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Doctor insights on: Glatiramer Allergy In Children

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Dr. John Chiu
2,638 doctors shared insights

Allergies (Definition)

Allergies occur when your immune system is triggered by envirionmental factors it should ignore--for example, pollen in the air, or dander on a cat or dog--and creates cells to fight against them. An allergic reaction typically causes itching, congestion, or drainage, and ...Read more


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Glatiramer acetate (copaxone) vs. Interferon?

Glatiramer acetate (copaxone) vs. Interferon?

See answer below: Both are used in rrms with similar efficacy levels. Copaxone (glatiramer) does not need blood monitoring and is administered as a subcutaneous sc injection daily. Side effects include injection site reactions. Interferons need lab work monitoring, can be a weekly injection into a muscle (avonex), every other day sc (betaseron) or three times a week sc (rebif). Most commo side effects include flu-like symptoms. ...Read more

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Does copaxone (glatiramer) increase cancer risk?

Does copaxone (glatiramer) increase cancer risk?

NO !: To my knowledge glatimair acetate (cop axone) has not been found to be carcinogenic. ...Read more

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What does copaxone (glatiramer) do for multiple sclerosis?

What does copaxone (glatiramer) do for multiple sclerosis?

Some control: Decrease relapses about 29%, forestalls disability, and may prevent MRI lesions. Works by controlling inflammatory lymphocyte attack on brain and spinal cord. Is a modestly potent medication, and works more effectively in the newer 40 mg TIW formulation. ...Read more

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What does copaxone (glatiramer) do for multiple sclerosis?

What does copaxone (glatiramer) do for multiple sclerosis?

Some control: Decrease relapses about 29%, forestalls disability, and may prevent MRI lesions. Works by controlling inflammatory lymphocyte attack on brain and spinal cord. Is a modestly potent medication, and works more effectively in the newer 40 mg TIW formulation. ...Read more

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How effective is copaxone (glatiramer) for the treatment of ms?

How effective is copaxone (glatiramer) for the treatment of ms?

Somewhat: Copaxone is seemingly the most used drug for ms, but likely intermediate in efficacy. We use relapse rate reduction c/w placebo, as one measure, and Copaxone has been shown consistently to have a 29% rrr. This is about the range for betaseron, and rebif. Contrast to tysabri, (natalizumab) about 68%, Gilenya 54%, and a promising drug bg-12, 44-53%. The choice of a med should also consider risk. ...Read more

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How fast should it take for copaxone (glatiramer) to work to stop multiple sclerosis flareups?

How fast should it take for copaxone (glatiramer) to work to stop multiple sclerosis flareups?

Variable: Copaxone (glatiramer) is a first line agent which may not be useful for many pts, and may take up to 4-6 months to reach maximal potency in some pts. If relapses continue to occur, and your MRI shows active lesions, other meds may be better choices for you. Discuss thoroughly with your neurologist. ...Read more

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What are the side effects for taking oral MS drugs as opposed to copaxone (glatiramer) and all the other injectable drugs.

What are the side effects for taking oral MS drugs as opposed to copaxone (glatiramer) and all the other injectable drugs.

Complex : All ms drugs have potential side effects, and Copaxone has injection site reactions, lipoatrophy, an occasional chest/flushing reaction, and of course, the need to inject. All three orals are well tolerated in most folks, but tecfidera may cause severe nausea, diarrhea. Better tolerated might be Gilenya (fingolimod) or aubagio. Talk to neurologist about your best approach. ...Read more

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What do you suggest if my child has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) what do we do?

What do you suggest if my child has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) what do we do?

Call company: Often the pharmaceutical companies will have assistance programs for patients that can't afford their medications. I would try contacting them. Of course , she could also get insurance via Affordable Care Act. ...Read more

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What's the most effective medication for secondary progressive multiple sclerosis? My dr has me on copaxone (glatiramer) for almost a year now and it's not helping

Multiple sclerosis: With the exception of Novantrone (mitoxantrone) and steroids there is no other approved therapy for secondary progressive ms. The new oral therapies and old injectable platform therapies are only effective in relapsing ms (slow down number of relapses over time) not effective in progressive ms. Physical therapy, ampyra, (dalfampridine) muscle relaxer and other medications could be used to improve symptoms of ms. ...Read more

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How close in relationship is tecfidera & copaxone (glatiramer)?

How close in relationship is tecfidera & copaxone (glatiramer)?

