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Doctor insights on: Gilenya Multiple Sclerosis

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Multiple sclerosis = demyelination?

Multiple sclerosis = demyelination?

Characteristic: Demyelination refers to damage to the coverings of the nerves in the brain and spinal cord, and is very characteristic of the inflammatory process that occurs in ms. This can also occur in children with hereditary leukodystrophies, and can be associated with acquired neurological disorders. The disease modifying drugs in MS are designed to control demyelination and many work well. ...Read more

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Dr. Mark Ingerman
3 doctors shared insights

Sclerosis (Definition)

We neurologists employ the term to describe localized damage involving the central nervous system, and sclerosis means scarring. If in many areas, might be multiple sclerosis. If affecting the motor nerve cell, ...Read more


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Best multiple sclerosis medications?

Best multiple sclerosis medications?

Interferons ? : There is no best medication , some would suit the patient better than others but interferons are the most widely used for prevention of attacks. ...Read more

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Is multiple sclerosis preventable?

Is multiple sclerosis preventable?

No: Population studies have suggest that mononucleosis in adolescence, smoking, and possibly childhood obesity are risks for developing ms. However ms is a complex variable disease requiring genetic predisposition along with some environmental trigger(s), possibly influenced by hormones, immune system priming from certain infectious agents. ...Read more

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Is multiple sclerosis hereditary?

Is multiple sclerosis hereditary?

Complex: Multiple sclerosis is an issue of genetic susceptibility, not the usual heredity, and risk runs about 3-5% if mother has it, 1-2% if father has it. But without specific environmental triggers, the disease will be unlikely to manifest. ...Read more

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Is multiple sclerosis fatal?

Is multiple sclerosis fatal?

Not usually: Ms is a chronic neurological condition, characterized by episodes of neurological disability of variable severity and recovery. A minority of inidividuals can have a very aggressive course, and become so disabled that they are at risk of secondary medical complications which may be fatal. There are subtypes of MS which are so aggressive that a fatal outcome can happen. Fortunately these are rare. ...Read more

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What symptoms of ms multiple sclerosis ?

What symptoms of ms multiple sclerosis ?

Variable: Please consult this site for information on early symptoms of MS http://www.webmd.com/multiple-sclerosis/guide/multiple-sclerosis-symptoms Wish you good health. ...Read more

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Who discovered multiple sclerosis?

Who discovered multiple sclerosis?

Charcot: The French neurologist Charcot is credited with identifying MS as a distinct entity for the first time. ...Read more

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Is amyotrophic lateral sclerosis a type of multiple sclerosis (ms)?

Not similar diseases: Als is very different, and is a disease of "mis-folded proteins" like alzheimers and parkinson's, and all of these affect older people. Ms is an autoimmune disease afflicting younger patients who have hereditary susceptibilities and environmental exposures. Ms can be successfully treated and controlled, but ALS does not respond well to current therapies. ...Read more

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Iis there anyone who has multiple sclerosis and taking tysabri (natalizumab)?

Tysabri (natalizumab): I dont know the numbers but there are several patients who are taking injections of tysabri (natalizumab). ...Read more

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What disease might mimic multiple sclerosis?

What disease might mimic multiple sclerosis?

Several potentials: Cadasil, lupus, arteritis, clippers, pernicious anemia, cervical spondylosis, lyme disease, CNS lymphoma, sjogren's, melas. If you get the point, ms may be hard to diagnose, and often need to exclude other explanations. Patterns may or may not be different, and sometimes it is important to get testing and even several opinions. ...Read more

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Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Optic neuritis (nmo) or multiple sclerosis (ms)? What are the different victims?

Say what???: This question is confusing! optic neuritis (abbreviated on) is one of many symptoms of ms and results from inflammation in one or both optic nerves. It is one of the most common symptoms of ms and typically causes eye pain and decreased vision in one eye. It does not typically cause complete blindness. Multiple sclerosis (ms) is an autoimmune disorder of the center nervous system. See below. ...Read more

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Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Are multiple sclerosis and myasthenia gravis conditions of the neuroglia?

Neither of them: Neither of these conditions is a condition of the neuroglia. To some extent, glial cells are involved in the repair of damage that occurs in MS. Myasthenia is a condition that occurs at the junction of the nerve and muscle, no glia cells are present there. ...Read more

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Is primary progessive multiple sclerosis always fatal?

Is primary progessive multiple sclerosis always fatal?

Not necessarily : Ms has been said to shorten life span, and untreated this is correct, but several studies have supported normal life if appropriate potent meds are employed. Primary progressive ms does not respond well to the usual meds, and mostly symptomatic interventions are used. There are many research projects nowadays, and best to contact a medical school and get involved. ...Read more

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Is multiple sclerosis progressive and fatal?

Prog.disease: There is a variant form of MS that is very aggressive that can lead to coma or death. However most of the other forms do not have such a grave prognosis. If left untreated >30 % of patients will develop significant disability within 20->25 years after onset. Life expectancy is shortened only slightly, death usually results from secondary complications. ...Read more

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What does copaxone (glatiramer) do for multiple sclerosis?

What does copaxone (glatiramer) do for multiple sclerosis?

Some control: Decrease relapses about 29%, forestalls disability, and may prevent MRI lesions. Works by controlling inflammatory lymphocyte attack on brain and spinal cord. Is a modestly potent medication, and works more effectively in the newer 40 mg TIW formulation. ...Read more

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Can multiple sclerosis be mis-diagnosed?

Not uncommonly: There are several disease states that can mimic multiple sclerosis, and MRI lesions can likewise be misleading. Since this is so very complex, it is best to seek additional opinions from physicians who specialize in the area, as the diagnosis may not always be easy to reach. ...Read more

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What are neuropsychiatric problems associated with multiple sclerosis ?

What are neuropsychiatric problems associated with multiple sclerosis ?

Significant at times: Main issue is evolution of progressive cognitive loss, which likely is present in at least 60% and creates an early disability. Lack of emotional control, such as crying or laughing without reason, or more persistent euphoria or depression gets even more challenging. Although delusions and hallucinations may be rarely seen, usually not an issue. ...Read more

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What are demyelination diseases other than ms?

What are demyelination diseases other than ms?

See answer below: There are several demyelinating disease in the central nervous system. Among those, adem (acute disseminated encephalomyelitis), nmo (neuro myelitis optica), marburg or fulminant inflammatory demyelinating disease (idd) etc... Seek the help of a neurologist in order to be properly diagnosed and properly treated as treatments vary for these different conditions. ...Read more

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What are the benefits of tysabri (natalizumab) v. Other MS drugs?

What are the benefits of tysabri (natalizumab) v. Other MS drugs?

Hard to answer: Tysabri (natalizumab) is a potentially effective treatment for MS but your question would be difficult to answer. Tysabri (natalizumab) is approved for the treatment of aggresive or refractory MS where other equally effective medications have not worked. This is because of a possibly fatal side effect called pml which may cause more damage than the disease. Use requires an experienced doctor and close monitoring. ...Read more

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Dr. Bennett Machanic
1,453 doctors shared insights

Multiple Sclerosis (Definition)

A progressive disease that interferes with the functioning of the central nervous system and brain. Symptoms include numbness, impairment of speech and muscular coordination, blurred ...Read more