension, and injection reactions. Tecfidera may be tough to tolerate due to flushing, nausea, diarrhea, stomach pain. Copaxone (glatiramer) relapse reduction is 29%, but tecfidera, drops 44-52%, oral twice daily, no needles. Talk to doc. ...Read more
Some control: Decrease relapses about 29%, forestalls disability, and may prevent MRI lesions. Works by controlling inflammatory lymphocyte attack on brain and spinal cord. Is a modestly potent medication, and works more effectively in the newer 40 mg TIW formulation. ...Read moreSee 1 more doctor answer
Somewhat: Copaxone is seemingly the most used drug for ms, but likely intermediate in efficacy. We use relapse rate reduction c/w placebo, as one measure, and Copaxone has been shown consistently to have a 29% rrr. This is about the range for betaseron, and rebif. Contrast to tysabri, (natalizumab) about 68%, Gilenya 54%, and a promising drug bg-12, 44-53%. The choice of a med should also consider risk. ...Read more
Variable: Copaxone (glatiramer) is a first line agent which may not be useful for many pts, and may take up to 4-6 months to reach maximal potency in some pts. If relapses continue to occur, and your MRI shows active lesions, other meds may be better choices for you. Discuss thoroughly with your neurologist. ...Read more
What do you suggest if my child has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) what do we do?
In lady patients with ms, should they stop taking copaxone (glatiramer) when trying to get pregnant?
PERTAINENT QUESTION: Likely, Copaxone (glatiramer) safe, as fda considers it a category b drug, but, usually, i suggest holding it for a while before conception, just to be extra cautious. Also, pregancy is clearly protective, and being off the Copaxone (glatiramer) is not risky then. After labor and delivery, i restart within 48 hrs, as we need to prevent post-partum relapses, which can occur about 6-8 weeks after baby arrives. ...Read more
Yes, but see below: Both, especially Copaxone (glatiramer) are quite safe, but require injections, with risk of skin reactions with both, and permanent site dimpling with copaxone (glatiramer). Rebif can cause flu-like rxtns, depression, liver issues, thyroid problems, in addition. Copaxone (glatiramer) may have brief chest pain, breathlessness, and flushing after injection.(hypertension is reported) Copaxone (glatiramer) is safer for pregnancy. ...Read moreSee 2 more doctor answers
Infrequent, but: Injection site reactions can be seen, usually just reddening, but may see more intense local reaction. A less frequent injection reaction involves throat and chest pain, flushing sensation over face and chest, tingling, and generalized malaise lasting several minutes. This is not a heart issue, and turns out to be quite benign but can be very scary. ...Read more
Depends: This medication suppresses your immune system. We don't have any good information on it in pregnancy. It really is a case of discussing with your doctor the risks and benefits. In breastfeeding, we don't have a lot of information but it is a pretty big molecule and probably doesn't end up in breast milk so we feel comfortable with women breastfeeding on this med. ...Read moreSee 1 more doctor answer
Have ms. On Copaxone (glatiramer) but missed a few doses. Worried about my brainstem lesions and if they mean a worsened prognosis or risk of death?
No immediate risk!: Consult your specialist to make sure that your Copaxone (glatiramer) has prevented MS relapse Usually an MRI with and without Gadalinium injection would tell us if the condition is active Although you should take your Copaxone (glatiramer) regularly missing couple of injections is not a big problem but don't miss anymore!! There is NO risk of death ...Read more
Why would my neurologist since 2011, have me on copaxone (glatiramer) injections, telling me I have ms, put in her notes, she does not believe I have ms?
My response: We are not able to mediate doctor- patient communications, and I personally do not have capacity to read minds. Since you are taking an expensive injectable medication, would directly address this with your doctor, and if necessary, get a second opinion. ...Read moreSee 2 more doctor answers
Does copaxone (glatiramer) effect the way tamoxifen works, on tamoxifen since 2010, menstrual cycle stop, started copaxone (glatiramer) in october 13' cycle came 2 weeks after?
Ms - started rebif after a severe allergic reaction to copaxone (glatiramer). Now extremely itchy. Could it be the rebif or the MS itch?
Could be side fx: Rebif and copaxone (glatiramer) are not the same, but your symptom of itching could be caused by your new medicine. If it does not subside soon, say 2-3 days, it may be helpful to make a change, or use some kind of treatment for the possible side effects. ...Read moreSee 2 more doctor answers
If I have a weak immune system due to copaxone, (glatiramer) does that make me more susceptible to cancer?