VERY DIFFERENT: Entirely different chemical classes, with distinct different mechanisms of action, and outcome data. Both seem safe, Copaxone (glatiramer) tho is injected daily, causes lipoatrophy, hypertension, and injection reactions. Tecfidera may be tough to tolerate due to flushing, nausea, diarrhea, stomach pain. Copaxone (glatiramer) relapse reduction is 29%, but tecfidera, drops 44-52%, oral twice daily, no needles. Talk to doc. ...Read more

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In lady patients with ms, should they stop taking copaxone (glatiramer) when trying to get pregnant?

In lady patients with ms, should they stop taking copaxone (glatiramer) when trying to get pregnant?

PERTAINENT QUESTION: Likely, Copaxone (glatiramer) safe, as fda considers it a category b drug, but, usually, i suggest holding it for a while before conception, just to be extra cautious. Also, pregancy is clearly protective, and being off the Copaxone (glatiramer) is not risky then. After labor and delivery, i restart within 48 hrs, as we need to prevent post-partum relapses, which can occur about 6-8 weeks after baby arrives. ...Read more

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I have started my medication in june (which is an injection of copaxone (glatiramer) everyday) I have yet to get my period?

I have started my medication in june (which is an injection of copaxone (glatiramer) everyday) I have yet to get my period?

Unusual reaction: Copaxone (glatiramer) does NOT usually affect hormonal function, and need to have your gynecologist assess this. Sounds like a co-morbidity rather than a direct relationship, but unique reactions can and do occur. If no explanation otherwise, perhaps not a bad idea to try a different disease modifying agent. ...Read more

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My daughter has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) Any OTC medications she can take instead?

My daughter has lost her job and we will not be able to afford her next shipment of copaxone, (glatiramer) Any OTC medications she can take instead?

Contact prescriber: Copaxone (glatiramer) is a specific combination of biologic agents used for treating MS (L-alanine, L-Lysine, L-glutamic acid and L-Tyrosine) . Try discussing with her prescribing doctor - there may be a way to get a short supply of her meds at a discounted price for a while. ...Read more

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How long do side effects of copaxone (glatiramer) last?

How long do side effects of copaxone (glatiramer) last?

Variable.: Local injection site pain may last a few minutes, unless the area becomes infected or swollen. Dimpling in the injection site, lipoatrophy, occurs in up to 60% of patients, and may be permanent. Brief injection rxtns associated with chest pain, flushing, sweating, etc, are rare and benign and last about 15 min. Hypertension may occur, and, if so, may be permanent. ...Read more

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How long do bad side effects to copaxone (glatiramer) last?

How long do bad side effects to copaxone (glatiramer) last?

See answer below: Most common side effects of Copaxone (glatiramer) are injection site reactions with redness or welts that can last a few days. Occasionally, patients will report severe chest pain that occurs once or twice a month and is limited to 3-5 minutes in duration. More rarely, patients will report flushing in the face followed by severe chills and incontinence that can last up to 3 hours. ...Read more

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How long does it take for copaxone (glatiramer) to reach full potential for ms?

How long does it take for copaxone (glatiramer) to reach full potential for ms?

Variable.: Local injection site pain may last a few minutes, unless the area becomes infected or swollen. Dimpling in the injection site, lipoatrophy, occurs in up to 60% of patients, and may be permanent. Brief injection rxtns associated with chest pain, flushing, sweating, etc, are rare and benign and last about 15 min. Hypertension may occur, and, if so, may be permanent. ...Read more

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How likely is nmo to be fatal now days? Will medicines like copaxone (glatiramer) help?

How likely is nmo to be fatal now days? Will medicines like copaxone (glatiramer) help?

NMO: In the old days, we thought that nmo was a variant of ms. Now we realize that it is very different, although may present the same way. Because it is so rare, there will never be enough people in an fda trial to approve a drug therapy. I have had success with rituxan (rituximab). Two men in this country are the leading experts on the topic, dean wingerchuck at mayo clinic and ben greenberg at utsw. ...Read more

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Is it safe to take copaxone (glatiramer) or rebif as a treatment for ms?

Is it safe to take copaxone (glatiramer) or rebif as a treatment for ms?

Yes, but see below: Both, especially Copaxone (glatiramer) are quite safe, but require injections, with risk of skin reactions with both, and permanent site dimpling with copaxone (glatiramer). Rebif can cause flu-like rxtns, depression, liver issues, thyroid problems, in addition. Copaxone (glatiramer) may have brief chest pain, breathlessness, and flushing after injection.(hypertension is reported) Copaxone (glatiramer) is safer for pregnancy. ...Read more

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What are the side effects of glatiramer for multiple sclerosis patients?

