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Doctor insights on: Giant Cell Tumor In Children

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What is extracranial germ cell tumor of childhood?

What is extracranial germ cell tumor of childhood?

Rare family: This is a family of tumors that can be diagnosed by a pathologist (i suggest you get a consensus from 3 of us) that resemble to some degree the gametes and/or the cells of the unborn child. They run from totally benign to very malignant; thankfully today's treatment produces many good responses. ...Read more

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Neoplasms (Definition)

"tumor" literally translates as "mass", so even a fresh bruise could be called a "tumor". Doctors use the term "neoplasm" (tranlates literally as new growth) to describe tumors that are abnormal growths of cells. These may be benign or malignant; "malignant" = cancer. In everyday usage, we use "tumor" ...Read more


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What is the incidence for extragonadal germ cell tumors?

Very low: Compared to the gonadal germ cell tumors. The most common locations are the mediastinum, the pineal gland in the brain and the abdomen. ...Read more

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With germ cell tumor that to deal with germ cell tumor cancer?

With germ cell tumor that to deal with germ cell tumor cancer?

Clarify, can be CA.: These can be cancer. These are tumors of germ cells which can be from the gonads, or ovary and testis, or from outside these areas and occur during embryonic development. These can be cancerous or non-cancerous. Prognosis varies. Some, like seminoma, have a very good prognosis. ...Read more

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Are mast cell tumors people tumors or dog tumors?

Are mast cell tumors people tumors or dog tumors?

I know humans: I don't know about dogs, but humans can get systemic mastocytosis. An uncommon clonal growth of mast cells. Mast cells may also be reactive, such as from allergies. ...Read more

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What causes Glioblastoma in brainstem, & high grade glioma in brainstem in young adults?Thought brainstem had no glial cells to cause this in adults?

What causes Glioblastoma in brainstem, & high grade glioma in brainstem in young adults?Thought brainstem had no glial cells to cause this in adults?

It's just bad luck: There are a few genetic syndromes that increase risk for glioblastoma / "high grade glioma", but beyond this it's simply a misfortune. All cancers arise from random mutations -- these are totally dumb luck. Anybody who told you that the brainstem has no glial cells is somebody you either misunderstood or simply shouldn't listen to. It's got a lot more glia than neurons like the rest of the brain. ...Read more

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Is anaplastic medulloblastoma a brain or childhood cancer?

Is anaplastic medulloblastoma a  brain or childhood cancer?

Anaplastic medullo: Medulloblastoma is the most common malignant brain tumor (or cancer) in children. Anaplastic medulloblastoma is a particular subtype of this disease. While almost all cases of medulloblastoma occur in children, this disease can also rarely occur in adults. ...Read more

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Are wilm's tumor associated with brain tumors later in life?

Are wilm's tumor associated with brain tumors later in life?

Occasionally: Secondary cancer. Wilms tumor survivors have a small risk of developing another type of cancer within 15 years after wilms tumor was first diagnosed. The most important risk factors are whether treatment included radiation therapy and doxorubicin. Wilms tumor in children can also spread or metastasis thru the bloodstream to the brain, lungs or lymph nodes occasionally in children. ...Read more

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Why is pituitary adenoma infratentorial in adult tumors but craniopharyngioma is supratentorial in childhood?

Why is pituitary adenoma infratentorial in adult tumors but craniopharyngioma is supratentorial in childhood?

Sella Turcica: The tentorium cerebelli separates the cerebellum from the cerebrum. Supratentorial means ABOVE the tentorium and Infratentorial means BELOW. The pituitary gland sits in a special area called the hypophyseal fossa or sella turcia which is technically neither. Craniopharyngioma and pituitary adenoma grow SUPRATENTORIALLY in almost all cases, but rarely invade the clivus into the posterior fossa. ...Read more

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Can squamous cell cancer begin in the brain?

Can squamous cell cancer begin in the brain?

Yes: It is rare, and when it is truly primary rather than having spread from the ear or metastasized from the lung, it has begun in a dermoid cyst in a person with partial absence of the corpus callosum. ...Read more

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Has giant cell or temporal arteritis ever found to be hereditary?

Has giant cell or temporal arteritis ever found to be hereditary?

TA hereditary?: Recent research has indicated that genetic (inherited) factors play a role in who becomes afflicted with the illness. Theories have included viral stimulation of the immune system in genetically susceptible individuals. ...Read more

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Can adults develop extracranial germ cell tumors too?

Can adults develop extracranial germ cell tumors too?

Yes.: Adults can develop extracranial germ cell tumors. These can be either benign or malignant. Behavior of these tumors depends upon the location / the organ (site) in which the tumor develops and upon the microscopic and molecular-genetic features of the individual tumor. Hope that this helps. ...Read more

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Could sickle cell occur in african/english children?

Could sickle cell occur in african/english children?

Yes: The sickle cell mutation occurs in a variety of populations around the world. It is more common in sub saharan africa but exists in a variety of ethnic groups. ...Read more

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Could teenagers have renal cell carcinoma?

Could teenagers have renal cell carcinoma?

Yes: It's not common. If it does appear, it raises suspicion for a hereditary predisposition (von hippel - lindau, others). There are a few pediatric kidney cancers that mimic common renal cell carcinoma clinically but are distinct pathologic entities. ...Read more

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Testicular cancer: what is a non seminomous germ cell tumor?

Testicular cancer: what is a non seminomous germ cell tumor?

Potentially serious: A nonseminomatous germ cell tumor is a malignancy that has multiple origins within the testicle. It is less common, but potentially more serious, than seminomas of the testicle. Early and aggressive treatment is necessay and can lead to cure in many patients that present with limited disease. Systemic chemotherapy is now available for patients that present with advanced tumors. ...Read more

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What is "rare epithelioid giant cells" in fna of thyroid nodules?

What is "rare epithelioid giant cells" in fna of thyroid nodules?

Review with your MD: Usually, when one aspirates a thyroid cyst one may see "rare epithelioid giant cells". Most simple cysts of the thyroid are benign. However, fine needle aspirate of cystic papillary thyroid carcinoma may also show this feature and may lack diagnostic cells. So, additional information is needed to interpret the cytology report. ...Read more