Probably not: The largest studies of long-term Copaxone (glatiramer) use do not show a significantly increased risk of cancers. However, there is a theoretical risk that decreasing the activity of the immune system could increase the chances of a cancer developing or growing more quickly. These concerns should be discussed with your neurologist so you can weigh this small risk against the benefits of this ms treatment. ...Read moreSee 1 more doctor answer
Taking copaxone (glatiramer) for many years for my MS . I have pain in my right big toe with inflamation . Could my body systems not want me to take it .... Gout?
Need to reassess: At your current age, 77, you may no longer need copaxone, (glatiramer) and if you developed a secondary progressive ms transition, this drug would not be appropriate to handle that either. The pain in your toe could be gout, but other explanations may be considered. Yes, check your uric acid, but also update MRI of brain, and get full neurological re-evaluation. ...Read moreSee 1 more doctor answer
How to stop the MS hug? I take copaxone (glatiramer) and I sometimes can't move my toes for a few min it feels like leg muscle being squeezed
Complexities: The "MS Hug" is an indication of spinal cord involvement, and presence is most often a sign of a relapse, which would need treatment with steroids or ACTHAR. If you have active ongoing new inflammation, recommend switching your medication to a more potent agent. We might best discuss this via a Concierge virtual consult. ...Read more
How do u try to stope getting plaque on your brain when u have MS. Took MRI in JAN. and last wk and I have more plaque. On copaxone (glatiramer)
No major bullet: Unless we fully understand what MS is all about, we can do little to totally control the disease process. ...Read more
I take copaxone (glatiramer) when i take it I have gout pain in big right toe . My neurologist said cut down copaxone (glatiramer) to 3 times a week .Is this ok ?
I have been diagnosed with MS 12 years ago .. I. Take Copaxone (glatiramer) and my MS has not progressed . I have hip flexor rt leg can I do something to GT bett?
I have MS Dx an my neuro is putting me on copaxone (glatiramer). Is the chest pain from copaxone (glatiramer) coming from the heart and is it dangerous? Doesnt seem safe.
Heart is safe: Normally copaxone (glatiramer) does not cause any cardiac problems. Copaxone (glatiramer) is a very safe medicine, one that tends not to cause side effects, but of course there are exceptions. Your symptoms are probably coming from the chest wall, like the muscles. You might also wonder about GERD- since you are taking medicine for GERD. That also causes chest pain. ...Read moreSee 1 more doctor answer
I have been told I may have MS 12 years ago I take Copaxone (glatiramer) sq daily - hip flexor rt leg how can I improve my walking ?
That's odd...: It is extremely unusual to be diagnosed with MS at age 66. Especially the relapsing-remitting type, which Copaxone (glatiramer) treats. I recommend seeing an MS subspecialist to confirm the diagnosis. Second, without examining you it's hard to know why your walking changed, and what to do about it. Thirdly, even if you do have MS, it doesn't protect you from other diseases which could change your walking. ...Read moreSee 1 more doctor answer
I have a possible diagnosis of MS . Have been prescribed copaxone (glatiramer). I still have hip flexor muscle not functioning properly. What can I do to be walk?
MS symptom mgmt: Natural remedies to try: low-intensity aerobic exercise 3-6 days a week; stretching exercises daily; good sleep hygeine, 7-8 hours nightly; tonic water, 1-2 l/day; deep, hard muscle massage of your legs every 2 hours or as often as you can tolerate. Meds may help, such as muscle relaxants, dalfampridine, compound topical pain gels, and possibly others. Ask your neurologist, & good luck! ...Read moreSee 3 more doctor answers
Is the eastern practice of oil pulling safe for MS patients? Looking for natural compliments to my copaxone (glatiramer) and vitamin D3 treatment.
Would caution you: Amazing how many ms patients feel desperate and begin searching for solutions which are promoted online and in alternative journals, most of which are clearly deceptive and bogus. Forget "oil pulling" and gimmicks. If you are not doing well, make sure your vitamin d level is about 50-60ng/ml, avoid smoking, use low fat, low salt diet. Maybe switch to Gilenya or tysabri (natalizumab). ...Read more
Was on many medications for confirmed MS (rebif, copaxone, gilenya, tysabri, (natalizumab) tecfidera) none helped control.. Is this typical of ms? Next step?
Unusual but possible: Visit an ms center.Get a more detailed answer ›
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