Infrequent, but: Injection site reactions can be seen, usually just reddening, but may see more intense local reaction. A less frequent injection reaction involves throat and chest pain, flushing sensation over face and chest, tingling, and generalized malaise lasting several minutes. This is not a heart issue, and turns out to be quite benign but can be very scary. ...Read more

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Is copaxone (glatiramer) safe for women who are pregnant or breastfeeding?

Is copaxone (glatiramer) safe for women who are pregnant or breastfeeding?

Depends: This medication suppresses your immune system. We don't have any good information on it in pregnancy. It really is a case of discussing with your doctor the risks and benefits. In breastfeeding, we don't have a lot of information but it is a pretty big molecule and probably doesn't end up in breast milk so we feel comfortable with women breastfeeding on this med. ...Read more

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Have ms. On Copaxone (glatiramer) but missed a few doses. Worried about my brainstem lesions and if they mean a worsened prognosis or risk of death?

Have ms. On Copaxone (glatiramer) but missed a few doses. Worried about my brainstem lesions and if they mean a worsened prognosis or risk of death?

No immediate risk!: Consult your specialist to make sure that your Copaxone (glatiramer) has prevented MS relapse Usually an MRI with and without Gadalinium injection would tell us if the condition is active Although you should take your Copaxone (glatiramer) regularly missing couple of injections is not a big problem but don't miss anymore!! There is NO risk of death ...Read more

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I have had tingling/numbness in my finger tips since july 13 and i take copaxone (glatiramer). I wanted to know is there a medication to stop numbness?

I have had tingling/numbness in my finger tips since july 13 and i take copaxone (glatiramer). I wanted to know is there a medication to stop numbness?

Need a diagnosis: If the numbness is due to ms, you may be experiencing a relapse, and that could be treated with a steroid or acth. If the numbness is due to a peripheral nerve issue such as carpal tunnel, this could be treated directly. You need to discuss with your doctor and search out the etiology and then address with specific intervention. You see, ms can co-exist with other problems and these need eval. ...Read more

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Why would my neurologist since 2011, have me on copaxone (glatiramer) injections, telling me I have ms, put in her notes, she does not believe I have ms?

Why would my neurologist since 2011, have me on copaxone (glatiramer) injections, telling me I have ms, put in her notes, she does not believe I have ms?

My response: We are not able to mediate doctor- patient communications, and I personally do not have capacity to read minds. Since you are taking an expensive injectable medication, would directly address this with your doctor, and if necessary, get a second opinion. ...Read more

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Ms - started rebif after a severe allergic reaction to copaxone (glatiramer). Now extremely itchy. Could it be the rebif or the MS itch?

Ms - started rebif after a severe allergic reaction to copaxone (glatiramer). Now extremely itchy. Could it be the rebif or the MS itch?

Could be side fx: Rebif and copaxone (glatiramer) are not the same, but your symptom of itching could be caused by your new medicine. If it does not subside soon, say 2-3 days, it may be helpful to make a change, or use some kind of treatment for the possible side effects. ...Read more

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If I have a weak immune system due to copaxone, (glatiramer) does that make me more susceptible to cancer?

If I have a weak immune system due to copaxone, (glatiramer) does that make me more susceptible to cancer?

Probably not: The largest studies of long-term Copaxone (glatiramer) use do not show a significantly increased risk of cancers. However, there is a theoretical risk that decreasing the activity of the immune system could increase the chances of a cancer developing or growing more quickly. These concerns should be discussed with your neurologist so you can weigh this small risk against the benefits of this ms treatment. ...Read more

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Taking copaxone (glatiramer) for many years for my MS . I have pain in my right big toe with inflamation . Could my body systems not want me to take it .... Gout?

Taking copaxone (glatiramer) for many years for my MS . I have pain in my right big toe with inflamation .  Could my body systems not want me to take it .... Gout?

Need to reassess: At your current age, 77, you may no longer need copaxone, (glatiramer) and if you developed a secondary progressive ms transition, this drug would not be appropriate to handle that either. The pain in your toe could be gout, but other explanations may be considered. Yes, check your uric acid, but also update MRI of brain, and get full neurological re-evaluation. ...Read more

Glatiramer (Definition)

Glatiramer is a nasal preparation which is a kind of ...Read more


Dr. Colin Sanner
31 doctors shared insights

Copaxone (Definition)

Copaxone is a nasal preparation which is a kind of ...Read more